Measurement of charm and bottom production from semileptonic hadron decays in p + p collisions at √s = 200 GeV

Measurements of the differential production of electrons from open-heavy-flavor hadrons with charm- and bottom-quark content in p+p collisions at √s=200  GeV are presented. The measurements proceed through displaced-vertex analyses of electron tracks from the semileptonic decay of charm and bottom hadrons using the PHENIX silicon-vertex detector. The relative contribution of electrons from bottom decays to inclusive heavy-flavor-electron production is found to be consistent with fixed-order-plus-next-to-leading-log perturbative-QCD calculations within experimental and theoretical uncertainties. These new measurements in p+p collisions provide a precision baseline for comparable forthcoming measurements in A+A collisions

The spatiotemporal variation and control mechanism of surface pCO2 in winter in Jiaozhou Bay, China

In many mid-latitude coastal waters during winter months, in addition to temperature, the large change in biogeochemical processes often influence and complicate the surface partial pressure of CO2 (pCO2). Based on the hydrological and carbonate parameters in seven cruises, this study analysed the evolution process and explored the control mechanism of the surface pCO2 in Jiaozhou Bay, China, from December to March. The results showed that the pCO2 ranged from 157 μatm to 647 μatm, and the bay represented a sink for atmospheric CO2 (-3.8 mmol m-2 d-1) in the whole winter. The non-temperature processes were the dominant factors affecting intra-winter pCO2 variation. In December, the bay was dominated by aerobic respiration and acted as a CO2 source (3.0 mmol m-2 d-1). From early January to late February, however, the vigorous growth of cold algae caused strong primary production, and the bay presented as a CO2 sink (from -6.4 mmol m-2 d-1 in early January to -15.5 mmol m-2 d-1 in late February). In March, primary production weakened and the effects of the CaCO3 precipitation appeared, and the strength of the CO2 sink was obviously weakened (-1.1 mmol m-2 d-1). Meanwhile, the water temperature decreased gradually from December to late January and then increased until March, and it further expanded the variation range of pCO2. Our results highlight the obvious source/sink change in mid-latitude seawater CO2 in winter, while more field observations are still needed to further understand the complicated biogeochemical processes and its influence on seawater pCO2

Measurement of inclusive Br(B+->DX) through Full-Event Interpretation using Belle II Data

Measurement of inclusive Br(B+->DX) through Full-Event Interpretation using Belle II Data2 year

Flow cytometric immunobead assay for quantitative detection of platelet autoantibodies in immune thrombocytopenia patients

Abstract Background Platelet autoantibody detection is critical for immune thrombocytopenia (ITP) diagnosis and prognosis. Therefore, we aimed to establish a quantitative flow cytometric immunobead assay (FCIA) for ITP platelet autoantibodies evaluation. Methods Capture microbeads coupled with anti-GPIX, -GPIb, -GPIIb, -GPIIIa and P-selectin antibodies were used to bind the platelet-bound autoantibodies complex generated from plasma samples of 250 ITP patients, 163 non-ITP patients and 243 healthy controls, a fluorescein isothiocyanate (FITC)-conjugated secondary antibody was the detector reagent and mean fluorescence intensity (MFI) signals were recorded by flow cytometry. Intra- and inter-assay variations of the quantitative FCIA assay were assessed. Comparisons of the specificity, sensitivity and accuracy between quantitative and qualitative FCIA or monoclonal antibody immobilization of platelet antigen (MAIPA) assay were performed. Finally, treatment process was monitored by our quantitative FCIA in 8 newly diagnosed ITPs. Results The coefficient of variations (CV) of the quantitative FCIA assay were respectively 9.4, 3.8, 5.4, 5.1 and 5.8% for anti-GPIX, -GPIb, -GPIIIa, -GPIIb and -P-selectin autoantibodies. Elevated levels of autoantibodies against platelet glycoproteins GPIX, GPIb, GPIIIa, GPIIb and P-selectin were detected by our quantitative FCIA in ITP patients compared to non-ITP patients or healthy controls. The sensitivity, specificity and accuracy of our quantitative assay were respectively 73.13, 81.98 and 78.65% when combining all 5 autoantibodies, while the sensitivity, specificity and accuracy of MAIPA assay were respectively 41.46, 90.41 and 72.81%. Conclusions A quantitative FCIA assay was established. Reduced levels of platelet autoantibodies could be confirmed by our quantitative FCIA in ITP patients after corticosteroid treatment. Our quantitative assay is not only good for ITP diagnosis but also for ITP treatment monitoring

Measurement of charm and bottom production from semileptonic hadron decays in p + p collisions at √s = 200 GeV

Measurements of the differential production of electrons from open-heavy-flavor hadrons with charm- and bottom-quark content in p+p collisions at √s=200  GeV are presented. The measurements proceed through displaced-vertex analyses of electron tracks from the semileptonic decay of charm and bottom hadrons using the PHENIX silicon-vertex detector. The relative contribution of electrons from bottom decays to inclusive heavy-flavor-electron production is found to be consistent with fixed-order-plus-next-to-leading-log perturbative-QCD calculations within experimental and theoretical uncertainties. These new measurements in p+p collisions provide a precision baseline for comparable forthcoming measurements in A+A collisions.This article is published as Aidala, C., Y. Akiba, M. Alfred, V. Andrieux, N. Apadula, H. Asano, B. Azmoun et al. "Measurement of charm and bottom production from semileptonic hadron decays in p+ p collisions at s= 200 GeV." Physical Review D 99, no. 9 (2019): 092003. DOI: 10.1103/PhysRevD.99.092003. Posted with permission.</p