120 research outputs found
Author's term: what is it? / defining the concept "author's term"
In the article the researchers state that in contemporary Russian terminology there is no concept “author's term” and no author’s term definition. Traditionally it has been accepted that the author's term is a term with a reliably known authorship, or a term named after the discoverer of a scientific phenomenon. The researchers consider this approach to be erroneous and suggest that the author's term exists only within the author’s original scientific hypothesis. As this hypothesis is described by the system of interrelated concepts and terms, so there is no isolated author’s term. The researchers offer their own definition of the author's term. The author’s term is a special sign created within the framework of a unique scientific theory, an element of the system of concepts interconnected with other terms and concepts of original hypothesis, referred by the speakers of the language for specific purposes to a specific author's idea, representing scientific picture of the world which is not generally accepted
The investigation of the time characteristic of local polar inhomogeneities in paraelectric phase in relaxors and ferroelectric crystals: on the example of SrxBa1-xNb2O6 crystals with different chemical composition
The reported study was funded by RFBR according to the research projects No. 18-02-00399 and State assignment No AAAAA17-117052410033-9. The experiments were performed in the multiple-access center “High-Resolution Spectroscopy of Gases and Condensed Matter” in IA&E SBRAS (Novosibirsk, Russia)
Changes of gas metabolism, gas homeostasis and tissue respiration in rats during prolonged hypokinesia
The oxygen uptake and tissue gas homeostasis of restrained albinic rats remained relatively constant during a 60 day experiment. The gas metabolism in some tissues changed, and O2 consumption increased in the liver and decreased in the myocardium. Capacity for physical work was reduced by five times. Hypokinesia for 60 days resulted in a delay in the animals growth
Manifestation of local polar regions in spectroscopic investigations in ferroelectrics and relaxors
The reported study was funded by RFBR according to the research project 18-02-00399 and State assignment No AAAA-A17-117052410033-9. Experiments were performed in the multiple-access center “High-Resolution Spectroscopy of Gases and Condensed Matter” in IA&E SBRAS (Novosibirsk, Russia)
Adaptability of high-protein barley genotypes under the conditions of the Volga-Vyatka region
Background. Barley grain is unique raw material of versatile uses. More than 60% of the grain produced In the Volga-Vyatka region goes directly to fodder production purposes. One of the urgent tasks is to develop high-yielding cultivars with good grain quality, thus reducing protein deficiency in farm animal feeds and meeting the need for fodder grain that increases every year. Its successful solution requires a search for new high-yielding and high-protein source genotypes adapted to the conditions of the Volga-Vyatka region and their involvement in the breeding process.Materials and methods. Experimental work was carried out in 2018–2020 at the Federal Agricultural Research Center of the North-East named N.V. Rudnitsky, Kirov. Protein content in grain, yield, resistance to lodging, and duration of the growing season of 31 barley accessions were assessed. The barley collection was studied according to the International COMECON List of Descriptors for the Genus Hordeum L. and Methodological Guidelines. Protein content was measured using a universal rapid analyzer (INFRAMATIC 8620).Results and conclusions. Protein content had a strong correlation with Selyaninov’s hydrothermal coefficient in the interphase period from ear emergence to maturity (r = 0.85); the sum of effective temperatures during the entire growing season (r = 0.75); and precipitation in the period from seedling emergence to maturity (r = 0.67). Traits of breeding value (yield, lodging resistance, environmental plasticity, and stability) were observed in the following accessions: k-30574 (‘Filippa’, Sweden), k-30256 (‘Rodos’, Poland), ya-52 (‘Crusades’, Great Britain), k-35415 (NCL 95098, Argentina), k-30892 (‘Naran’, Russia), k-15619 (‘Polyarny 14’, Russia), ya-4 (752A, Switzerland), k-30349 (Landrace, Peru), k-5983 (Local, Afghanistan), k-3506 (Local, India), k-2929 (Local, China), k-2930 (Local, China), and k-5210 (‘Makbo’, Australia)
Late Antiquity: The Regional Specific Nature of Intellectual Tradition
