Ambulatório de seguimento a pacientes oncológicos pós tratamento: sistematização e implantação da consulta de enfermagem ambulatorial

Trabalho apresentado no 31º SEURS - Seminário de Extensão Universitária da Região Sul, realizado em Florianópolis, SC, no período de 04 a 07 de agosto de 2013 - Universidade Federal de Santa Catarina.Trata-se de um projeto de extensão que busca sistematizar e implantar a consulta de enfermagem a pacientes pós-tratamento para câncer de mama, cólon e próstata atendidos no Ambulatório SUS do Hospital Santa Rita da Santa Casa de Misericórdia de Porto Alegre. As consultas de enfermagem iniciaram no dia 07 de junho de 2013, uma vez por semana, das 08:00 as 12:00 horas. A carga-horária prevista para o projeto é de 192 horas. Foram realizadas, até o momento, 7 consultas a pacientes com câncer de mama. A consulta compreende o histórico de enfermagem, identificação dos diagnósticos, as intervenções e os resultados esperados de acordo com a taxonomia NANDA I, Nursing Interventions Classification (NIC) e Nursing Outcomes Classification (NOC). Os registros são realizados em instrumentos desenvolvidos para este fim. Até o momento foram identificados 8 diagnósticos: Constipação (2); Eliminação intestinal prejudicada (1), Disfunção sexual (1), Risco de baixa autoestima(1), Risco de glicemia instável(1), Ansiedade(1), Dor crônica (2), Incontinência Urinária de Esforço (1), Nutrição desequilibrada: maior do que as necessidades corporais (1), Medo (1), Incontinência urinária de esforço (1), Risco de queda (1), Risco de trauma (1), Conhecimento deficiente (1), Risco para infecção (2). Dentre eles a constipação, dor crônica e risco de infecção foram mais evidenciadas. As intervenções de enfermagem foram realizadas no momento da consulta por meio de educação para a saúde, assim como o planejamento dos resultados que serão avaliados nas reconsultas. A ação busca contribuir para a promoção da saúde, a prevenção da doença, a manutenção da qualidade de vida, bem como no enfrentamento da situação de sobrevida e no preparo do paciente para o retorno de cuidado a saúde na atenção primária. No contexto do ensino, envolve a inserção do acadêmico de enfermagem no processo de trabalho para que possa desenvolver conhecimentos, habilidades e atitudes necessárias em sua formação profissional alinhada as necessidades de saúde desta população tanto no seguimento quanto na atenção primária

Prostasin, A Potential Tumor Marker in Ovarian Cancer- A Pilot Study

INTRODUCTION: Ovarian cancer is generally diagnosed at advanced stages of the disease; therefore, poor prognoses are typical. The development of tumor markers is thus of utmost importance. Prostasin is a protease that in normal tissues is highly expressed only in the prostate gland and seminal fluid. A previous study showed that prostasin is highly overexpressed in ovarian cancer cell lines. This study sought to evaluate the expression of prostasin in ovarian cancer. METHODS: Fresh tumor samples of ovarian epithelial cancer (n: 12) were analyzed for expression of prostasin mRNA (messenger ribonucleic acid) by conventional and real time quantitative PCR (polymerase chain reaction). As a standard control, a normal prostate sample was analyzed. RESULTS: Using conventional PCR, prostasin was detected in all but one sample. Using quantitative PCR, prostasin was over-expressed in all but one of the samples as compared to the control (prostate). CONCLUSIONS: These findings indicate that prostasin is overexpressed in many epithelial ovarian cancers. Further studies of prostasin as a potential biomarker for this disease are warranted

Laparoscopy versus laparotomy for FIGO stage 1 ovarian cancer (Review)

