Investigating the nature of the Fried Egg nebula: CO mm-line and optical spectroscopy of IRAS 17163-3907

Through CO mm-line and optical spectroscopy, we investigate the properties of the Fried Egg nebula IRAS 17163-3907, which has recently been proposed to be one of the rare members of the yellow hypergiant class. The CO J=2-1 and J=3-2 emission arises from a region within 20" of the star and is clearly associated with the circumstellar material. The CO lines show a multi-component asymmetrical profile, and an unexpected velocity gradient is resolved in the east-west direction, suggesting a bipolar outflow. This is in contrast with the apparent symmetry of the dust envelope as observed in the infrared. The optical spectrum of IRAS 17163-3907 between 5100 and 9000 {\AA} was compared with that of the archetypal yellow hypergiant IRC+10420 and was found to be very similar. These results build on previous evidence that IRAS 17163-3907 is a yellow hypergiant.Comment: 14 pages including appendix, accepted for publication in A&

Millimeter polarisation of the protoplanetary nebula OH 231.8+4.2: A follow-up study with CARMA

In order to investigate the characteristics and influence of the magnetic field in evolved stars, we performed a follow-up investigation of our previous submillimeter analysis of the proto-planetary nebula (PPN) OH 231.8+4.2 (Sabin et al. 2014), this time at 1.3mm with the CARMA facility in polarisation mode for the purpose of a multi-scale analysis. OH 231.8+4.2 was observed at ~2.5" resolution and we detected polarised emission above the 3-sigma threshold (with a mean polarisation fraction of 3.5 %). The polarisation map indicates an overall organised magnetic field within the nebula. The main finding in this paper is the presence of a structure mostly compatible with an ordered toroidal component that is aligned with the PPN's dark lane. We also present some alternative magnetic field configuration to explain the structure observed. These data complete our previous SMA submillimeter data for a better investigation and understanding of the magnetic field structure in OH 231.8+4.2.Comment: 7 pages, 5 figures, 2 tables. Accepted for publication in MNRA

Estimate of halo ellipticity as a function of radius with flexions

The cold dark matter theory predicts triaxial dark matter haloes. The radial distribution of halo ellipticity depends on baryonic processes and the nature of dark matter particles (collisionless or collisional). Here we show that we can use lensing flexion ratios to measure the halo ellipticity as a function of radius. We introduce a weight function and study the relationship between the first and second order statistics of flexion ratios, both of which can be used to reduce the bias in the estimate of ellipticity. we perform numerical tests for our method, and demonstrate that it can reduce the bias and determine the halo ellipticity as a function of radius. We also point out that the minimum mean flexion ratio can be used to trace the centres of galaxy clusters.Comment: 9 pages,9 figures, MNRAS accepte

A Trial of a 7-Valent Pneumococcal Conjugate Vaccine in HIV-Infected Adults.

BACKGROUND: Streptococcus pneumoniae is a leading and serious coinfection in adults with human immunodeficiency virus (HIV) infection, particularly in Africa. Prevention of this disease by vaccination with the current 23-valent polysaccharide vaccine is suboptimal. Protein conjugate vaccines offer a further option for protection, but data on their clinical efficacy in adults are needed. METHODS: In this double-blind, randomized, placebo-controlled clinical efficacy trial, we studied the efficacy of a 7-valent conjugate pneumococcal vaccine in predominantly HIV-infected Malawian adolescents and adults who had recovered from documented invasive pneumococcal disease. Two doses of vaccine were given 4 weeks apart. The primary end point was a further episode of pneumococcal infection caused by vaccine serotypes or serotype 6A. RESULTS: From February 2003 through October 2007, we followed 496 patients (of whom 44% were male and 88% were HIV-seropositive) for 798 person-years of observation. There were 67 episodes of pneumococcal disease in 52 patients, all in the HIV-infected subgroup. In 24 patients, there were 19 episodes that were caused by vaccine serotypes and 5 episodes that were caused by the 6A serotype. Of these episodes, 5 occurred in the vaccine group and 19 in the placebo group, for a vaccine efficacy of 74% (95% confidence interval [CI], 30 to 90). There were 73 deaths from any cause in the vaccine group and 63 in the placebo group (hazard ratio in the vaccine group, 1.18; 95% CI, 0.84 to 1.66). The number of serious adverse events within 14 days after vaccination was significantly lower in the vaccine group than in the placebo group (3 vs. 17, P=0.002), and the number of minor adverse events was significantly higher in the vaccine group (41 vs. 13, P=0.003). CONCLUSIONS: The 7-valent pneumococcal conjugate vaccine protected HIV-infected adults from recurrent pneumococcal infection caused by vaccine serotypes or serotype 6A. (Current Controlled Trials number, ISRCTN54494731.) Copyright 2010 Massachusetts Medical Society

