Evaluation des sequelles chez les victimes d’accidents de la circulation

La loi n°2005-86 du 15 août 2005 a défini les préjudices indemnisables suite à un accident de la circulation: les frais de soins imputables à l’accident, la perte de revenus durant la période d’incapacité temporaire de travail, l’incapacité permanente partielle, le préjudice moral et esthétique, les frais d’assistance d’une tierce personne, le préjudice économique, le préjudice moral et les frais funéraires en cas de décès. Nous proposons une méthodologie d’évaluation de ces différents chefs de préjudice notamment les incapacités en otorhino- laryngologie.Mots clés : Expertise, Dommage corporel.The law n°2005-86 of 15 August 2005, defined prejudices to indemnify after a road accident: care expenses due to the accident, loss of incomes during the period of temporary inability of work, partial permanent inability, moral and aesthetic prejudice, expenses of assistance by a third person, economic prejudice, moral prejudice and funeral expenses in case of death. We propose a methodology of assessment of these different chiefs of prejudice, notably in otorhinolaryngology inabilities.  Key words: Expertise, Bodily damage

Suicide Among Adolescents in Center Tunisia: An 18-Year Autopsy Study

Background: Suicide and suicide attempts are more common among adolescents. Many factors are known to influence suicide in particular: region and culture. Adolescent suicide has been widely studied in many countries, but there are, currently, no data relating to adolescent suicide in Tunisia. Aim: The aims of this study were to describe epidemiological aspects of death related to adolescent suicide in Sousse, a city in central Tunisia. Methods: Data of forensic autopsies from 1998 to 2015 related to suicide of adolescents were retrospectively examined considering age, gender, method of death, year and risk factor. Results: 70 cases were reported with female predominance (62, 8%). The age range was from 10 to 19 and most of the suicides occurred in the 15-to-19 age group (75, 7%). Most victims were from rural zones (70%). Self-poisoning was the most used method (47, 1 %) followed by hanging (35, 7%). Hanging was the most common method used by males (17/26) and self-poisoning by females (29/44). Self-poisoning was related to pesticides in the vast majority of cases (29 cases among 33). The identified precipitating factors were chronic family problems in 51.4%, sentimental deception in 8.6%. Conclusion: This retrospective study raises concerns regarding the use of pesticides and the urgent need to provide rural areas with structures and medical equipment. This will ensure adequate suicide prevention in the region

De Novo Balanced Translocation t (7;16) (p22.1; p11.2) Associated with Autistic Disorder

The high incidence of de novo chromosomal aberrations in a population of persons with autism suggests a causal relationship between certain chromosomal aberrations and the occurrence of isolated idiopathic autism. We report on the clinical and cytogenetic findings in a male patient with autism, no physical abnormalities and a de novo balanced (7;16)(p22.1;p16.2) translocation. G-banded chromosomes and fluorescent in situ hybridization (FISH) were used to examine the patient's karyotype as well as his parents'. FISH with specific RP11-BAC clones mapping near 7p22.1 and 16p11.2 was used to refine the location of the breakpoints. This is, in the best of our knowledge, the first report of an individual with autism and this specific chromosomal aberration

Functional Identification of Neuroprotective Molecules

The central nervous system has the capacity to activate profound neuroprotection following sub-lethal stress in a process termed preconditioning. To gain insight into this potent survival response we developed a functional cloning strategy that identified 31 putative neuroprotective genes of which 28 were confirmed to provide protection against oxygen-glucose deprivation (OGD) or excitotoxic exposure to N-methyl-D-aspartate (NMDA) in primary rat cortical neurons. These results reveal that the brain possesses a wide and diverse repertoire of neuroprotective genes. Further characterization of these and other protective signals could provide new treatment opportunities for neurological injury from ischemia or neurodegenerative disease

Youth as Actors of Change? The Cases of Morocco and Tunisia

In the last decades, ‘youth’ has increasingly become a fashionable category in academic and development literature and a key development (or security) priority. However, beyond its biological attributes, youth is a socially constructed category and also one that tends to be featured in times of drastic social change. As the history of the category shows in both Morocco and Tunisia, youth can represent the wished-for model of future citizenry and a symbol of renovation, or its ‘not-yet-adult’ status which still requires guidance and protection can be used as a justification for increased social control and repression of broader social mobilisation. Furthermore, when used as a homogeneous and undifferentiated category, the reference to youth can divert attention away from other social divides such as class in highly unequal societies

Congruence of tissue expression profiles from Gene Expression Atlas, SAGEmap and TissueInfo databases

BACKGROUND: Extracting biological knowledge from large amounts of gene expression information deposited in public databases is a major challenge of the postgenomic era. Additional insights may be derived by data integration and cross-platform comparisons of expression profiles. However, database meta-analysis is complicated by differences in experimental technologies, data post-processing, database formats, and inconsistent gene and sample annotation. RESULTS: We have analysed expression profiles from three public databases: Gene Expression Atlas, SAGEmap and TissueInfo. These are repositories of oligonucleotide microarray, Serial Analysis of Gene Expression and Expressed Sequence Tag human gene expression data respectively. We devised a method, Preferential Expression Measure, to identify genes that are significantly over- or under-expressed in any given tissue. We examined intra- and inter-database consistency of Preferential Expression Measures. There was good correlation between replicate experiments of oligonucleotide microarray data, but there was less coherence in expression profiles as measured by Serial Analysis of Gene Expression and Expressed Sequence Tag counts. We investigated inter-database correlations for six tissue categories, for which data were present in the three databases. Significant positive correlations were found for brain, prostate and vascular endothelium but not for ovary, kidney, and pancreas. CONCLUSION: We show that data from Gene Expression Atlas, SAGEmap and TissueInfo can be integrated using the UniGene gene index, and that expression profiles correlate relatively well when large numbers of tags are available or when tissue cellular composition is simple. Finally, in the case of brain, we demonstrate that when PEM values show good correlation, predictions of tissue-specific expression based on integrated data are very accurate

Magnetocaloric properties in Ln(0.67)Ba(0.33)Mn(1-x)Fe(x)O(3) (Ln = La or Pr) manganites

International audienceWe have investigated the magnetocaloric properties of Ln(0.67)Ba(0.33)Mn(1-x)Fe(x)O(3) (Ln = La or Pr) manganites with x=0 and 0.05. All compounds present a maximum and large magnetocaloric effect near the Curie temperature (T-C). The associated maximum value of the magnetic entropy change, at 5 T applied change in the magnetic field, is 4.37 J.kg(-1).K-1 for Pr0.67Ba0.33MnO3 manganite with a T-C value of 205 K. The corresponding relative cooling power (RCP) reaches 230 J.kg(-1). All the samples present similar RCP values that are relatively high and are promising materials to be used in ecologically friendly magnetic refrigeration technology. Iron doping reduces both T-C and Delta S-M(max) and spreads the temperature working range with an almost constant RCP and can then be used to tune the working conditions of a refrigerator device. (C) 2011 Elsevier B.V. All rights reserved

Critical Behavior of La0.67Ba0.33Mn0.95Fe0.05O3 Manganite

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Above room temperature magnetocaloric effect in perovskite Pr0.6Sr0.4MnO3

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