17 research outputs found

    Self-assessment of academic achievements in the examination situation and personality traits of students of the youth age period

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    The study presents the results of the correlation between students’ predictive competence and their personal characteristics. The relevance and novelty of the research results are attributed to the specification of the problematic issue connected with predictive competence. The latter is determined through the students’ subjective characteristics which are associated with self-assessment of academic achievements in the examination situation. The developed predictive competence is one of the acmeological invariants of professionalism and a resource that increases stress resistance. The aim of the research is to study the correlation between personality traits of students of the youth age period and the adequacy of their self-assessment of the academic achievements in a stressful examination situation. The study hypothesizes that personal characteristics of students determine the adequacy level of their self-assessment of the academic results and reduce the level of examination stress. The sample of the study comprises 287 first- and second-year students of the youth age period, majoring in natural sciences and socio-economic educational areas and specialties of Udmurt State Agrarian University (Izhevsk) (their average age is 18.5; 45% are girls, 55% are boys). The methods (tools) of the research are as follows: in order to fix the components of self-assessment of academic achievements and the level of mental tension of young people in the examination situation, the authors used the Dembo – Rubinstein technique (in the original modification); to determine the features of predictive skills, the “Anticipatory Consistency Test” developed by V. D. Mendelevich (ACT) was used; to measure the manifestations of anxiety as a personal quality that affects the stress level during examinations, the “The Taylor Manifest Anxiety Scale” was applied (adapted by T. A. Nemchin, V. G. Noskaridze), to measure the level of the control locus the “Rotter’s Locus of Control Scale” (adapted by E. F. Bazhin, E. A. Golynkina, A. M. Etkind) was used. The study results. Positive correlation between the locus of control and personal anxiety and negative cor- relation between the predictive competence and situational tension are characteristic of students with an adequate self-assessment of academic achievements. Developed predictive competence reduces the exam stress. The conclusion. Adequate self-assessment of academic achievements in a stressful situation contributes to the management of one’s own activities and to a better manifestation of competencies while performing intellectual tests. The obtained results are used to improve the personality-oriented program for the development of adequate self-assessment of academic achievements which serves as a stress resistance resource of students of the youth age period

    Studying the role of genes to be induced in the cell cycle of mammals in the processes of dna replication

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    The behaviour of slightly non-ideal base-gas in the magnetic field is first studied; it is shown that such a system can be considered as a model of a superconductor of the second kind. And explanation of abnormal temperature dependence of the magnetic field penetration depth in high-temperature metal-oxide superconductors is first givenAvailable from VNTIC / VNTIC - Scientific & Technical Information Centre of RussiaSIGLERURussian Federatio

    ABC transporters in Dictyostelium discoideum development

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    ATP-binding cassette (ABC) transporters can translocate a broad spectrum of molecules across the cell membrane including physiological cargo and toxins. ABC transporters are known for the role they play in resistance towards anticancer agents in chemotherapy of cancer patients. There are 68 ABC transporters annotated in the genome of the social amoeba Dictyostelium discoideum. We have characterized more than half of these ABC transporters through a systematic study of mutations in their genes. We have analyzed morphological and transcriptional phenotypes for these mutants during growth and development and found that most of the mutants exhibited rather subtle phenotypes. A few of the genes may share physiological functions, as reflected in their transcriptional phenotypes. Since most of the abc-transporter mutants showed subtle morphological phenotypes, we utilized these transcriptional phenotypes to identify genes that are important for development by looking for transcripts whose abundance was unperturbed in most of the mutants. We found a set of 668 genes that includes many validated D. discoideum developmental genes. We have also found that abcG6 and abcG18 may have potential roles in intercellular signaling during terminal differentiation of spores and stalks

    Trupmeninio Vasiceko modelio parametrų įvertinių asimptotinės savybės

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    We consider the fractional Vasicek model of the form dXt = (α-βXt)dt + γdBHt, driven by fractional Brownian motion BH with Hurst parameter H ∈ (0,1). We construct three estimators for an unknown parameter θ=(α,β) and prove their strong consistency.Nagrinėjamas Vasiceko modelis, valdomas trupmeninio Brauno judesio BH su Hursto indeksuH ∈ (0,1), turintis pavidalą dXt = (α−βXt)dt +γdBHt. Nežinomam parametrui θ = (α,β) sudaromi trys įvertiniaiir įrodomas jų stiprus suderinamumas

