25 research outputs found
2-[4-Benzyl-5-(2-furyl)-4H-1,2,4-triazol-3-ylsulfanyl]acetamide
In the title compound, C15H14N4O2S, the phenyl ring is inclined at 70.25 (6)° with respect to the approximately planar furyl–triazolsulfanyl–acetamide unit. In the crystal structure, molecules related by inversion centers form dimers via intermolecular N—H⋯O hydrogen bonds between acetamide groups, resulting in eight-membered rings with an R
2
2(8) motif. In addition, the other H atom of the acetamide group is involved in an intermolecular hydrogen bond with an N atom of the triazole ring, resulting in chains extended along the c axis. The overall effect is the formation of a hydrogen-bonded two-dimensional framework perpendicular to the a axis
4-Ethyl-3-(3-pyridyl)-1H-1,2,4-triazole-5(4H)-thione 0.095-hydrate
The title compound, C9H10N4S·0.095H2O, consists of discrete 4-ethyl-3-(3-pyridyl)-1H-1,2,4-triazole-5(4H)-thione molecules and a disordered molecule of water of hydration with partial occupancy, lying on a twofold rotation axis. The dihedral angle between the pyridine and triazole rings is 41.73 (8)°. In the crystal structure, molecules are hydrogen bonded via triazole NH groups and pyridyl N atoms, forming chains parallel to the a axis
EXPLORING THE BARRIERS TO FEMALE-LITERACY FROM PARENTS AND TEACHERS’ PERSPECTIVE: A REVIEW STUDY OF SCATTERED LITERATURE
The article was a review study. This is an approach which allows the researcher to understand the phenomenon in depth (Karamustafaoglu, 2009). The researchers have adopted the literature review approach to investigate the problem in depth. The structures of literature have been analyzed through the handbooks mostly in the field of teacher education on literacy terms. This was a review study about exploring barriers to literacy from parents and teachers’ perspective. This was linked to the current literature in understanding about the phenomenon which was investigated. This study, therefore, relied on different kinds of literature such as published articles, theses and, books. Majority of them were obtained from research databases such as Web of Science and Google Scholar. Namamba and Rao (2017), and Manzar-Abbas and Lu (2013) followed the same method of review in conducting their review studies. In order to obtain relevant literature, search words such as “barriers to literacy” and “parents and teachers’ perspective” were used. In addition, books on teacher education were also consulted. All the obtained literature was summarized according to the search words of the study. All the obtained literature was cited properly in text and in the list. This allowed the researchers to extract and incorporate key information about exploring barriers to literacy from parents and teachers’ perspective into this article. The studies drawn in this review article reflect the learning about barriers to literacy from parents and teachers’ perspective in diverse directions. Article visualizations
N′-(2-Fluorobenzoyl)benzohydrazide
In the crystal structure of the title compound, C14H11FN2O2, the molecule is centrosymmetric. The F atom is disordered over four positions, on the two ortho positions of each ring, with occupancies of 0.287:0.213 (5). In the crystal structure, molecules are linked by intermolecular N—H⋯O and C—H⋯O hydrogen bonds
Carbonic anhydrase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozymes I and II with some 1,3,4-oxadiazole-thiols.
A series of chiral 1,3,4-oxadiazole-5-thiols incorporating 2-substituted-benzenesulfonamide moieties has been prepared from amino acids, via the ester and carbohydrazide intermediate, followed by cyclization with carbon disulfide. Some of these compounds have been investigated for the inhibition of three physiologically relevant carbonic anhydrase (CA, EC 4.2.1.1) isoforms, the human cytosolic hCA I and II, and the human, transmembrane, tumor-associated isozyme hCA IX. All these compounds showed weak (millimolar) affinity for the three isozymes, except two carbohydrazides and two heterocyclic thiols which selectively inhibited the tumor-associated isozyme with inhibition constants around 10 microM. Such compounds constitute interesting lead molecules for the possible design of CA IX-selective inhibitors
Synthesis and antimalarial activity of novel chiral and achiral benzenesulfonamides bearing 1, 3, 4-oxadiazole moieties.
A series of new benzenesulfonamides, most of which are chiral, incorporating 1, 3, 4-oxadiazole and amino acid moieties have been synthesized. Some of these compounds were screened for antimalarial activity and also evaluated for their ability to inhibit hem polymerization. The electrophoretic analysis indicated that one compound was effective in inhibiting the degradation of hemoglobin. The synthesized compounds were tested in mice infected with Plasmodium berghei. These derivatives have the potential for the development of novel antimalarial lead compounds
2-Chlorobenzohydrazide
The asymmetric unit of the the title compound, C7H7ClN2O, contains two molecules in which the chlorophenyl and the formic hydrazide units are almost planar (r.m.s. deviations of 0.0081 and 0.0100 Å, respectively, in one molecule and 0.0069 and 0.0150 Å in the other) and are oriented with respect to each other at dihedral angles of 56.8 (2) and 56.9 (2)°. In the crystal, the molecules are consolidated in the form of polymeric chains extending along [010]. R
3
3(10) ring motifs exist due to N—H⋯O and N—H⋯N hydrogen bonds
The Impact of COVID-19 on University Library Services: A Systematic Literature Review
The impact of COVID-19 on university library services is a less researched area. For the systematic literature review, the researchers searched Scopus, Web of Science, and Google Scholar. Initially, the researchers found 903 potentially relevant citations. From 903, 427 duplicate citations were removed. The remaining 476 articles were rechecked for relevance. There remained 34 full-text papers that were assessed for eligibility. Only 13 of these studies fulfilled the eligibility criteria to provide information on university library services in the pandemic era. PRISMA guidelines are followed in this study.
The findings of this systematic literature review contribute towards a better understanding of the impact of coronavirus on university library services. These are also useful for academic librarians to facilitate their patrons by improving their electronic resources during the pandemic situation of COVID-19. This study provides guidelines and systematic steps for evaluating the impact of the pandemic situation on university library services. This review also aids university libraries in making decisions on the adoption of digital and electronic services to support students’ e-learning programs. Through exploration and reflection, this review contributes to a newly emerging body of knowledge on university library services during the outbreak of coronavirus