ELECTRICITY GENERATION CHARACTERISTICS OF AN ANAEROBIC FLUIDIZED BED MICROBIAL FUEL CELL

Anaerobic fluidized bed microbial fuel cell (AFBMFC) was developed to investigate the effect of fluidization behaviors on the electrogenesis capacity. Waste water and active carbon were used as liquid and solid phase, respectively. The fuel cell was started up successfully using anaerobic activated sludge as inoculums. The power density is increased with increasing circular liquid velocity up to 450 mW·m-2. High COD remove rate reached 93% after five days operation. Meanwhile, the effects of cathode area on the electrogenesis capacity of AFB MFC were also investigated

Online monitoring method of mine-used high voltage cable insulatio

In order to monitor insulation condition of mine-used high voltage cable in real time, an online monitoring method of mine-used high voltage cable insulation based on wide area measurement system(WAMS) was proposed. In the method, real-time voltage and current of cable ends are obtained synchronously by use of WAMS, and insulation resistance and equivalent capacitance of cable are derived through establishment of equivalent circuit model of cable to ground, so as to realize dynamic monitoring of cable insulation condition. The simulation results show that measurement error of the method decreases with increase of cable insulation deterioration, which meets precision requirement of online monitoring of mine-used high voltage cable insulation

Supported Liquid Membranes Based on Bifunctional Ionic Liquids for Selective Recovery of Gallium

In this work, separation and recovery of gallium from aqueous solutions was examined using acid-base bifunctional ionic liquids (Bif-ILs) in both solvent extraction and supported liquid membrane (SLM) processes. The influence of a variety of parameters, such as feed acidity, extractant concentration and metal concentration on the solvent extraction behavior were evaluated. The slope method combined with FTIR spectroscopy was utilized to determine possible extraction mechanisms. The SLM containing Bif-ILs demonstrated highly selective facilitated transport of 96.2% Ga(III) from feed to stripping solution after optimization. During the evaluation of the separation performance of SLM for the transport of Ga(III), in the presence of Al(III), Mg(II), Cu(II) and Fe(II), 88.5% Ga(III) could be transported with only 6% Fe(II) and a nil quantity of other metals co-transported. SLM exhibited excellent long-time stability in five repeated transport cycles. Highly selective transport and separation performance was achieved using the SLM containing Bif-ILs, indicating considerable potential for application in Ga(III) recovery

A novel quantification method for analysis of twenty natural amino acids in human serum based on N-phosphorylation labeling using reversed-phase liquid chromatography-tandem mass spectrometry

A novel method based on the strategy of N-phosphorylation labeling is described for quantification of twenty natural amino acids in human serum by reversed-phase liquid chromatography-electrospray tandem mass spectrometry (RP-LC/ESI-MS). The derivatization reaction was easily performed in one-pot reaction under mild conditions within 30. min. The reaction mixture was then evaporated to dryness, redissolved, desalted by C18 SPE. The twenty N-phosphoryl amino acids were separated on an RP-C18 column within 20. min by isocratic elution (0.1% formic acid-acetonitrile, v/v 7:3). At the same time, multiple reaction monitoring (MRM) MS enabled quantitation of twenty natural amino with the LOD of 0.0005-0.15. μM and LOQ of 0.0020-0.5. μM in human serum. The linear range was from 0.025 to 25. μM (except Cys and Trp) with R>. 0.99. The recovery range was determined to be 85.5-117.4% with the relative standard deviation (RSD) in the range of 1.3-13.9%. All twenty amino acids were successfully detected in human serum samples with the concentration from 5.7 to 577.9. μM, which indicates potential of the developed method for determination of amino acids in complex biological samples, hence for screening of amino acid metabolite related diseases. ? 2014 Elsevier B.V

Efficacy of adjuvant TACE on the prognosis of patients with HCC after hepatectomy: a multicenter propensity score matching from China

Abstract Background The survival benefit of adjuvant transarterial chemoembolization (TACE) in patients with hepatectomy for hepatocellular carcinoma (HCC) after hepatectomy remains controversial. We aimed to investigate the survival efficacy of adjuvant TACE after hepatectomy for HCC. Methods 1491 patients with HCC who underwent hepatectomy between January 2018 and September 2021 at four medical centers in China were retrospectively analyzed, including 782 patients who received adjuvant TACE and 709 patients who did not receive adjuvant TACE. Propensity score matching (PSM) (1:1) was performed to minimize selection bias, which balanced the clinical characteristics of the two groups. Results A total of 1254 patients were enrolled after PSM, including 627 patients who received adjuvant TACE and 627 patients who did not receive adjuvant TACE. Patients who received adjuvant TACE had higher disease-free survival (DFS, 1- ,2-, and 3-year: 78%-68%-62% vs. 69%-57%-50%, p < 0.001) and overall survival (OS, 1- ,2-, and 3-year: 96%-88%-80% vs. 90%-77%-66%, p < 0.001) than those who did not receive adjuvant TACE (Median DFS was 39 months). Among the different levels of risk factors affecting prognosis [AFP, Lymphocyte-to-monocyte ratio, Maximum tumor diameter, Number of tumors, Child-Pugh classification, Liver cirrhosis, Vascular invasion (imaging), Microvascular invasion, Satellite nodules, Differentiation, Chinese liver cancer stage II-IIIa], the majority of patients who received adjuvant TACE had higher DFS or OS than those who did not receive adjuvant TACE. More patients who received adjuvant TACE accepted subsequent antitumor therapy such as liver transplantation, re-hepatectomy and local ablation after tumor recurrence, while more patients who did not receive adjuvant TACE accepted subsequent antitumor therapy with TACE after tumor recurrence (All p < 0.05). Conclusions Adjuvant TACE may be a potential way to monitor early tumor recurrence and improve postoperative survival in patients with HCC

Synthesis and biological evaluation of novel bromophenol derivatives as carbonic anhydrase inhibitors

Here, we provide an alternative synthesis of the natural bromophenol 3,4-dibromo-5-(2,3-dibromo-4,5-dihydroxybenzyl)-6-(ethoxymethyl) benzene-1,2-diol (3) and the first synthesis of (4,5-dihydroxy-2methylphenyl)( 3,4-dihydroxyphenyl) methanone (18) and its brominated derivatives 19-21. The compounds were characterized and tested against the two most studied members of the pH regulatory enzyme family, carbonic anhydrase (CA). The inhibitory potencies of the novel compounds and two natural bromophenols 2, 3 were analyzed at the human isoforms hCA I and hCA II as targets and the K-I values were calculated. The K-I values of the novel compounds were measured in the range of 13.7-32.7 mu M for the hCA I isozyme and 0.65-1.26 mu M for the hCA II isozyme. The structurally related compound 14 was also tested in order to understand the structure-activity relationship, and the clinically used sulfonamide acetazolamide (AZA) was tested for comparison reasons. All of the compounds exhibited competitive inhibition with 4-nitrophenylacetate as substrate. The compounds showed strong inhibitory activity against hCA I, being more effective as compared to the clinically used AZA (K-I: 36.2 mu M), but rather less activity against hCA II