Relationship of triglycerides/high density lipoprotein-cholesterol index with antioxidant defense and outstanding association with high sensitive c-reactive protein in Mexican subjects

"The TriGlycerides/High-Density Lipoprotein- Cholesterol (TG/HDL-C) ratio is a new index that has been proposed to estimate CardioVascular Risk (CVR). However, the relationship between this index with the antioxidant defense and inflammation is unknown. The aim of the study was to determine the relationship between the TG/HDL-C index with antioxidant defense and inflammation marker in Mexican subjects. Materials and Methods: In the study, Mexican subjects participated who were anthropometrically, biochemically, and clinically characterized. The TG/HDL-C index was calculated by dividing TG levels by HDL-C levels; a cut-off point >3 was considered CVR. The study subjects were divided into three groups: 1) subjects without CVR; 2) subjects with CVR, and 3) subjects with Type 2 Diabetes (T2D). In the subjects, we evaluated antioxidant defense by determine SuperOxide Dismutase (SOD) and Glutathione Peroxidase (GPx) activities, and high sensitive C-Reactive Protein (hsCRP) as inflammation marker"

Dry Eye Disease Association with Computer Exposure Time Among Subjects with Computer Vision Syndrome

Purpose: To assess the time of exposure to the computer and dry eye disease (DED) in subjects with computer vision syndrome (CVS).Methods: A cross-sectional study was conducted in office workers, computer users of both sexes, with an age range of 18– 45 years without comorbidities; we included 108 subjects divided into 3 groups according to the time of computer exposure in hours per day (H/D): 8 (n = 39). A specific questionnaire was applied to them on the exposure time and the type of visual display terminal (VDT) used, as well as the computer vision symptoms scale (CVSS17). DED was diagnosed with the Ocular Surface Disease Index (OSDI). Ocular surface damage and signs of DED were evaluated with the tear rupture time test (TBUT), the integrity of the ocular surface by ocular surface staining (OSS) and the production of the aqueous basal tear film using the Schirmer test.Results: Average computer exposure time, measured differently, was positively correlated with DED development. The computer exposure time measured in hours per year and TBUT showed a significant negative correlation (p < 0.001) (rho − 0.463). Years of computer exposure and staining of the ocular surface showed a significant positive correlation (p < 0 0.001; rho 0.404). The accumulated exposure time was negatively correlated with TBUT (p < 0.001; rho − 0.376) and positively with OSS (p < 0.001; rho 0.433). Schirmer test did not correlate with computer exposure time.Conclusion: The prolonged time of exposure to the computer in subjects with CVS was significantly correlated with the DED tests, in the different ways of measuring it; but not with the Schirmer test.Keywords: computer vision syndrome, dry eye disease

Dry eye disease association with computer exposure time among subjects with computer vision syndrome

"Computer vision syndrome (CVS) is defined as “The combination of eye problems and vision, associated with prolonged use of computers.”1 This term is used to describe the collection of visual, ocular and musculoskeletal symptoms that result from prolonged computer or visual display terminal (VDT) use. It may develop when a computer is used >3 hours per day or >30 hours per week.1,2 It is characterized by constant symptoms ocular, visual and musculoskeletal as asthenopia, ocular surface alterations, visual and extra-ocular alterations.1–4 It can be diagnosed in a standardized and reliable way with the computer-vision symptom scale questionnaire (CVSS17).5 This questionnaire include encompasses 15 visual and ocular symptoms as well as ocular surface alterations include dry, red, wet or irritated eye related with the development of the dry eye.5 Dry eye disease diagnosis, classification and severity assessment require multiple evaluations; Schirmer test, tear break-up time (TBUT), ocular surface staining (OSS) with sodium fluorescein,6 and the ocular surface disease index (OSDI) questionnaire are among the more frequently used"

Relationship of triglycerides/high density lipoprotein-cholesterol index with antioxidant defense and outstanding association with high sensitive C-reactive protein in Mexican subjects

"Background: The TriGlycerides/High-Density Lipoprotein- Cholesterol (TG/HDL-C) ratio is a new index that has been proposed to estimate CardioVascular Risk (CVR). However, the relationship between this index with the antioxidant defense and inflammation is unknown. The aim of the study was to determine the relationship between the TG/HDL-C index with antioxidant defense and inflammation marker in Mexican subjects"

Índice TG/HDL para identificar a sujetos con síndrome metabólico en población mexicana

"El índice triglicéridos/lipoproteína de alta densidad (TG/HDL) ha sido propuesto como un indicador de riesgo cardiovascular. En México, existe un estudio en adultos jóvenes que lo relaciona con resistencia a la insulina, pero no se ha definido un punto de corte que distinga a sujetos con síndrome metabólico. Objetivo: Determinar el punto de corte para el índice TG/HDL que identifique a sujetos con síndrome metabólico en población mexicana"