Stimulated Raman scattering in a non-eigenmode regime

Stimulated Raman scattering (SRS) in plasma in a non-eigenmode regime is studied theoretically and numerically. Different from normal SRS with the eigen electrostatic mode excited, the non-eigenmode SRS is developed at plasma density 0.25nc when the laser amplitude is larger than a certain threshold. To satisfy the phase-matching conditions of frequency and wavenumber, the excited electrostatic mode has a constant frequency around half of the incident light frequency, which is no longer the eigenmode of electron plasma wave. Both the scattered light and the electrostatic wave are trapped in plasma with their group velocities being zero. Super-hot electrons are produced by the non-eigen electrostatic wave. Our theoretical model is validated by particle-in-cell simulations. The SRS driven in this non-eigenmode regime is an important laser energy loss mechanism in the laser plasma interactions as long as the laser intensity is higher than

Plasma modulator for high-power intense lasers

A type of plasma-based optical modulator is proposed for the generation of broadband high-power laser pulses. Compared with normal optical components, plasma-based optical components can sustain much higher laser intensities. Here we illustrate via theory and simulation that a high-power sub-relativistic laser pulse can be self-modulated to a broad bandwidth over 100% after it passes through a tenuous plasma. In this scheme, the self-modulation of the incident picoseconds sub-relativistic pulse is realized via stimulated Raman forward rescattering in the quasi-linear regime, where the stimulated Raman backscattering is heavily dampened. The optimal laser and plasma parameters for this self-modulation have been identified. For a laser with asub-relativistic intensity of I ∼ 1017W/cm2, the time scale for the development of self-modulation is around 103 light periods when stimulated Raman forward scattering has been fully developed. Consequently, the spatial scale required for such a self-modulation is in the order of millimeters. For a tenuous plasma, the energy conversion efficiency of this self-modulation is around 90%. Theoretical predictions are verified by both one-dimensional and two-dimensional particle-in-cell simulations

Suppression of parametric instabilities in inhomogeneous plasma with multi-frequency light

The development of parametric instabilities in a large scale inhomogeneous plasma with an incident laser beam composed of multiple frequency components is studied theoretically and numerically. Firstly, theoretical analyses of the coupling between two laser beamlets with certain frequency difference δω 0 for parametric instabilities is presented. It suggests that the two beamlets will be decoupled when δω 0 is larger than certain thresholds, which are derived for stimulated Raman scattering, stimulated Brillouin scattering, and two plasmon decay, respectively. In this case, the parametric instabilities for the two beamlets develop independently and can be controlled at a low level provided the laser intensity for individual beamlet is low enough. Secondly, numerical simulations of parametric instabilities with two or more beamlets (N ∼ 20) have been carried out and the above theory model is validated. Simulations confirm that the development of parametric instabilities with multiple beamlets can be controlled at a low level, provided the threshold conditions for δω 0 is satisfied, even though the total laser intensity is as high as ∼10 15 W cm -2. With such a laser beam structure of multiple frequency components and total bandwidth of a few percentages (⪆4%ω 0), the parametric instabilities can be well-controlled

Absolute instability modes due to rescattering of stimulated Raman scattering in a large nonuniform plasma

Absolute instability modes due to rescattering of SRS in a large nonuniform plasma is studied theoretically and numerically. The backscattered light of convective SRS can be considered as a pump light with a finite bandwidth. The different frequency components of the backscattered light can be coupled to develop absolute stimulated Raman scattering (SRS) and two plasmon decay (TPD) instability near their quarter-critical densities via rescattering process. The absolute SRS mode develops a Langmuir wave with a high phase velocity about c/ √3 with c the light speed in vacuum. Given that most electrons are at low velocities in the linear stage, the absolute SRS mode grows with much weak Landau damping. When the interaction evolves into the nonlinear regime, the Langmuir wave can heat abundant electrons up to a few hundred keV. Our theoretical model is validated by particle-in-cell simulations. The absolute instabilities may play a considerable role for the indirect-drive experiments of inertial confined fusion

l-Tetrahydropalmatine, an Active Component of Corydalis yanhusuo W.T. Wang, Protects against Myocardial Ischaemia-Reperfusion Injury in Rats

