All-optical sub-Kelvin sympathetic cooling of a levitated microsphere in vacuum

Funding: UK Engineering and Physical Sciences Research Council (EP/P030017/1).We demonstrate all-optical sympathetic cooling of a laser-trapped microsphere to sub-Kelvin temperatures, mediated by optical binding to a feedback-cooled adjacent particle. Our study opens prospects for multi-particle quantum entanglement and sensing in levitated optomechanics.Publisher PDFPeer reviewe

Predictors of coronary intervention-related myocardial infarction in stable angina patients pre-treated with statins

A b s t r a c t I In nt tr ro od du uc ct ti io on n: : Peri-procedural myocardial infarction (PMI) is a frequent and prognostically important complication of percutaneous coronary intervention (PCI). This study was designed to determine the predictors of PMI in patients pre-treated with statins. M Ma at te er ri ia al l a an nd d m me et th ho od ds s: : A total of 418 stable angina pectoris patients taking statins and aspirin were included. All the patients underwent PCI. Serum concentrations of creatine kinase (CK-MB mass) and troponin I (TnI) were measured prior to and then within 16 to 24 hours after PCI. The incidence of PMI was assessed using the established criteria (≥ 3 times upper limit of normal). R Re es su ul lt ts s: : Four hundred and eighteen stable patients (63 ±10 years, 68% males) were treated by PCI. The technical success rate of PCI was 99%. The incidence of PMI based on CK-MB mass or TnI release was 12% (PMI group). There were no significant differences in baseline clinical and procedural characteristics between PMI and non-PMI groups except for the balloon inflation time (40 ±44 s vs. 26 ±27 s; p = 0.02) and the proportion of treated type C lesions (42% vs. 28%; p = 0.03). In multivariate analysis, the independent predictors of PMI were balloon inflation time (OR = 1.01; 95% CI 1.001-1.020; p = 0.02) and preprocedural level of C-reactive protein (OR = 1.38; 95% CI 1.059-1.808; p = 0.02). C Co on nc cl lu us si io on ns s: : These results suggest that C-reactive protein and balloon ischaemic time are independent predictors of PMI in stable angina patients pre-treated with statins

Non-invasive diagnosis of involvement of the right ventricle in hypertrophic cardiomyopathy

Cll: Zjistil, 7.da u hypcrtrofícU hrdiomY0p"tic (HCM) je i v p!jpad~ nepl'lIomnosti hypertrofie prav~ komory (PK) pHtOnUlo po5lib::ni JYSlolicl:é a dia~toiicld f'unkee. lIodooeenl bylo prov:ldtno pomncl stntin, strnin nle a lkMlov!dopple-ovskéh07.obntzm; (lnI). Metodika a ~1edJ,:y: Ze 77 konsd&lt;utivuich pacientů J HCM po iuptiné .Ikoholo~ sepúlni ablaci jsem vyhnl sDlpi:nu 19 pacientu J HCM bet hypenrorlC PK. kterou jsem IJOVnai 5konlrolnlm """borem 22 jedind'l. PlII1iI1TIetry TOl byiy m~nmy na mitráLnlm a lrikuspid.ilnlm prstenci. Suain a strain ilite odvozený z TOl byl hodnocen v obLutj h1'Olovť= poloviny vol n ~ sltny I'K a v ba'lAlnlch scgmctl1ecb Icvt komory. Mezi o\Xnu slrnpinami byl n"lc;o:n s....tisticky výwamll~ rowil u T'K pouu pro izovolllmický precjckčni e..,.;, (79,2±17,3 nu VI 58,5±8.1 ms, p&lt;O,OI), i:rovolumický rd""ační čas ( I04,7±26,2 IIl5 VI 17,3±24,S mli, p&lt;O,OI), iDdex myobrdiilnl výkoonosti (rci) ~ený pomoci TI}I (0,6HO,14 VI 0,49±O,09, p&lt;O,OI) a velikost e..,.;,no! diastolické vlny T Ol (il,2±l,Scml,vs l2,9.i1,6cm1s; p&lt;O,OS). Záv~r: Tyto výsledky potvrzuji postiženi systolicld i diastolické funkce, PK II IICM i v neplitomnosti hypertrofie. Parametry ml SCl jevljako ",n:átivnějJ! ndslrain astraio ilite odvozcny:tTOLAim: The ~ulhor invesugatcd thc utility of !traio, ,trajo ratc, and tissue Doppler imagiDg (lDI) forthe evaluation oftbc right vcntticlc (RV) impainnenl io paritOU with a h)'P"nmphic c.rdiomyopathy (HCM) .flt;r ll. IUCOCSIIful alCQhoI ~ptal ablo.tÍOQ wilhout RV hypcrtrOphy in oomparion wilh C<XI.trolgroup. Mcthodl &lid RCSllII",: A group ol 19 plllÍCOl! sufl"erin, fmm IleM with 22 controls was compaml. The parametcra of TOl M:re evaluated in mitral IIOd lricuspid annulUI. SlrIIm lnd Anno BIC derivW from ml wcre I5Sessed in lUl apH.:al fret:waU ofRV, u wcLl KS in ""!lilI SCgolCflts ofthc len vcntriclc. lktwcen bulh groupS, !bere wcrc statlstically 8ignificant difTerencc~ only III ;,ovolumic pre- ejoction ume (79.2±11.3 ml vs 58.5±8.1 ros, JK{l.OI), iSDVOlulOk ,-e!ll)tllio!1 time (HI4.7±26.2 ms vs n .ll24.5 ms, p<O.OI), m~lalperfOl"TT\3l)(;e(Tci)tndex mcasurcd fmm TOl (O.6I±O.14 Vll 0.49J.0.09, ~.Ol). and early peak diastoli<: veloc:ity of TOl ( 11 .2±1.8cm1I1'112.'»2.6cmll;~.05). CooclUion: Tbc: rcsul" IiUg&amp;cJt the impainnent ofboth J)'$lOIi&lt;: and diastolic RV f,metlon in palients rutfering frum HCM. TOI-relaled paramctcrs appcar more Be\lBilivc than ,rmin and I traln Rte for evalUlltion.Department of CardiologyKardiologická klinika2. lékařská fakultaSecond Faculty of Medicin

