Twist-3 light-cone distribution amplitudes of the scalar mesons within the QCD sum rules and their application to the B→SB \to S transition form factors

We investigate the twist-3 light-cone distribution amplitudes (LCDAs) of the scalar mesons $a_0$, $K^{\ast}_0$ and $f_0$ within the QCD sum rules. The QCD sum rules are improved by a consistent treatment of the sizable $s$-quark mass effects within the framework of the background field approach. Adopting the valence quark component $(\bar{q}_1 q_2)$ as the dominant structure of the scalar mesons, our estimation for their masses are close to the measured $a_0(1450)$, $K^{\ast}_0(1430)$ and $f_0(1710)$. From the sum rules, we obtain the first two non-zero moments of the twist-3 LCDAs $\phi^{s,\sigma}_{a_0}$: $\langle \xi_{s,a_0}^{2(4)} \rangle=0.369 \;(0.245)$ and $\langle \xi_{\sigma,a_0}^{2(4)} \rangle=0.203 \;(0.093)$; those of the twist-3 LCDAs $\phi_{K^*_0}^{s,\sigma}$: $\langle \xi_{s,K^{\ast}_0}^{1(2)} \rangle =0.004\;(0.355)$ and $\langle \xi_{\sigma,K^{\ast}_0}^{1(2)} \rangle =0.018\;(0.207)$; and those of the twist-3 LCDAs $\phi_{f_0}^{s,\sigma}$: $\langle \xi_{s,f_0}^{2(4)} \rangle=0.335 \;(0.212)$ and $\langle \xi_{\sigma,f_0}^{2(4)} \rangle=0.196 \; (0.088)$, respectively. As an application of those twist-3 LCDAs, we study the $B \to S$ transition form factors by introducing proper chiral currents into the correlator, which is constructed such that the twist-3 LCDAs give dominant contribution and the twist-2 LCDAs make negligible contribution. Our results of the $B \to S$ transition form factors at the large recoil region $q^2 \simeq 0$ are consistent with those obtained in the literature, which inversely shows the present twist-3 LCDAs are acceptable.Comment: 14 pages, 12 figures, 7 table

The Higgs boson inclusive decay channels H→bbˉH \to b\bar{b} and H→ggH \to gg up to four-loop level

The principle of maximum conformality (PMC) has been suggested to eliminate the renormalization scheme and renormalization scale uncertainties, which are unavoidable for the conventional scale setting and are usually important errors for theoretical estimations. In this paper, by applying PMC scale setting, we analyze two important inclusive Standard Model Higgs decay channels, $H\rightarrow b\bar{b}$ and $H\rightarrow gg$, up to four-loop and three-loop levels accordingly. After PMC scale setting, it is found that the conventional scale uncertainty for these two channels can be eliminated to a high degree. There is small residual initial scale dependence for the Higgs decay widths due to unknown higher-order $\{\beta_i\}$-terms. Up to four-loop level, we obtain $\Gamma(H\rightarrow b\bar{b}) = 2.389\pm0.073 \pm0.041$ MeV and up to three-loop level, we obtain $\Gamma(H\rightarrow gg) = 0.373\pm0.030$ MeV, where the first error is caused by varying $M_H=126\pm4$ GeV and the second error for $H\to b\bar{b}$ is caused by varying the $\overline{\rm MS}$-running mass $m_b(m_b)=4.18\pm0.03$ GeV. Taking $H\to b\bar{b}$ as an example, we present a comparison of three BLM-based scale setting approaches, e.g. the PMC-I approach based on the PMC-BLM correspondence, the $R_\delta$-scheme and the seBLM approach, all of which are designed to provide effective ways to identify non-conformal $\{\beta_i\}$-series at each perturbative order. At four-loop level, all those approaches lead to good pQCD convergence, they have almost the same pQCD series, and their predictions are almost independent on the initial renormalization scale. In this sense, those approaches are equivalent to each other.Comment: 14 pages, 7 figures. References updated and discussions improved. To be published in Eur.Phys.J.

Amentotaxus × hybridia (Taxaceae), a new natural Amentotaxus hybrid from southeast Yunnan province, China

During floristic surveys of Taxaceae in Hekou County, Yunnan Province, China, a putative natural hybrid between A. yunnanensis H.L. Li and A. hekouensis L.M. Gao was collected. Morphological and molecular evidence confirms its status as a natural hybrid. Amentotaxus × hybridia L.M. Gao has linear or linear-lanceolate leaves 6–13 cm × 1.0–1.5 cm, white stomatal bands with 34–40 rows on abaxial side, 2.5–3.5 mm, slightly wider than leaf margins; 3–6 seeds borne at the base of the branchlet, peduncle 1.3–1.6 cm long with 3–4 rows of persistent basal bracts

