The effect of 2 different distraction-compression models on new bone generation

To compare the stimulating effect of distraction and 2 different distraction-compression models on maturation of new bone during healing. Thirty adult Sprague-Dawley rats underwent unilateral mandibular osteotomy. The animals were divided into 3 groups. A unidirectional external distraction device was fixed to the mandible. A total of 4 mm of distraction was planned in all groups. After a latency period of 3 days, 0.2 mm of distraction was performed twice a day for 10 days in the distraction group. In the intermittent distraction-compression group, 0.2 mm of distraction was performed twice a day for 3 days, followed by 0.2 mm of compression twice a day for 1 day. In the overdistraction-compression group, 0.2 mm of distraction was performed twice a day for 14 days, followed by 0.2 mm of compression twice a day for 4 days. After a consolidation period of 6 weeks in all groups, animals were killed for macroscopic, microscopic, and radiologic evaluation. Radiologic evaluation proved that more mature bone generation occurred in the groups in which compression was added to distraction. The number of osteoblasts in the intermittent distraction-compression group was significantly higher than that in the distraction group and overdistraction-compression group (P < .001). The highest number of vessels was found in the intermittent distraction-compression group (17.7 ± 6.4) (P < .001). The intermittent distraction- compression model was found to generate greater new bone compared with distraction alone. In clinical applications, to increase the quality of the bone and to shorten the consolidation period, compression can be applied during distraction. © 2012 American Association of Oral and Maxillofacial Surgeons

Clinical Features and Prognosis in Childhood Pneumococcal Meningitis

In this study, 50 children with pneumococcal meningitis were evaluated for the clinical manifestations and prognosis. The mean age was 44.9 months and 32% of the cases were 6 months old or younger. The most frequent physical findings were alteration in the level of consciousness (66%), fever (52%) and neck stiffness (in 50% of all the cases, and in 73.9% of the cases older than 2 years). Convulsions occured in 54% of the cases at home and/or at the hospital. Various neurologic sequelae were detected in 9 cases at discharge. Persistent hearing loss was detected in 28% of 25 cases who were evaluated. Six cases (12%) died. Cerebrospinal fluid (CSF) protein level > 200 mg/dL was a significant risk factor for mortality (p= 0.025). Besides, blood glucose level was significantly lower (p= 0.010) and CSF protein level was higher (p= 0.013) in the cases who died comparedto the cases who lived

Aging Slows Access to Temporal Information From Working Memory

To evaluate the impact of aging on controlled memory search operations, we investigated the retrieval of temporal order information from working memory (WM)

Assessment of Tissue Perfusion Following Conventional Liposuction of Perforator-Based Abdominal Flaps

Background The effect of liposuction on the perforators of the lower abdominal wall has been investigated in several studies. There are controversial results in the literature that have primarily demonstrated the number and patency of the perforators. The aim of this study was to determine the effect of liposuction on the perfusion of perforator-based abdominal flaps using a combined laser-Doppler spectrophotometer (O2C, Oxygen to See, LEA Medizintechnik). Methods Nine female patients undergoing classical abdominoplasty were included in the study. Perforators and the perfusion zones of the deep inferior epigastric artery flap were marked on the patient's abdominal wall. Flap perfusion was quantitatively assessed by measuring blood flow, velocity, capillary oxygen saturation, and relative amount of hemoglobin for each zone preoperatively, after tumescent solution infiltration, following elevation of the flap on a single perforator, and after deep and superficial liposuction, respectively. Results The measurements taken after elevation of the flap were not significantly different than measurements taken after the liposuction procedures. Conclusions The liposuction procedure does not significantly alter the perfusion of perforator-based abdominal flaps in the early period. The abdominal tissue discarded in a classic abdominoplasty operation can be raised as a perforator flap and has been demonstrated to be a unique model for clinical research

