Local generation of hydrogen for enhanced photothermal therapy.

By delivering the concept of clean hydrogen energy and green catalysis to the biomedical field, engineering of hydrogen-generating nanomaterials for treatment of major diseases holds great promise. Leveraging virtue of versatile abilities of Pd hydride nanomaterials in high/stable hydrogen storage, self-catalytic hydrogenation, near-infrared (NIR) light absorption and photothermal conversion, here we utilize the cubic PdH0.2 nanocrystals for tumour-targeted and photoacoustic imaging (PAI)-guided hydrogenothermal therapy of cancer. The synthesized PdH0.2 nanocrystals have exhibited high intratumoural accumulation capability, clear NIR-controlled hydrogen release behaviours, NIR-enhanced self-catalysis bio-reductivity, high NIR-photothermal effect and PAI performance. With these unique properties of PdH0.2 nanocrystals, synergetic hydrogenothermal therapy with limited systematic toxicity has been achieved by tumour-targeted delivery and PAI-guided NIR-controlled release of bio-reductive hydrogen as well as generation of heat. This hydrogenothermal approach has presented a cancer-selective strategy for synergistic cancer treatment

Modifying Photos Based on Photo Capture from Multiple Device Cameras

This disclosure describes techniques to modify photos based on additional photos captured from multiple cameras of a device. A user captures a main photo of a scene with one camera of a device, and, in the background, additional photo(s) are automatically captured by other camera(s) of the device. Portions from the additional photos can be used to modify the main photo. For example, the view and/or aspect ratio of the captured photo can be modified to show portions of the scene that are not present in the main photo. This saves the user time and effort by automatically capturing additional photos of a scene and providing a range of editing options that take advantage of the additional photos

Genome divergence and dynamics in the thin-tailed desert sheep from Sudan

With climate change bound to affect food and feed production, emphasis will shift to resilient and adapted indigenous livestock to sustain animal production. However, indigenous livestock comprise several varieties, strains and ecotypes whose genomes are poorly characterized. Here, we investigated genomic variation in an African thin-tailed Desert Sheep sampled in Sudan, using 600K genotype data generated from 92 individuals representing five ecotypes. We included data from 18 fat-tailed and 45 thin-tailed sheep from China, to investigate shared ancestry and perform comparative genomic analysis. We observed a clear genomic differentiation between the African thin-tailed Desert Sheep and the Chinese thin-tailed and fat-tailed sheep, suggesting a broad genetic structure between the fat-tailed and thin-tailed sheep in general, and that at least two autosomal gene pools comprise the genome profile of the thin-tailed sheep. Further analysis detected two distinct genetic clusters in both the African thin-tailed Desert Sheep and the Chinese thin-tailed sheep, suggesting a fine-scale and complex genome architecture in thin-tailed sheep. Selection signature analysis suggested differences in adaptation, production, reproduction and morphology likely underly the fine-scale genetic structure in the African thin-tailed Desert Sheep. This may need to be considered in designing breeding programs and genome-wide association studies

Federal Recovery Funds Allocated

Figure S1. Overview of the informatics pipeline used to the identify lincRNAs in goat. (PDF 216 kb

The Importance of Learning Islamic History and Civilization of Malaysia in the Building of Human Capital and Identity of the Muslim Society in Malaysia

AbstractThe purpose of this research is to study the importance of learning Islamic History and Civilization in Malaysia for human capital building and identification of the muslim society in Malaysia. Its aim is to clarify the importance of this course, specifically at the Department of Arabic Studies and Islamic Civilization, and the need to produce graduates who are conversant in this field in order that they may utilise it in their lives regardless of whichever field they venture into. This study uses the library research method by analysis and evaluation with an argumentative as well as narrative approach. The results of study finds that knowledge and conversance in this field is integral in the formation of human capital and identity of the muslim society in Malaysia. Knowledge and conversance in this field would enable Malays to know the ‘true’ history of the muslim ummah in Malaysia. This knowledge is crucial to help them form and build a Malay-muslim generation in Malaysia, strongly attached to Malay traditions which have once brought the muslims to the pinnacle of success