5 research outputs found
Fenugreek: A therapeutic complement for patients with borderline hyperlipidemia: A randomised, double-blind, placebo-controlled, clinical trial
Objective: Fenugreek (Trigonella foenum-graecum) is a medicinal plant from Fabaceae family. This clinical
study was designed to evaluate the effects of Fenugreek seeds supplementation on serum biochemical
parameters of patients with borderline hyperlipidemia.
Materials and methods: A randomised, double-blind, placebo-controlled clinical trial was conducted on 56
patients with borderline hyperlipidemia that were divided in two groups: F group received 8 g Fenugreek
seeds powder sachets and P group received placebo sachets daily for 8 weeks. After 2 months,
triglycerides (TG), total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL),
fasting blood glucose (FBG) and body mass index (BMI) were evaluated and compared with the baseline.
Results: After 2 months, TG, TC, LDL and FBG significantly decreased in F group in comparison with P
group, but these changes were not significant in HDL and BMI.
Conclusion: Our
findings showed that Fenugreek seeds supplementation, as a phenolic-rich herb can be
effective in the reduction of some lipid profile in patients with borderline hyperlipidemi
Predictors of the work-related depressive symptoms among blue-collar male employees of an industrial unit in Iran.
BACKGROUND AND AIM
Possible associations between depressive symptoms and work-related parameters have frequently been discussed in the literature. The present study was aimed to evaluate the work-related depressive symptoms and their possible-related parameters among male employees of Esfahan Steel Company (ESCO) as one of the most important industrial sites in Iran.
MATERIALS AND METHODS
With a cross-sectional design and a stratified random sampling method in 2010, a total of 400 male employees were enrolled from the operational parts of the ESCO.
RESULTS
Among 400 participated employees, 245 (61.3%) were rotational duty employees and 358 (89.5%) were reported making <$500. After applying the linear regression model, some variables including: economic difficulties (P = 0.022, odds ratio [OR] = 0.558, 95% confidence interval [CI] =0.339-0.919), family-related problems (P = 0.003, OR = 0.303, 95% CI = 0.138-0.669), and work environment (P < 0.001, OR = 0.244, 95% CI = 0.140-0.426) were found to be significantly associated with higher depressive symptoms among the participants.
CONCLUSION
The present study brought to light the predictors of occupational depressive symptoms among blue-collar employees of ESCO. More research is needed to find the causal relations between mental health and work-related parameters among Iranian employees
Effect of oral administration of Fenugreek seeds powdered on lipid profile
Effect of oral administration of Fenugreek seeds powdered on lipid profile
Background: Atherosclerosis is the major cause of death in the developed country. Impairment in plasma lipoproteins and the metabolism of fats related in the pathogenesis of atherosclerosis more than any other factors. Therefore control and treatment of hyperlipidemia, seems to be necessary. In recent years public tendency of societies to traditional medicine and the use of herbal medicines has been increasing. The role of various herbs in reducing blood lipids and reduce cardiovascular disease have been identified. In this context, can mentioned fenugreek, dill and walnut leaves. In Iran, human studies that indicate the effects of these herbs on blood lipids, has limited. Thus present study aimed to evaluate the effect of oral administration of powdered Fenugreek seed on the lipid profile.
Methods: This study was Clinical Trial and conducted on 49 hyperlipidemia patients who were not use lipid-lowering medications. Patients were randomly divided into treatment and control groups (24 treatment group and 25 control group) and both groups received nutritional education regarding diet changes and lifestyle. Also treatment group received 5 g/d of powdered of fenugreek seeds (as a package) for 8 weeks with food. Tchol, TG, LDL, HDL and FBS of patients were measured at the beginning and end of the study and finally data were compared using paired t test.
Result: the results indicate significant decrease (p<0.05) among treatment group in LDL, Tchol , TG and FBS . There was no significant change was seen in HDL of patient in neither of the two groups.
Conclusion: the results of this study showed that consumption of fenugreek seeds powdered is effective in reduce of blood lipids in hyperlipidemia patients.
Keywords: Fenugreek, Hyperlipidemia, lipid Profile