Dairy farming and dairy industry in Iran

Iran is a country with a long dairy tradition. Dairy production has increased to a level of about 9bn kg of milk per year. The ambition in the sector is to further increase production and to improve the quality of the milk to be able to export. Based on the analysis of available data and on a field trip to Iran, 4 key areas have been identified by the participating partners in the project where a Dutch Iranian cooperation could strengthen the Iranian dairy chain. 1. Milk quality assurance, quality standards and milk-payment systems There is a lack of trust within the Iranian dairy chain. A further improvement of the milk quality is needed if Iran wants to export. Dutch experience and technology about how to organise (governance) and implement (e.g in milk-payment systems) with all relevant stakeholders to achieve a higher quality of consumer products can help solve this issue. 2. Feed availability and quality The lack of trust also applies to the feed part of the dairy chain. Chain efficiency can be improved considerably if trust is improved. Dutch experience and technology about how to organise and implement independent assessment of feed quality and building trust in the chain can help to make the Iranian chain more transparent and efficient. 3. Water efficiency and feed production Iran has to be more efficient in its feed production, especially in relation to water use. Dutch international experience in crop production and water efficiency on farm level and knowledge on policy development on regional and national level can be used to contribute to this issue. 4. Education: both on operational level and on economics All Iranian farmers mentioned the need for operational trainings of their employees. Several had done training in the Netherlands in the past. The changing circumstances in Iran require more skills and insights related to strategic and economic decisions. The main recommendation is to develop a joint programme with Iranian and Dutch partners to work on these four areas. Possible partners for such a programme have been identified on both sides

Burden of visceral leishmaniasis in villages of eastern gedaref state, Sudan: an exhaustive cross-sectional survey.

Since December 2009, Médecins Sans Frontières has diagnosed and treated patients with visceral leishmaniasis (VL) in Tabarak Allah Hospital, eastern Gedaref State, one of the main endemic foci of VL in Sudan. A survey was conducted to estimate the VL incidence in villages around Tabarak Allah

Radio Observations of New Galactic Bulge Planetary Nebulae

We observed 64 newly identified galactic bulge planetary nebulae in the radio continuum at 3 and 6 cm with the Australia Telescope Compact Array. We present their radio images, positions, flux densities, and angular sizes. The survey appears to have detected a larger ratio of more extended planetary nebulae with low surface brightness than in previous surveys. We calculated their distances according to Van de Steene & Zijlstra (1995). We find that most of the new sample is located on the near side around the galactic center and closer in than the previously known bulge PNe. Based on H-alpha images and spectroscopic data, we calculated the total H-alpha flux. We compare this flux value with the radio flux density and derive the extinction. We confirm that the distribution of the extinction values around the galactic center rises toward the center, as expected.Comment: accepted for publication in A&

Is Work-Related Rumination Associated with Deficits in Executive Functioning?

Work-related rumination, that is, perseverative thinking about work during leisure time, has been associated with a range of negative health and wellbeing issues. The present paper examined the association between work-related rumination and cognitive processes centred around the theoretical construct of executive functioning. Executive functioning is an umbrella term for high level cognitive processes such as planning, working memory, inhibition, mental flexibility; and it underlies how people manage and regulate their goal directed behaviour. Three studies are reported. Study I, reports the results of a cross-sectional study of 240 employees, and demonstrates significant correlations between work-related rumination and three proxy measures of executive functioning: cognitive failures (.33), cognitive flexibility (-.24) and situational awareness at work (-.28). Study II (n = 939), expands on the findings from study 1 and demonstrates that workers reporting medium and high work-related rumination were 2.8 and 5 times, respectively, more likely to report cognitive failures relative to low ruminators. High ruminators also demonstrated greater difficulties with ‘lapses of attention’ (OR = 4.8), ‘lack of focus of attention’ (OR = 3.4), and ‘absent mindedness’ (OR = 4.3). The final study, examined the association between work-related rumination and executive functioning using interview data from 2460 full time workers. Workers were divided into tertiles low, medium and high. The findings showed that high work-related rumination was associated with deficits in starting (OR = 2.3) and finishing projects (OR = 2.4), fidgeting (OR = 1.9), memory (OR = 2.2), pursuing tasks in order (OR = 1.8), and feeling compelled to do things (OR = 2.0). It was argued that work-related rumination may not be related to work demands per se, but appears to be an executive functioning/control issue. Such findings are important for the design and delivery of intervention programmes aimed at helping people to switch off and unwind from wor

The application of strength and power related field tests in older adults:criteria, current status and a future perspective

Leg muscle strength (LMS) and leg muscle power (LMP) are determinants of aspects of functional status and important parameters for measuring intervention effects in older adults. Field tests are often used for the evaluation of LMS and LMP in older persons. However, criteria important for the application of strength and power related field tests in older adults have not been systematically taken into account and are not yet fully listed and described in a single publication. Therefore, this paper describes criteria important for the application of strength and power related field tests in older adults. In addition, strength and power related field tests commonly used in older adults are evaluated by using the described criteria. Based on this evaluation, this paper provides a perspective on the further development of field tests. Criteria important for strength and power related field tests are: adequate accuracy, precision, concurrent validity, clinical validity, practical feasibility and pure strength or power outcomes. Commonly used strength and power related field tests do not meet all the aforementioned criteria. Therefore, further development of field tests is necessary. Mobile sensing systems are potentially useful for the evaluation of LMS and LMP in older adults. Mobile sensing systems do not have the limitations of commonly used field tests and provide important additional advantages. In particular, mobile sensing systems offer the opportunity of continuous monitoring during free-movement in the home-environment, thereby reducing the need of standardized assessments by health-care professionals. Future studies should examine the clinical validity of mobile sensing systems and evaluate the application of sensor technology in exercise-based interventions