参地糖脉宁汤对实验性2型糖尿病大鼠肝细胞脂肪变的效应*

Objective: To evaluate effects of Shendi Tang Maining Decoction on steatosis of hepatocyte in type 2 diabetes mellitus. Methods: Type 2 diabetes was induced, in female Wistar rats, by intraperitoneal injection of streptozotocin (25 mg/kg BW), fed with high sucrose and high lipid food. Animals were divided into 2 groups, type 2 diabetes control group (T2DMC group; n=12), type 2 diabetes invention group (T2DMI group; n=12). The age and sex matched Wistar rats served as normal control group (NC group, n=12). The rats of T2DMI group were fed with Shendi Tang Maining Decoction [active pharmaceutical ingredient 5mg/(kg BW•d)]. The rat of NC group and T2DMC were fed with cool boiled water. Results: Steatosis of hepatocyte was significant more in every group of type 2 diabetes than NC group (P<0.01). Steatosis of hepatocyte was significant less in T2DNI group than T2DMC group （P<0.01）. Hepatic PAS stain was significant lighter in every group of type 2 diabetes than NC group (P<0.01). Hepatic PAS stain was significant darker in T2DNI group than T2DMC group（P<0.01）. Conclusion: Shendi Tang Maining Decoction can ameliorate steatosis and glycogen quantity of hepatocyte in type 2 diabetes mellitus.目的  评价参地糖脉宁汤对2型糖尿病时肝细胞脂肪变的效应。方法  用小剂量STZ (25 mg/kg BW) 雌性Wistar大鼠腹腔内注射加含高糖和高脂饲料喂养造成实验性2型糖尿病模型，分为二组，2型糖尿病对照组（T2DMC组,n＝12），2型糖尿病干预组（T2DMI组,n＝12）。相同鼠龄的雌性Wistar大鼠作为正常对照组（NC组，n＝12）。T2DMI组用参地糖脉宁汤[原药5g/（kg WD·d）]灌胃；NC组、T2DMC组用凉开水灌胃。观察参地糖脉宁汤对2型糖尿病时肝细胞脂肪变的效应。结果  T2DM各组大鼠肝细胞脂肪变显著多于NC组（P＜0.01），而T2DMI组肝细胞脂肪变显著少于T2DMC组。T2DM各组大鼠肝PAS染色密度显著低于NC组（P＜0.01），而T2DMI组肝细胞PAS染色深度显著高于T2DMC组。结论  参地糖脉宁汤能改善2型糖尿病时的肝细胞脂肪变和糖原含量

The New Application of UHPLC-DAD-TOF/MS in Identification of Inhibitors on β-Amyloid Fibrillation From Scutellaria baicalensis

Literary evidence depicts that aggregated β-amyloid (Aβ) leads to the pathogenesis of Alzheimer’s disease (AD). Although many traditional Chinese medicines (TCMs) are effective in treating neurodegenerative diseases, there is no effective way for identifying active compounds from their complicated chemical compositions. Instead of using a traditional herbal separation method with low efficiency, we herein apply UHPLC-DAD-TOF/MS for the accurate identification of the active compounds that inhibit the fibrillation of Aβ (1-42), via an evaluation of the peak area of individual chemical components in chromatogram, after incubation with an Aβ peptide. Using the neuroprotective herbal plant Scutellaria baicalensis (SB) as a study model, the inhibitory effect on Aβ by its individual compounds, were validated using the thioflavin-T (ThT) fluorescence assay, biolayer interferometry analysis, dot immunoblotting and native gel electrophoresis after UHPLC-DAD-TOF/MS analysis. The viability of cells after Aβ (1-42) incubation was further evaluated using both the tetrazolium dye (MTT) assay and flow cytometry analysis. Thirteen major chemical components in SB were identified by UHPLC-DAD-TOF/MS after incubation with Aβ (1–42). The peak areas of two components from SB, baicalein and baicalin, were significantly reduced after incubation with Aβ (1–42), compared to compounds alone, without incubation with Aβ (1–42). Consistently, both compounds inhibited the formation of Aβ (1–42) fibrils and increased the viability of cells after Aβ (1–42) incubation. Based on the hypothesis that active chemical components have to possess binding affinity to Aβ (1–42) to inhibit its fibrillation, a new application using UHPLC-DAD-TOF/MS for accurate identification of inhibitors from herbal plants on Aβ (1–42) fibrillation was developed

Dynamic prostatic and laser-ablated lesion volume change after transperineal laser ablation in canine: preliminary observation and its clinical significance.

AIM: The purpose of this study is to observe the volume change of prostate and laser-ablated lesions in the canine and to explore the mechanism and clinical significance through histopathology. MATERIALS AND METHODS: Transperineal laser ablation (TPLA) was performed under the guidance of transrectal ultrasound (TRUS) in eight canines. Two canines were sacrificed 1 day and 1 week after TPLA, respectively. The remaining six canines were sacrificed after finishing transrectal contrast-enhanced ultrasound (TR-CEUS) at three phases. RESULTS: The prostatic volumes immediately following TPLA and 1 week later were larger than before TPLA (20.1 ± 3.9 vs 17.1 ± 3.8 ml; 21.7 ± 3.6 vs 17.1 ± 3.8 ml, p \u3c 0.05), but 1 month later, returned to the preoperative level (17.4 ± 3.2 ml). At three time points, the mean volumes of laser-ablated lesions at 3 W/600 J were 0.6 ± 0.2, 1.1 ± 0.4, and 1.7 ± 0.5 ml, respectively, while those of laser-ablated lesions at 3 W/1200 J were 1.2 ± 0.2, 1.6 ± 0.3, and 2.2 ± 0.5 ml, respectively. The mean volumes of laser-ablated lesions increased significantly over time after TPLA (p \u3c 0.050). CONCLUSION: The prostate volume transient enlarges after TPLA, which prompts for clinical application that it should prolong appropriately the duration of urinary catheterization to avoid acute urinary retention. Many inflammatory cells were observed in the laser-ablated lesions and adjacent normal prostate parenchyma through histopathology. It is speculated that the inflammatory response is involved in the progression of tissue damage