Entwicklung von zwei Langzeitmessverfahren der Tubenfunktion: Tensometrie und Optotensometrie

Eine Tubenfunktionsmessung ist bis heute nicht möglich. Zielstellung war die Entwicklung von Langzeitmessverfahren der Tubenfunktion, um die Trommelfellbewegungen, die durch Druckänderungen im Mittelohr entstehen, langzeitig messen zu können. Der erste Lösungsansatz war, Trommelfellbewegungen mit Dehnungsmessstreifen langzeitig messen zu können. Der zweite Lösungsansatz war die Entwicklung eines optischen Messsystems. Mit beiden Vefahren konnten wir Membranauslenkungen, die typisch sind für Druckausgleichsmanöver, messen. Dies war auch für simulierte pathologische Trommelfellbefunde möglich

Matrix change of bone grafting substitute after implantation into guinea pig bulla

Background: Many different surgical techniques have been developed to remove open mastoid cavities. In addition to autologous materials, alloplastic substances have been used. A very slow absorption of these materials and extrusion reactions have been reported. We investigated a newly developed, highly porous bone grafting material to eliminate open mastoid cavities, in an animal model. To characterise the transformation process, the early tissue reactions were studied in relation to the matrix transformation of the bone material. Material and methods: NanoBone (NB), a highly porous bone grafting material based on calcium phosphate and silica, was filled into the open bullae from 20 guinea pigs. The bullae were examined histologically. Energy dispersive X-ray spectroscopy (EDX) was used to investigate the change in the elemental composition at different sampling times. The surface topography of the sections was examined by electron microscopy. Results: After 1 week, periodic acid-Schiffs (PAS) staining demonstrated accumulation of glycogen and proteins, particularly in the border area of the NB particles. After 2 weeks, the particles were evenly coloured after PAS staining. EDX analysis showed a rapid absorption of the silica in the bone grafting material. Conclusions: NanoBone showed a rapid matrix change after implantation in the bullae of guinea pigs. The absorption of the silica matrix and replacement by PAS-positive substances like glycoproteins and mucopolysaccharides seems to play a decisive role in the degradation processes of NB. This is associated with the good osteoinductive properties of the material

The effect of stopping visiting hours during the COVID-19 pandemic on loneliness and mood in patients at an intermediate care hospital

BACKGROUND: To study how mood and feelings of loneliness in our in-patients differed before and after the re-introduction of social visits during COVID-19 restrictions.METHODS: The University of California, Los Angeles [UCLA] loneliness scale, the Hospital Anxiety and Depression Scale [HADS] and the Cornell scale were applied to all in-patients in an intermediate care hospital who fulfilled the inclusion criteria during two separate periods between May and September 2020, prior and after the re-introduction of limited visiting hours.RESULTS: 45 patients were included in the 1st phase and 30 patients during the 2nd phase. 66.7% were female and 33.3 % male. There was a significant difference in all the test results between the 1st and 2nd phase of the study (HADS-A p=0.0191; HADS-D p=0.0447; Cornell p=0.0037; UCLA p=0.0376).CONCLUSION: Social visits, even when limited in nature can still have a positive effect on patient’s mood and level of loneliness.peer-reviewe

Berolina

BEROLINA Berolina / Zehlicke, Adolf (Public Domain) ( - ) Title page ( - ) Handschriftliche Notiz ( - ) Caput I ( - ) Caput II (9) Caput III (13) Caput IV (17) Caput V (21) Caput VI (26) Caput VII (31) Caput VIII (35) Caput IX (38) Caput X (42) Caput XI (46) Caput XII (51) Caput XIII (56) Caput XIV (60) Caput XV (64) Caput XVI (69) Caput XVII (73) Caput XVIII (79) Caput XIX (83) Caput XX (86) ColorChart ( -

Berolina

BEROLINA Berolina / Zehlicke, Adolf (Public Domain) ( - ) Title page ( - ) Caput I ( - ) Caput II (9) Caput III (13) Caput IV (17) Caput V (21) Caput VI (26) Caput VII (31) Caput VIII (35) Caput IX (38) Caput X (42) Caput XI (46) Caput XII (51) Caput XIII (56) Caput XIV (60) Caput XV (64) Caput XVI (69) Caput XVII (73) Caput XVIII (79) Caput XIX (83) Caput XX (86) ColorChart ( -