9,650 research outputs found
Both ion channels and calcium signals regulate proliferation in human adult mesenchymal stem cells from bone marrow
BACKGROUND: It has been recognized that human bone marrow-derived mesenchymal stem cells (MSCs) are present within the bone marrow cavity and serve as a reservoir for the ...postprintThe 9th Annual Meeting of the International Society for Stem Cell Research (ISSCR 2011), Toronto, Canada, 15-18 June 2011. In Thursday Poster Abstracts of ISSCR, 2011, p. 156, poster board no. 301
An improved LDA approach
2004-2005 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe
Band structures and transport properties of zigzag graphene nanoribbons with antidot arrays
We study the band and transport features of zigzag graphene nanoribbon with an antidot lattice. It is found that an antidot lattice could turn semi-metal graphene into a semiconductor. The size of the band gap can be tuned by the position of the antidots and the distance D between the two nearest antidots. For a finite superlattice with N antidots and a large D, a group of (N - 1) splitting resonant peaks and transmission-blockade regions appear alternately in the conductance spectrum. This indicates the formation of minibands and minigaps. In addition, Fano resonances can be observed when the antidots are localized near one edge of the nanoribbon. These features provide potential applications for graphene-based electronic and optoelectronic devices. © 2010 IOP Publishing Ltd.postprin
Regulation of cell proliferation by ion channels in human mesenchymal stem cells
Oral presentationpublished_or_final_versionThe 15th Annual Research Conference of the Department of Medicine, The University of Hong Kong, Hong Kong, 16 January 2010. In Hong Kong Medical Journal, 2010, v. 16, suppl. 1, p. 65, abstract no. 11
Highly reproducible SERS substrate based on polarization-free Ag nanoparticles decorated SiO2/Si core-shell nanowires array
SiO2/Si core-shell nanowires array coated with gap-rich silver nanoparticles were demonstrated as a highly reproducible surface-enhanced Raman scattering (SERS) substrate. SERS detection of a relative standard deviation of 8% for 10−4 M R6G with a spot size of ∼2 μm and 900 spots over an area of 150 × 150 μm2 was reported. The high reproducibility is ascribed to the polarization-independent electrical field distribution among three-dimensional nanowire structure with an optimized thickness of SiO2 shell layer.published_or_final_versio
Semi-Supervised Overlapping Community Finding based on Label Propagation with Pairwise Constraints
Algorithms for detecting communities in complex networks are generally
unsupervised, relying solely on the structure of the network. However, these
methods can often fail to uncover meaningful groupings that reflect the
underlying communities in the data, particularly when those structures are
highly overlapping. One way to improve the usefulness of these algorithms is by
incorporating additional background information, which can be used as a source
of constraints to direct the community detection process. In this work, we
explore the potential of semi-supervised strategies to improve algorithms for
finding overlapping communities in networks. Specifically, we propose a new
method, based on label propagation, for finding communities using a limited
number of pairwise constraints. Evaluations on synthetic and real-world
datasets demonstrate the potential of this approach for uncovering meaningful
community structures in cases where each node can potentially belong to more
than one community.Comment: Fix table
Rapid detection of adulterated drugs in herbal dietary supplements by wooden-tip electrospray ionization mass spectrometry
Version of RecordPublishe
Six SNPs and a TTG indel in sheep desmoglein 4 gene are in complete linkage disequilibrium
Desmoglein 4 (DSG4) plays an important role in the regulation of growth and differentiation of hair follicles in mammals. In this study, a 755 bp long segment of DSG4 was screened in 544 sheep sampled from nine Chinese indigenous breeds and two Western breeds using PCR-SSCP assay with three different pairs of primers. Two of the three fragments showed polymorphisms with genotypes defined as AA, AB, BB and BC, and DD, DE, and EE, respectively. Interestingly, polymorphisms in these two fragments were in strong linkage disequilibrium. Only three haplotypes were found, of which haplotype AD determined by alleles A and D was the major one in all breeds, while haplotype BE was only found in Chinese breeds that possess divergent frequencies ranging from 0.02 to 0.43; haplotype CD was very rare and present in only one Chinese sheep. Sequences of the three haplotypes showed seven single nucleotide polymorphisms (SNPs) and a TTG insertion/deletion (indel), leading to five amino acid substitutions and a glycine indel. Our study provides valuable genetic markers in evaluating the impact of the DSG4 gene on wool traits in sheep.Key words: Sheep, DSG4 gene, single-strand conformational polymorphism (SSCP), variation, linkage disequilibrium
Bio-Inspired Aggregation Control of Carbon Nanotubes for Ultra-Strong Composites
High performance nanocomposites require well dispersion and high alignment of
the nanometer-sized components, at a high mass or volume fraction as well.
However, the road towards such composite structure is severely hindered due to
the easy aggregation of these nanometer-sized components. Here we demonstrate a
big step to approach the ideal composite structure for carbon nanotube (CNT)
where all the CNTs were highly packed, aligned, and unaggregated, with the
impregnated polymers acting as interfacial adhesions and mortars to build up
the composite structure. The strategy was based on a bio-inspired aggregation
control to limit the CNT aggregation to be sub 20--50 nm, a dimension
determined by the CNT growth. After being stretched with full structural
relaxation in a multi-step way, the CNT/polymer (bismaleimide) composite
yielded super-high tensile strengths up to 6.27--6.94 GPa, more than 100%
higher than those of carbon fiber/epoxy composites, and toughnesses up to
117--192 MPa. We anticipate that the present study can be generalized for
developing multifunctional and smart nanocomposites where all the surfaces of
nanometer-sized components can take part in shear transfer of mechanical,
thermal, and electrical signals
Particle size distribution of tin powder produced by centrifugal atomisation using rotating cups
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