Advantages and Disadvantages of Distance Learning in Universities

Distance learning has always been of interest to researchers and scientists since its inception. In the current environment of the modern world, this type of training is becoming increasingly popular despite the large number of its opponents. Of course, it can not be called absolutely perfect, because it requires the availability of impeccable technical equipment of educational institutions, uninterrupted Internet, a perfectly working portal and an appropriate platform for such training. The Article is devoted to the description of the advantages and disadvantages of learning in higher education. In the context of modern realities, distance learning is spreading faster and faster in all areas of our life, in particular in the educational process. However, it cannot completely replace traditional learning. There is no doubt that distance learning has a number of advantages, but in view of the lack of uninterrupted Internet outside of large cities, and sometimes its complete absence, there are many problems regarding the organization of this type of training. It should also be noted that distance learning requires a lot of self-discipline of a person and the ability to independently study a particular subject. Therefore, before making a decision to completely replace traditional distance learning, it is necessary to weigh all the pros and cons, remembering that distance learning cannot be perfect enough and that it cannot be a worthy replacement for traditional learning

Advantages and Disadvantages of Distance Learning in Universities

Distance learning has always been of interest to researchers and scientists since its inception. In the current environment of the modern world, this type of training is becoming increasingly popular despite the large number of its opponents. Of course, it can not be called absolutely perfect, because it requires the availability of impeccable technical equipment of educational institutions, uninterrupted Internet, a perfectly working portal and an appropriate platform for such training. The Article is devoted to the description of the advantages and disadvantages of learning in higher education. In the context of modern realities, distance learning is spreading faster and faster in all areas of our life, in particular in the educational process. However, it cannot completely replace traditional learning. There is no doubt that distance learning has a number of advantages, but in view of the lack of uninterrupted Internet outside of large cities, and sometimes its complete absence, there are many problems regarding the organization of this type of training. It should also be noted that distance learning requires a lot of self-discipline of a person and the ability to independently study a particular subject. Therefore, before making a decision to completely replace traditional distance learning, it is necessary to weigh all the pros and cons, remembering that distance learning cannot be perfect enough and that it cannot be a worthy replacement for traditional learning.El artículo está dedicado a la descripción de las ventajas y desventajas del aprendizaje en la educación superior. En el contexto de las realidades modernas, la educación a distancia se está extendiendo cada vez más rápido en todos los ámbitos de nuestra vida, en particular en el proceso educativo. Sin embargo, no puede reemplazar completamente el aprendizaje tradicional. No cabe duda de que la educación a distancia tiene una serie de ventajas, pero ante la falta de Internet ininterrumpida fuera de las grandes ciudades, y en ocasiones su ausencia total, existen muchos problemas en la organización de este tipo de formación. También debe tenerse en cuenta que el aprendizaje a distancia requiere mucha autodisciplina de una persona y la capacidad de estudiar de forma independiente un tema en particular. Por lo tanto, antes de tomar la decisión de reemplazar completamente el aprendizaje a distancia tradicional, es necesario sopesar todos los pros y los contras, recordando que el aprendizaje a distancia no puede ser lo suficientemente perfecto y que no puede ser un reemplazo digno del aprendizaje tradicional

Influence of Silver Nanoparticles on the Growth of Ascitic and Solid Ehrlich Adenocarcinoma: Focus on Copper Metabolism

The link between copper metabolism and tumor progression motivated us to use copper chelators for suppression of tumor growth. We assume that silver nanoparticles (AgNPs) can be used for lowering bioavailable copper. Our assumption is based on the ability of Ag(I) ions released by AgNPs in biological media and interfere with Cu(I) transport. Intervention of Ag(I) into copper metabolism leads to the replacement of copper by silver in ceruloplasmin and the decrease in bioavailable copper in the bloodstream. To check this assumption, mice with ascitic or solid Ehrlich adenocarcinoma (EAC) were treated with AgNPs using different protocols. Copper status indexes (copper concentration, ceruloplasmin protein level, and oxidase activity) were monitored to assess copper metabolism. The expression of copper-related genes was determined by real-time PCR in the liver and tumors, and copper and silver levels were measured by FAAS. Intraperitoneal AgNPs treatment beginning on the day of tumor inoculation enhanced mice survival, reduced the proliferation of ascitic EAC cells, and suppressed the activity of HIF1α, TNF-α and VEGFa genes. Topical treatment by the AgNPs, which was started together with the implantation of EAC cells in the thigh, also enhanced mice survival, decreased tumor growth, and repressed genes responsible for neovascularization. The advantages of silver-induced copper deficiency over copper chelators are discussed

Bacterial Communities of <i>Lamiacea</i> L. Medicinal Plants: Structural Features and Rhizosphere Effect

Bacterial communities associated with medicinal plants are an essential part of ecosystems. The rhizosphere effect is rather important in the cultivation process. The purpose of the study was to analyze the rhizosphere effect of oregano (Origanum vulgare L.), peppermint (Mentha piperita L.), thyme (Thymus vulgaris L.), creeping thyme (Thymus serpillum L.) and sage (Salvia officinalis L.). To estimate the quantity of 16S bacteria ribosomal genes, qPCR assays were used. To compare bacterial communities’ structure of medicinal plants rhizosphere with bulk soil high-throughput sequencing of the 16S rRNA targeting variable regions V3–V4 of bacteria was carried out. The highest bacterial abundance was associated with T. vulgaris L., M. piperita L. and S. officinalis L., and the lowest was associated with the O. vulgare L. rhizosphere. Phylum Actinobacteriota was predominant in all rhizosphere samples. The maximum bacterial α-diversity was found in S. officinalis L. rhizosphere. According to bacterial β-diversity calculated by the Bray–Curtis metric, T. vulgaris L. root zone significantly differed from bulk soil. The rhizosphere effect was positive to the Myxococcota, Bacteroidota, Verrucomicrobiota, Proteobacteria and Gemmatimonadota