The primary purpose of the study is to investigate the specifics of the intellectual tradition prevailing in some regions of the Late Antique world. For the purpose of a comprehensive review of the problem, the authors focus on well-known intellectuals of the 5th–6th centuries, representing Gaul (Ausonius, Sidonius, Ennodius et al.), Alexandria (John Philoponus, Hypatia, Sinesius of Cyrene et al.), Africa (Fulgentius, Priscian, Corippus), Isauria (Candidus Isaurus). Despite the fact that, under the influence of objective factors (Christianization, barbarians), the intellectual tradition changed from its ancient model to the medieval one, it fulfilled its most important task - to preserve the best from the treasury of ancient thought and adapt the ancient heritage to a changing world. In conclusion, the outcomes of the study demonstrate various examples of intellectual tradition and the fortunes of “people of written culture” (literati)
CLINICAL AND INSTRUMENTAL CHARACTERISTICS OF JUVENILE CHRONIC ARTHRITIS EVOLUTION
The purpose of the study was to investigate the clinical symptoms and evolution of juvenile chronic arthritis (JCA) at different stages of it development. 39 children with duration of JCA from 6 months to 5 years in age from 2 to 18 years were examined. All patients underwent clinical examination, indicators of acute phase of inflammation (CRP, sialic acid, seromucoid, glycoproteins), rheumatoid factor, circulating immune complexes, complement, instrumental methods (X-ray and ultrasound, capillaroscopy of nail bed) were evaluated. Activity of the disease was estimated by disease activity score (DAS28). Statistically was determined the relative value (P). It was found that the disease started with monoarthritis (63,37 %). In the future, in half of the patients was formed oligoarthritis with damaging of large and medium-sized joints (68,25 %). In the majority of surveyed disease occurred against the backdrop of the minimal activity of the inflammatory process. On the stages of evolution recurrence of arthritis were observed in one third of children. If duration of the sickness is more than 5 years, it has become less frequent, than in previous years. The absence of clinical and radiographic manifestations of JCA after the abolition of medical treatment within one year, became the basis for the assumption that the disease remission, which was on the third year of the disease 25,93 %, on the fourth – 33,33 %, on the fifth – 36,36 %. The absence of radiographic signs of bone destruction, disability of patients allows interpreting JCA as a positive option of chronic juvenile idiopathic arthritis
POLARIMETRIC RESEARCH OF PHARMACEUTICAL SUBSTANCES IN AQUEOUS SOLUTIONS WITH DIFFERENT WATER ISOTOPOLOGUES RATIO
Objective: Methodology development for quality control of optically active pharmaceutical substances based on water isotopologues.
Methods: Solutions of L-ascorbic acid, glucose, galactose and valine stereoisomers were prepared using deuterium depleted water (DDW-«light» water, D/H=4 ppm), natural deionized high-ohmic water (BD, D/H=140 ppm), heavy water (99.9% D2O). The optical rotation was observed using an automatic polarimeter Atago POL-1/2. The size distribution of giant heterogeneous clusters (GHC) of water was recorded by low angle laser light scattering (LALLS) method.
Results: The infringement of Biot's Law was found for solutions of ascorbic acid, expressed in the absence of a constant value of the specific optical rotation  at a concentration of below 0.1%, depends on the D/H ratio. The inequality was established in absolute values of optical rotation for L-and D-isomers of valine in solutions with different ratios of hydrogen isotopologues. The mutarotation of glucose confirmed the first-order kinetics, and the activation energies were statistically distinguishable for BD and DDW. The mutarotation of the natural galactose D-isomer proceeded with a lower energy consumption compared to the L-isomer. In heavy water, the mutarotation of monosaccharides had different kinetic mechanisms. Polarimetric results correlated with the number and size of GHC, which confirmed the possibility of chiral solvent structures induction by optically active pharmaceutical substances.
Conclusion: In the optically active pharmaceutical substances quality control there should be considered the contribution of induced chiral GHC of water to the optical rotation value that depends on the isotopic D/H ratio, the substance nature and the form of its existence at a given pH
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