Mullite Refractory Grog

Žárovzdorná ostřiva vyráběná z běžně dostupných jílů, jílovců a lupků v České republice většinou dosahují klasifikace šamotových ostřiv. Pro určité aplikace nejsou tato ostřiva vhodná a je potřeba použít ostřiva s vyšším obsahem oxidu hlinitého. Teoretická část diplomové práce je zaměřena na minerál mullit, který je jedním ze základních minerálů soustavy Al2O3 - SiO2. Rešerše je zaměřena na způsoby výroby mullitu, výrobu žárovzdorných ostřiv a nové možnosti modifikace stávajících surovin. V praktické části práce je provedeno ověření možnosti výroby ostřiv se zvýšeným obsahem Al2O3 podle navržených receptur.Refractory aggregate manufactured from common clays, claystones and shales in Czech Republic are mostly classified as fireclay. For specific applications are these grogs not suitable and there is a need to use grogs with higher content of alumina oxide. Theoretical part of this thesis is focused on the mineral mullite, which is one of the basic minerals in Al2O3 - SiO2 system. Research is focused on methods of mullite production, manufacture of recfractory grog and new possibilities in modification of current raw materials. In experimental part is carried out a verification of possible production of grogs with increased alumina content according to the designed composition.

Production of refractory aggregate in blast furnaces

Výpal žárovzdorných ostřiv probíhá v šachtových nebo rotačních pecích. Výchozí suroviny pro výpal jsou žárovzdorné jíly, jílovce a lupky. Před výpalem se provádí třídění a sítování suroviny, při kterém dochází ke vzniku jemných podílů jílů. Tento odpad je nepoužitelný pro výpal běžným způsobem v šachtových pecích. Možností, jak řešit tento problém, se jeví briketování jemných podílů. Vytvořením briket vhodného tvaru lze dosáhnout stejných vlastností jako u surového jílovce. Tento způsob zpracování jemných podílů s sebou dále přináší nové možnosti výroby žárovzdorných ostřiv. Přidáním vhodné korekční suroviny, jako například mullitického prášku, lze vyrábět speciální ostřiva s požadovanými parametry na přání zákazníka.Firing of refractory aggregate takes place in blast or rotary furnaces. Raw materials for firing are refractory clays, claystones and shales. Sorting and sieving is performed before firing, in which occurs to formation of the fine clay. This waste is not useful for firing in common way in blast furnaces. Possibility, how to solve this problem, seems to be briquetting of fine clays. This method of proccesing fine clays brings with it new possibilities in refractory aggregate production. By adding a suitable correction material, such as mullite powder, special refractory grog with required properties can be produced on customers wishes.

Development and Testing of Castables with Low Content of Calcium Oxide

Colloidal silica is used in many kinds of industry. It is an aqueous dispersion of SiO2 nanoparticles. SiO2 colloidal solutions are commercially available in different concentrations, with different particle sizes and are stabilized with different ions. Colloidal SiO2 was used in this study as a cement replacement in refractory castable. The present study, in its first stage, offers an assessment of five different SiO2 colloidal solutions. The particle size of the solutions was 15 nm, the particle concentration was 30% and 40% and the colloidal solutions were stabilized with Na+, OH&minus; and Cl&minus; ions. The effect of the colloidal solutions on selected characteristics of the refractory pastes and on their mineralogical composition after firing at 1000 &deg;C and 1500 &deg;C was described. The most suitable SiO2 colloidal solution from the first stage was subsequently used for the refractory castable test samples&rsquo; preparation in the second stage. Refractory castables, unlike paste, contain a coarse aggregate (grog) up to a grain size of 6 mm. Four types of coarse refractory grog were evaluated. Their effect on selected characteristics of the refractory castable and on its mineralogical composition after firing at 1000 &deg;C and 1500 &deg;C was described. The selected characteristics, within the scope of this study, include bulk density, apparent porosity, cold modulus of rupture and linear changes after firing. Finally, the study describes the effect of the sol particle concentration and the effect of pore size distribution on corrosion resistance and on the internal structure of the material. Mineral and chemical compositions and microstructures of both the raw materials and designed aggregates were thoroughly investigated by the means of X-ray fluorescence spectroscopy, powder X-ray diffraction and scanning electron microscopy. An analysis of the transition zone between corrosive media (K2CO3) and tested castables showed better corrosion resistance for a sol-gel castable than an ultra-low cement castable