l-Tetrahydropalmatine (l-THP) is an active ingredients of Corydalis yanhusuo W.T. Wang, which protects against acute global cerebral ischaemia-reperfusion injury. In this study, we show that l-THP is cardioprotective in myocardial ischaemia-reperfusion injury and examined the mechanism. Rats were treated with l-THP (0, 10, 20, 40 mg/kg b.w.) for 20 min before occlusion of the left anterior descending coronary artery and subjected to myocardial ischaemia-reperfusion (30 min/6 h). Compared with vehicle-treated animals, the infarct area/risk area (IA/RA) of l-THP (20, 40 mg/kg b.w.) treated rats was reduced, whilst l-THP (10 mg/kg b.w.) had no significant effect. Cardiac function was improved in l-THP-treated rats whilst plasma creatine kinase activity declined. Following treatment with l-THP (20 mg/kg b.w.), subunit of phosphatidylinositol 3-kinase p85, serine473 phosphorylation of Akt and serine1177 phosphorylation of endothelial NO synthase (eNOS) increased in myocardium, whilst expression of inducible NO synthase (iNOS) decreased. However, the expression of HIF-1α and VEGF were increased in I30 minR6 h, but decreased to normal level in I30 minR24 h, while treatment with l-THP (20 mg/kg b.w.) enhanced the levels of these two genes in I30 minR24 h. Production of NO in myocardium and plasma, activity of myeloperoxidase (MPO) in plasma and the expression of tumour necrosis factor-α (TNF-α) in myocardium were decreased by l-THP. TUNEL assay revealed that l-THP (20 mg/kg b.w.) reduced apoptosis in myocardium. Thus, we show that l-THP activates the PI3K/Akt/eNOS/NO pathway and increases expression of HIF-1α and VEGF, whilst depressing iNOS-derived NO production in myocardium. This effect may decrease the accumulation of inflammatory factors, including TNF-α and MPO, and lessen the extent of apoptosis, therefore contributing to the cardioprotective effects of l-THP in myocardial ischaemia-reperfusion injury

Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome : Insights from the LUNG SAFE study

Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study. Methods: In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence of hyperoxemia (PaO2 > 100 mmHg) on day 1, sustained (i.e., present on day 1 and day 2) hyperoxemia, or excessive oxygen use (FIO2 ≥ 0.60 during hyperoxemia). Results: Of 2005 patients that met the inclusion criteria, 131 (6.5%) were hypoxemic (PaO2 < 55 mmHg), 607 (30%) had hyperoxemia on day 1, and 250 (12%) had sustained hyperoxemia. Excess FIO2 use occurred in 400 (66%) out of 607 patients with hyperoxemia. Excess FIO2 use decreased from day 1 to day 2 of ARDS, with most hyperoxemic patients on day 2 receiving relatively low FIO2. Multivariate analyses found no independent relationship between day 1 hyperoxemia, sustained hyperoxemia, or excess FIO2 use and adverse clinical outcomes. Mortality was 42% in patients with excess FIO2 use, compared to 39% in a propensity-matched sample of normoxemic (PaO2 55-100 mmHg) patients (P = 0.47). Conclusions: Hyperoxemia and excess oxygen use are both prevalent in early ARDS but are most often non-sustained. No relationship was found between hyperoxemia or excessive oxygen use and patient outcome in this cohort. Trial registration: LUNG-SAFE is registered with ClinicalTrials.gov, NCT02010073publishersversionPeer reviewe

How Does E-commerce Industry Benefit from Big Data

In this paper, the benefits of applying big data in the industry of online retailing, with a focus on logistics distribution and precision marketing. The findings indicate that big data plays a crucial role in revolutionizing logistics distribution, enabling e-commerce companies to optimize their inventory management, delivery routes, and customer demand forecasting. This results in cost savings, improved efficiency, and enhanced customer satisfaction. Moreover, big data empowers precision marketing by providing deep customer insights, enabling effective segmentation, supporting dynamic pricing strategies, facilitating continuous optimization, and helping to prevent fraud. The findings also highlight the successful implementation of big data in leading Chinese e-commerce platforms, further emphasizing its benefits. Given that this research mainly centres around logistics distribution and precision marketing, its limitations is crucial to be acknowledged, with potential biases derived from the literature revie. Future research should address these limitations by exploring other aspects of the e-commerce industry, employing primary data collection methods, and investigating ethical implications and emerging technologies. By doing so, consumers can advance the understanding of big data’s role in driving innovation, improving operational efficiency, and fostering sustainable growth in the e-commerce industry

Study on radial suspension forces of bearingless permanent magnet slice motor based on accurate inductance model

An accurate mathematical model of radial suspension forces for a bearingless permanent magnet slice motor (BPMSM) is of great significance to levitate the rotor stably and to improve the control accuracy of radial suspension force. In this paper, after a brief introduction on the suspension principle of the BPMSM, the accurate inductance model of two sets of stator windings (torque windings and bearing windings) is deduced. Based on the accurate inductance model and taking rotor eccentricity into account, a complete and precise mathematical model of radial suspension forces of the BPMSM is obtained. In order to confirm the validity and feasibility of this mathematical model, the experiments are carried out on a 4kW prototype of the BPMSM. The experimental results show that the control system designed by using this method has high control accuracy of radial suspension force, strong capability of resisting disturbance, and good static and dynamic performance

Influence of flash treatment on pseudoelastic behaviour of biomedical Ti-25Nb-3Zr-3Mo-2Sn alloy

The effect of heat treatment on tensile properties, especially pseudoelastic behaviour of hot-rolled Ti-25Nb-3Zr-3Mo-2Sn (wt.%) alloy has been studied. The as-rolled alloy shows high strength due to the presence of nanoscale ω and α precipitates, but it suffers from limited ductility. The conventional solution plus ageing treatment improves the ductility, but it has an adverse effect on the psudoelastic properties. By applying flash treatment (500 °C for 2 min), the alloy is found to have not only balanced strength and ductility, but also improved psudoelastic properties, such as higher recovery strain and lower elastic modulus. The microstructural changes associated with the flash treatment are revealed