    Social amoebae trap and kill bacteria by casting DNA nets

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    Extracellular traps (ETs) from neutrophils are reticulated nets of DNA decorated with anti-microbial granules, and are capable of trapping and killing extracellular pathogens. Various phagocytes of mammals and invertebrates produce ETs, however, the evolutionary history of this DNA-based host defence strategy is unclear. Here we report that Sentinel (S) cells of the multicellular slug stage of the social amoeba Dictyostelium discoideum produce ETs upon stimulation with bacteria or lipopolysaccharide in a reactive oxygen species-dependent manner. The production of ETs by S cells requires a Toll/Interleukin-1 receptor domain-containing protein TirA and reactive oxygen species-generating NADPH oxidases. Disruption of these genes results in decreased clearance of bacterial infections. Our results demonstrate that D. discoideum is a powerful model organism to study the evolution and conservation of mechanisms of cell-intrinsic immunity, and suggest that the origin of DNA-based ETs as an innate immune defence predates the emergence of metazoans

    ACCEPTED Microarray phenotyping in Dictyostelium reveals a regulon of chemotaxis genes. Bioinformatics

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    *To whom correspondence should be addressed Running title: microarray phenotyping reveals chemotaxis regulon 1 Motivation: Coordinate regulation of gene expression can provide information on gene function. To begin a large-scale analysis of Dictyostelium gene function, we clustered genes based on their expression in wild-type and mutant strains and analyzed their functions. Results: We found 17 modes of wild-type gene expression and refined them into 57 sub-modes considering mutant data. Annotation analyses revealed correlations between co-expression and function and an unexpected correlation between expression and function of genes involved in various aspects of chemotaxis. Co-regulation of chemotaxis genes was also found in published data from neutrophils. To test the predictive power of the analysis, we examined the phenotypes of mutations in 7 co-regulated genes that had no published role in chemotaxis. Six mutants exhibited chemotaxis defects, supporting the idea that function can be inferred from co-expression. The clustering and annotation analyses provide a public resource for Dictyostelium functional genomics

    Metagenomic Analysis of Virioplankton from the Pelagic Zone of Lake Baikal

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    This study describes two viral communities from the world’s oldest lake, Lake Baikal. For the analysis, we chose under-ice and late spring periods of the year as the most productive for Lake Baikal. These periods show the maximum seasonal biomass of phytoplankton and bacterioplankton, which are targets for viruses, including bacteriophages. At that time, the main group of viruses were tailed bacteriophages of the order Caudovirales that belong to the families Myoviridae, Siphoviridae and Podoviridae. Annotation of functional genes revealed that during the under-ice period, the “Phages, Prophages, Transposable Elements and Plasmids” (27.4%) category represented the bulk of the virome. In the late spring period, it comprised 9.6% of the virome. We assembled contigs by two methods: Separately assembled in each virome or cross-assembled. A comparative analysis of the Baikal viromes with other aquatic environments indicated a distribution pattern by soil, marine and freshwater groups. Viromes of lakes Baikal, Michigan, Erie and Ontario form the joint World’s Largest Lakes clade

    Identification of important developmental genes.

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    <p>The method used to identify developmental genes is depicted as a flow chart (A). Blue boxes represent the wild type (AX4) and mutant strains with normal or delayed development as indicated. Red boxes represent transcripts whose abundance was not significantly altered by the mutations. Green boxes represent selected developmental genes. Ellipses represent the genomes of <i>D. discoideum</i> (yellow) and <i>D. purpureum</i> (purple) and the overlapping orthologs (not to scale). The volcano plot (B) shows the false discovery rate (FDR) of each transcript (y-axis, −log[FDR]) as a function of the difference in mRNA abundance between the median of all the normally developing mutants and the wild type (x-axis, log(mutant/WT) at 12-hours, when the gene expression was most variable across mutants. Each dot represents a gene, yellow dots represent genes that were identified as important for development and conserved between <i>D. discoideum</i> and <i>D. purpureum</i> (Gene set D), red dots represent genes that show little or no perturbation in expression during development (Gene set C – Gene set D), and black dots represent the rest of the genes. We validated the approach by examining the enrichment of developmental and non-developmental genes in gene sets C and D (C).</p
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