Background This is an updated version of the original review that was first published in the Cochrane Database of Systematic Reviews 2008, Issue 4. Laparoscopy has become an increasingly common approach to surgical staging of apparent early-stage ovarian tumours. This review was undertaken to assess the available evidence on the benefits and risks of laparoscopy compared with laparotomy for the management of International Federation of Gynaecology and Obstetrics (FIGO) stage I ovarian cancer. Objectives To evaluate the benefits and risks of laparoscopy compared with laparotomy for the surgical treatment of FIGO stage I ovarian cancer (stages Ia, Ib and Ic). Search methods For the original review, we searched the Cochrane Gynaecological Cancer Group Trials (CGCRG) Register, Cochrane Central Register of Controlled Trials (CENTRAL 2007, Issue 2), MEDLINE, EMBASE, LILACS, Biological Abstracts and CancerLit from 1 January 1990 to 30 November 2007. We also handsearched relevant journals, reference lists of identified studies and conference abstracts. For this updated review, we extended the CGCRG Specialised Register, CENTRAL, MEDLINE, EMBASE and LILACS searches to 6 December 2011. Selection criteria Randomised controlled trials (RCTs), quasi-RCTs and prospective cohort studies comparing laparoscopic staging with open surgery (laparotomy) in women with stage I ovarian cancer according to FIGO. Data collection and analysis There were no studies to include, therefore we tabulated data from non-randomised studies (NRS) for discussion. Main results We performed no meta-analyses. Authors’ conclusions This review has found no good-quality evidence to help quantify the risks and benefits of laparoscopy for the management of earlystage ovarian cancer as routine clinical practice

Laparoscopy versus laparotomy for FIGO stage 1 ovarian cancer (Review)

Background Over the past ten years laparoscopy has become an increasingly common approach for the surgical removal of early stage ovarian tumours. There remains uncertainty about the value of this intervention. This review has been undertaken to assess the available evidence of the benefits and harms of laparoscopic surgery for the management of early stage ovarian cancer compared to laparotomy. Objectives To evaluate the benefits and harms of laparoscopy in the surgical treatment of FIGO stage I ovarian cancer (stages Ia, Ib and Ic) when compared with laparotomy. Search methods Trials were identified by searching the Cochrane Gynaecological Cancer Group Trials Register, Cochrane Central Register of Controlled Trials (CENTRAL),TheCochrane Library Issue 2, 2007,MEDLINE (January 1990 toNovember 2007), EMBASE (1990 toNovember 2007), LILACS (1990 toNovember 2007), BIOLOGICALABSTRACTS (1990 toNovember 2007) andCancerlit (1990 toNovember 2007). We also searched our own publication archives, based on prospective handsearching of relevant journals from November 2007. Reference lists of identified studies, gynaecological cancer handbooks and conference abstract were also scanned. Selection criteria Studies including patients with histologically proven stage I ovarian cancer according to the International Federation of Gynaecology and Obstetrics (FIGO). Studies comparing laparoscopic surgery with laparotomy for early stage ovarian cancer were only available from1990. It was anticipated that a very small number of randomised controlled trials (RCTs) were conducted studying themanagement of early stage ovarian cancer. Therefore, non-randomised comparative studies, cohort studies and case-controls studies, but not studies with historical controls, were also considered. Data collection and analysis Data extraction was performed independently by five review authors (LRM, DDR, MIR, MCB and MIE) who assessed study quality and quality of extracted data. Extracted data included trial characteristics, characteristics of the study participants, interventions and outcomes. The quality of non RCTs was assessed using appropriate quality evaluations tools from the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) and from the Newcastle-Ottawa tool for observational studies (NOS). Main results No RCTs were identified. Three observational studies were identified. Authors’ conclusions This review has found no evidence to help quantify the value of laparoscopy for the management of early stage ovarian cancer as routine clinical practice

Associaçao da Videolaporoscopia e Quimioterapia Neoadjuvante no Tratamento do Carcinoma de Ovário. Uma Proposta Terapêutica: Relato de um Caso

O presente artigo constitui-se do relato de caso de uma paciente portadora de carcinoma de ovário estádio III (FIGO), que foi submetida à videolaparoscopia como primeira etapa do tratamento. Em virtude da dificuldade da realização de uma citorredução adequada, optou-se por quimioterapia neoadjuvante, seguida pela cirurgia citorredutora. Os autores apresentam os resultados obtidos, bem como a revisão bibliográfica sobre o assunto

Evidências para uma etiologia comum entre carcinomas de endométrio e tumores malignos mullerianos mistos

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