7 research outputs found

    Construction of Trust Relationship between Doctors and Patients: A Social Psychological Analysis

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    Doctor-patient trust is the basis of harmonious doctor-patient relationship. Social psychology plays a unique role in interpreting the connotation and construction of doctor-patient trust relationship. From the two levels of doctor-patient interpersonal trust and intergroup trust, this paper summarizes the relevant theoretical viewpoints of social psychology on the construction of doctor-patient trust relationship, and analyzes the key factors affecting doctor-patient interpersonal trust and intergroup trust. On this basis, this paper puts forward the construction path of doctor-patient trust of “interpersonal interaction-emotional communication-interpersonal trust” and “intergroup interaction-social knowledge-intergroup trust”, reveals the interaction mechanism of interpersonal trust and intergroup trust and the circular feedback mechanism between them to promote the formation of doctor-patient trust relationship, and establishes a social psychology model of the formation mechanism of doctor-patient trust relationship

    Regulation of jasmonate signaling by reversible acetylation of TOPLESS in Arabidopsis

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    The plant hormone jasmonate regulates plant immunity and adaptive growth through orchestrating a genome-wide transcriptional program. Key regulators of jasmonate-responsive gene expression include the master transcription factor MYC2, which are repressed by the conserved Groucho/Tup1-like co-repressor TOPLESS (TPL) in the resting state. However, the mechanisms underlying TPL-mediated transcriptional repression of MYC2 activity and hormone-dependent switching between repression and de-repression remain enigmatic. Here, we report the regulation of TPL activity through reversible TPL acetylation. The histone acetyltransferase GCN5 mediates TPL acetylation, which enhances its interaction with the NOVEL-INTERACTOR-OF-JAZ (NINJA) adaptor and promotes its recruitment to MYC2 target promoters, facilitating repression. Conversely, TPL deacetylation by the histone deacetylase HDA6 weakens TPL–NINJA interaction and inhibits TPL recruitment to MYC2 target promoters, facilitating activation. In a resting state, the opposing activities of GCN5 and HDA6 maintain TPL acetylation homeostasis, promoting TPL repression activity. In response to jasmonate elicitation, HAD6 expression is transiently induced, decreasing TPL acetylation and repressor activity, facilitating target gene activation. Thus, the GCN5–TPL–HDA6 module maintains the homeostasis of acetylated TPL, thereby determining the transcriptional state of jasmonate-responsive genes. Our findings uncovered a mechanism by which the TPL co-repressor activity in jasmonate signaling being actively tuned in a rapid and reversible manner

    Preparation and Magnetic Properties of Polycrystalline Eu 2 O 3 Microwires

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    In this paper, large-scale Eu 2 O 3 microwires with great length were successfully fabricated by a simple and facile electrodeposition and a subsequent heat-treatment. The morphology and structure of the as-deposited and the annealing microwires were studied in detail by SEM, EDS, XPS and TEM, and the results indicate that the as-deposited Eu(OH) 3 microwires are amorphous, and Eu 2 O 3 microwires after annealing are polycrystalline with body center cubic structure. Moreover, the magnetic properties of Eu 2 O 3 microwires were also investigated. The Eu 2 O 3 sample shows a non-typical magnetism which might result from oxygen vacancies confirmed by XPS
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