ANATOMICAL RELATIONSHIP OF FACIAL NERVE WITH EXTRATEMPORAL MARKERS AND SURGICAL SIGNIFICANCE

Purpose: Localization of the facial nerve trunk may be required during various surgical interventions such as parotidectomy. In these surgical applications, various and reliable landmarks are used to determine the localization of the facial nerve trunk. This anatomical cadaver study aims to evaluate the anatomical relationship between the facial nerve trunk, tragal pointer and mastoid tip

Anatomical relationships of the transmuscular portal to its surrounding structures in arthroscopic treatment of superior labrum anterior posterior lesions: A cadaveric study and preliminary report

Objective: This study aims to investigate the anatomical relationships of the transmuscular portal to its surrounding structures in arthroscopic treatment of superior labrum anterior posterior (SLAP) lesions in a human cadaveric model

In vitro Evaluation of Doxorubicin-Incorporated Magnetic Albumin Nanospheres

WOS: 000337665900011PubMed ID: 24524300Magnetic albumin nanospheres that incorporate doxorubicin (M-DOX-BSA-NPs) were prepared previously by our research group to develop magnetically responsive drug carrier system. This nanocarrier was synthesized as a drug delivery system for targeted chemotherapy. In this work, cytotoxic effects of doxorubicin (DOX)-loaded/unloaded or magnetic/non-magnetic nanoparticles and free DOX against PC-3 cells and A549 cells were determined with the MTT test and the results were compared with each other. DOX-loaded magnetic albumin nanospheres (M-DOX-BSA-NPs) were found more cytotoxic than other formulations. The quantitative data obtained from flow cytometry analysis further verified the higher targeting and killing ability of M-DOX-BSA-NPs than free DOX on both of the cancer cell lines. Additionally, the results of cell cycle analysis have showed that M-DOX-BSA-NPs affected G1 and G2 phases. Finally, cell images were obtained using spin-disk confocal microscopy, and cellular uptake of M-DOX-BSA-NPs was visualized. The findings of this study suggest that M-DOX-BSA-NPs represent a potential doxorubicin delivery system for targeted drug transport into prostate and lung cancer cells

VERMIAN FOSSA - AN ANATOMICAL STUDY

Objective: Vermian fossa (VF) is a shallow fossa of varying size which may occasionally be found on dorsal aspect of foramen magnum. Our aim was to find out frequency of VF and to measure length and width of the determined VF's and to classify them according to their shapes

Anatomy of the Dorsal Nerve of the Penis, Clinical Implications

OBJECTIVE To show the branching patterns and the anatomic variations of the dorsal nerve of the penis (DNP) along the penile shaft, particularly the relation with the tunica albuginea

An anatomic study of the lateral patellofemoral ligament

Objective: The lateral patellofemoral ligament (LPFL) is part of the lateral retinaculum cut during arthroscopic or open release. We investigated its anatomic and morphometric characteristics. Materials and methods: We identified the LPFL insertion point on the condyle in vertical and sagittal planes in 32 adult cadaveric knees. We measured its length and width at the insertion point. We located the midpoint of this point and measured from it to the distal and posterior condylar ends. We measured anterior-posterior and proximal-distal lateral condylar lengths. We evaluated the insertion point shape on the lateral femoral condyle. Degree of relationship between variables was assessed using Pearson's correlation coefficient. p < 0.05 was considered statistically significant. Results: The LPFL mean length was 23.2 mm, and mean width at the insertion point was 15.6 mm. Regarding its insertion into the lateral condyle, central insertions were more frequent (vertical plane: 53.1% central and sagittal plane: 75% central). A significant positive correlation was evident between the LPFL length and width at the insertion point (p = 0.05). Thus, the LPFL length was proportional to its width at the insertion point. A significant positive correlation was found between the anterior-posterior condylar length and width of the LPFL at the insertion point (p = 0.017). Therefore, greater anterior-posterior condylar length equates to a larger area of insertion on the condyle. Conclusion: Greater width of the LPFL at the insertion point corresponds to greater LPFL and anterior-posterior lateral condylar lengths. Keywords: Anatomic study, Lateral patellofemoral ligament, Lateral condyle of the femu