An assessment of environmental-resources base for the development and well-being in Eritrea: a case study of Adi keih subzone

People in developing countries are most part agrarian and pastoral folk. They heavily rely on the bio-mass-based subsistence economies around them. The rural folk eke out a living from products obtained directly from plants and animals. This is particularly significant for marginal groups, who tend to rely more directly on their environment for survival. In this research paper researchers have tried to assess environmental resource base in Adi Keih subzone of Zoba Dobub (Eritrea) and their effects on the wellbeing and development of the people. Study is based on both primary and secondary sources of information. Study reveals that current available resource-base in the study region is impoverished. Only 10 per cent of the area has potentiality for the farming activities. Among them 80 per cent are poor quality agricultural lands. Farming activity supports only 1/3 of household income. In totality immediate environment supports merely average 50% of household income requirements. This problem has compounded due to environmental degradation. The study highlights micro level relationship between environmental degradation, and resulting in poverty

Chemical constituents of Desmodium sequax

1081-108

SCREENING OF SYNTHETIC NEW HETEROCYCLIC DERIVATIVES OF 3- FORMYL-4-HYDROXYCOUMARIN FOR ANTI-INFLAMMATORY ACTIVITY IN ALBINO RATS

Coumarins have multiple biological activities; various coumarin-related derivatives arerecognized as inhibitors of the lipoxygenase and cycloxygenase pathways of arachidonatemetabolism. Several natural or synthetic coumarins with various hydroxyl and other substituteswere found to inhibit lipid peroxidation and to scavenge hydroxyl radical and superoxide anionand to influence processes involving free radical mediated injury. The heterocyclic derivatives of3-formyl-4-hydoxycoumarin were found to present significant anti-inflammatory effect, thecompounds inhibited formalin induced hind paw edema and they also significantly suppressedthe formation of granuloma tissue in cotton pellet induced chronic model of inflammation. Theresult showed that the anti-inflammatory (both acute & chronic) effect of the test compound Ib iscomparable to that of standard Antiinflammatory drug Diclofenac Sodium

Novel pyrazolopyrones from enol lactones

1609-1613The one pot and facile condensation reaction of 5-chloro-3-methyl-1-phenylpyrazole-4-carboxaldehyde 1, 5-azido-3-methyl-1-phenylpyrazole-4-carboxaldehyde 2 with triacetic acid lactone 3 and 4-hydroxycoumarin 4 affords isomeric pyrazolopyrones viz. 4-(4-hydroxy-6-methyl-2-oxo-2H-pyran-2-one-3-yl)-3,7-dime­th­yl-1-phenylpyrazolo­[3,4:2,3]-4H-pyrano [3,2-b]pyran-5-one 6, 4-(4-hydroxy-6-methyl-2-oxo-2H-pyran-2-one-3-yl)-3,7-dimethyl -1-phenylpyrazolo[3,4:2,3]-4H-pyrano[3,2-c]pyran-5-one 7 and 4-(4-hydroxy-2-oxo-2H-1-benzopyran-2-one-3-yl)-3-methyl-1-phenyl­pyrazolo[3,4:2,3]-4H-pyrano[3,2-b]-1-benzopyran-5-one 8, 4-(4-hydroxy-2-oxo-2H-1-benzopyran-2-one-3-yl)-3-methyl-1-phenyl­pyrazolo[3,4:2,3]-4H-pyrano[3,2-c]-1-benzopyran-5-one 9 res­pecti­­vely. The condensation reaction which has led to the forma­tion of isomeric compounds is similar to Simonis conden­sa­tion reaction of oxoesters. The structures of all newly synthesized compounds have been determined by IR, 1H NMR and mass spectral data