Hatay'da ipekçilik

Ankara : İhsan Doğramacı Bilkent Üniversitesi İktisadi, İdari ve Sosyal Bilimler Fakültesi, Tarih Bölümü, 2018.This work is a student project of the Department of History, Faculty of Economics, Administrative and Social Sciences, İhsan Doğramacı Bilkent University.The History of Turkey course (HIST200) is a requirement for all Bilkent undergraduates. It is designed to encourage students to work in groups on projects concerning any topic of their choice that relates to the history of Turkey. It is designed as an interactive course with an emphasis on research and the objective of investigating events, chronologically short historical periods, as well as historic representations. Students from all departments prepare and present final projects for examination by a committee, with 10 projects chosen to receive awards.Includes bibliographical references (pages 15-16).by İbrahim Mert Öztürk

Physical limitations on fundamental efficiency of set-based brownian circuits

Brownian circuits are based on a novel computing approach that exploits quantum fluctuations to increase the efficiency of information processing in nanoelectronic paradigms. This emerging architecture is based on Brownian cellular automata, where signals propagate randomly, driven by local transition rules, and can be made to be computationally universal. The design aims to efficiently and reliably perform primitive logic operations in the presence of noise and fluctuations; therefore, a Single Electron Transistor (SET) device is proposed to be the most appropriate technologybase to realize these circuits, as it supports the representation of signals that are token-based and subject to fluctuations due to the underlying tunneling mechanism of electric charge. In this paper, we study the physical limitations on the energy efficiency of the Single-Electron Transistor (SET)-based Brownian circuit elements proposed by Peper et al. using SIMON 2.0 simulations. We also present a novel two-bit sort circuit designed using Brownian circuit primitives, and illustrate how circuit parameters and temperature affect the fundamental energy-efficiency limitations of SET-based realizations. The fundamental lower bounds are obtained using a physical-information-theoretic approach under idealized conditions and are compared against SIMON 2.0 simulations. Our results illustrate the advantages of Brownian circuits and the physical limitations imposed on their SET-realizations.Electrical Engineering Educatio

Superficial Musculoaponeurotic System Flap for Reconstruction of the Intraoral Defects

Intraoral tumors are the main causes of the intraoral and maxillofacial defects. Skin grafts and several soft tissue flaps can be used to reconstruct the intraoral defects including local, regional, and free flaps. Here we present a case of intraoral adenocystic carcinoma treated with segmental maxillectomy, resection of the parotid gland, and the buccal mucosa leaving a full-thickness intraoral defect. The defect was covered with a superficial musculoaponeurotic system (SMAS) flap elevated using the preauricular incision. Reconstruction with SMAS flap for temporal defects and parotidectomy defects has been described in the literature. To our knowledge, the use of this flap for intraoral defects has not been reported. The proximity of the flap to the defect and ease of harvest in cases including total parotidectomy are few of the reasons we use and recommend this flap in reconstruction of intraoral defects

The effect of low dose teicoplanin-loaded acrylic bone cement on biocompatibility of bone cement

Antibiotic-loaded acrylic bone cement (polymethylmethacrylate, PMMA) is used to prevent or treat infection in total joint replacement surgery. The purpose of this study was to investigate biocompatibility and cytotoxicity of the teicoplanin-loaded acrylic bone cement. Cytotoxicity examination of acrylic bone cement balls and 400 mg teicoplanin added acrylic bone cement balls conducted by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide) assay. SEM (Scanning electron microscopy) was used to observe adhesion and spreading of cells on surface of the balls. Cytotoxicity examination conducted by MTT assay on acrylic bone cement balls and teicoplanin-added acrylic bone cement balls revealed no cytotoxicity. SEM analysis put forward that cells started to proliferate and adhere on surface of the samples in both groups as a result of 48-hour incubation and that the cell proliferation over acrylic bone cement and teicoplanin-added acrylic bone cement was similar. As a consequence, there was no cytotoxicity in acrylic bone cement and teicoplanin-added acrylic bone cement groups according to results of MTT assay. On the other hand, results of SEM showed that biocompatibility of both groups was similar. In conclusion, teicoplanin-loaded bone cement did not change biocompatibility of bone cement in studied dose