Estimating age-status-specific demographic rates that are consistent with the projected summary measures in family households projection

This paper proposes procedures for estimating age-status-specific demographic rates to ensure that the projected summary measures of marriage/union formation and dissolution and marital and non-marital fertility in the future years are achieved consistently. The procedures proposed in this paper can be applied in both macro and micro models for family household or actuarial/welfare projections and simulations that need the time-varying age-status-specific demographic rates as input.family demography

Estimating time-varying sex-age-specific o/e rates of marital status transitions in family household projection or simulation

This article presents a procedure for estimating time-varying sex-age-specific occurrence/exposure (o/e) rates of marital status transitions to ensure that the projected life course propensities of marriage/union formation and dissolution are achieved consistently in the one-sex family status life table model. Procedures for estimating time-varying sex-age-specific marital status transition o/e rates that are consistent with the two-sex constraints and projected summary measures of marriage/union formation and dissolution in the future years in the two-sex family household projection model is proposed. The procedures proposed in this article are practically useful and can be applied in both macro and micro models for family household projections or simulations that need time-varying sex-age-specific o/e rates of marital status transitions.family, household, marriage, projections, simulation

Estimating time-varying sex-age-specific o/e rates of marital status transitions in family household projection or simulation

This article presents a procedure for estimating time-varying sex-age-specific occurrence/exposure (o/e) rates of marital status transitions to ensure that the projected life course propensities of marriage/union formation and dissolution are achieved consistently in the one-sex family status life table model. Procedures for estimating time-varying sex-age-specific marital status transition o/e rates that are consistent with the two-sex constraints and projected summary measures of marriage/union formation and dissolution in the future years in the two-sex family household projection model is proposed. The procedures proposed in this article are practically useful and can be applied in both macro and micro models for family household projections or simulations that need time-varying sex-age-specific o/e rates of marital status transitions.

The yeast expression system for recombinant glycosyltransferases

Glycosyltransferases are increasingly being used for in vitro synthesis of oligosaccharides. Since these enzymes are difficult to purify from natural sources, expression systems for soluble forms of the recombinant enzymes have been developed. This review focuses on the current state of development of yeast expression systems. Two yeast species have mainly been used, i.e. Saccharomyces cerevisiae and Pichia pastoris. Safety and ease of fermentation are well recognized for S. cerevisiae as a biotechnological expression system; however, even soluble forms of recombinant glycosyltransferases are not secreted. In some cases, hyperglycosylation may occur, P. pastoris, by contrast, secrete soluble orthoglycosylated forms to the supernatant where they can be recovered in a highly purified form. The review also covers some basic features of yeast fermentation and describes in some detail those glycosyltransferases that have successfully been expressed in yeasts. These include β1,4galactosyltransferase, α2,6sialyltransferase, α2,3sialyltransferase, α1,3fucosyltransferase III and VI and α1,2mannosyltransferase. Current efforts in introducing glycosylation systems of higher eukaryotes into yeasts are briefly addresse

Field induced density wave in the heavy fermion compound CeRhIn5

Metals containing Ce often show strong electron correlations due to the proximity of the 4f state to the Fermi energy, leading to strong coupling with the conduction electrons. This coupling typically induces a variety of competing ground states, including heavy-fermion metals, magnetism and unconventional superconductivity. The d-wave superconductivity in CeTMIn5 (TM=Co, Rh, Ir) has attracted significant interest due to its qualitative similarity to the cuprate high-Tc superconductors. Here, we show evidence for a field induced phase-transition to a state akin to a density-wave (DW) in the heavy fermion CeRhIn5, existing in proximity to its unconventional superconductivity. The DW state is signaled by a hysteretic anomaly in the in-plane resistivity accompanied by the appearance of non-linear electrical transport at high magnetic fields (>27T), which are the distinctive characteristics of density-wave states. The unusually large hysteresis enables us to directly investigate the Fermi surface of a supercooled electronic system and to clearly associate a Fermi surface reconstruction with the transition. Key to our observation is the fabrication of single crystal microstructures, which are found to be highly sensitive to "subtle" phase transitions involving only small portions of the Fermi surface. Such subtle order might be a common feature among correlated electron systems, and its clear observation adds a new perspective on the similarly subtle CDW state in the cuprates.Comment: Accepted in Nature Communication

Intertwined Orders in Heavy-Fermion Superconductor CeCoIn5_5

The appearance of spin-density-wave (SDW) magnetic order in the low-temperature and high-field corner of the superconducting phase diagram of CeCoIn$_5$ is unique among unconventional superconductors. The nature of this magnetic $Q$ phase is a matter of current debate. Here, we present the thermal conductivity of CeCoIn$_5$ in a rotating magnetic field, which reveals the presence of an additional order inside the $Q$ phase that is intimately intertwined with the superconducting $d$-wave and SDW orders. A discontinuous change of the thermal conductivity within the $Q$ phase, when the magnetic field is rotated about antinodes of the superconducting $d$-wave order parameter, demands that the additional order must change abruptly together with the recently observed switching of the SDW. A combination of interactions, where spin-orbit coupling orients the SDW, which then selects the secondary $p$-wave pair-density-wave component (with an average amplitude of 20\% of the primary $d$-wave order parameter), accounts for the observed behavior

Wastewater Testing Shows that Pharmaceutical and Illicit Drug Use are Higher in Places where COVID-19 is More Prevalent

Wastewater testing shows that pharmaceutical and illicit drug use are higher in places were COVID-19 is more prevalent