Influence of chemical fertilizers and bioinoculants on growth and yield of sunflower (Helianthus annuus L.)

The present study was conducted to investigate and compare the effect of applying various levels of chemical fertilizers and bioinoculants on the growth and yield of sunflower during the 2017-2018 crop year in Hamedan, Iran. This study was executed as two factorial experiments, as a randomized complete block design in three repetitions. Chemical fertilizers containing nitrogen (N) and phosphorus (P) were used in the first experiment, and nitrogen-fixing (NI) and phosphate-solubilizing (BI) bioinoculants were used in the second experiment. The experimental treatments included applying a urea fertilizer (N0=0, N1=45, N2=90 kg pure nitrogen/ha) and a triple superphosphate (P0=0, P1=40, P2=80 kg pure phosphorus/ha), as well as a nitroxin biofertilizer (NI0=0, NI1=0.5, NI2=1 L/ha) and a biophosphorus (BI0=0, BI1=0.5, BI2=1 L/ha). The results indicated that the highest levels of leaf dry weight, number of seeds per head, head diameter, head weight, seed yield, and the plant\u27s biological yield were obtained for the chemical treatment (N2P2) and biological treatment of (NI2BI2). Group comparisons between the chemical and biological treatments did not show a significant difference for any of the studied characteristics, therefore, the results of this study conclude that the investigated levels of bioinoculants could be appropriate alternatives to chemical fertilizers

A Study on Angular Distribution of THz Radiation Driven by Two-Color Laser-induced Microplasma

We present an analytical method to study the angular distribution of THz radiation driven by two-color laser-induced microplasma in nitrogen gas. Directionally dependent temporal waveforms of the radiated THz pulse is calculated. To do so, we have extended the photo-current model to calculate three-dimensional distribution of the photo-induced current from which the far field THz radiation is computed. We have also studied the effect of optical polarization state and phase difference on the angular distribution of radiation. Our study shows that for two orthogonally-polarized colors, not only THz polarization state, but also the angular distribution of THz radiation is mostly influenced by the second optical harmonic. The possibility of rotating the angular radiation pattern around the axis of the laser propagation is illustrated for circularly-polarized laser drivers by changing the optical phase difference

Effect of troxerutin on serum glucose level and lactate dehydrogenase activity after exhaustive swimming in male rats

زمینه و هدف: ورزش وامانده ساز منجر به آسیب عضلانی و کاهش منابع انرژی نظیر گلوکز می‌شود. هدف مطالعه حاضر بررسی اثر مکمل تروگزروتین بر سطح سرمی گلوکز و فعالیت لاکتات دهیدروژناز متعاقب شنا وامانده ساز در موش‌های صحرایی نر بود. روش بررسی: در این مطالعه تجربی، 32 سر موش صحرایی نر نژاد ویستار به صورت تصادفی به 4 گروه کنترل، ورزش + 75 میلی گرم بر کیلوگرم، ورزش+ 150 میلی گرم بر کیلوگرم و ورزش + 300 میلی گرم بر کیلوگرم تیمار تروگزروتین تقسیم شدند. کلیه حیوان‌ها به مدت 30 روز تمرین شنا (5 بار در هفته) انجام دادند. تروگروتین به صورت خوراکی روزانه به مدت 30 روز تجویز شد. در روز سی‌ام ورزش شنا وامانده ساز انجام و سطح سرمی گلوکز و فعالیت لاکتات دهیدروژناز اندازه گیری شد. یافته ها: نتایج نشان داد که مکمل تروگزروتین به طور معنی‌داری سطح سرمی گلوکز را در مقایسه با گروه کنترل افزایش می‌دهد (001/0>P) و همچنین فعالیت لاکتات دهیدروژناز در گروه ورزش + تروگزروتین (300) در مقایسه با گروه‌های کنترل و ورزش + تروگزروتین )150 میلی گرم بر کیلوگرم( کاهش یافت (05/0>P). نتیجه گیری: مطالعه حاضر نشان داد که تروگزروتین می‌تواند تأثیر قابل توجهی در کاهش آسیب عضلانی ناشی از ورزش شنا وامانده ساز داشته باشد

Light at Night Exposure Effects Differentiation and Cell Cycle in Rat Liver with Autonomic Nervous System Denervation

Introduction: Exposure to the artificial light at night (LAN) effect human health and causes several functional modification in body. Obesity, diabetes, and hormonal changes are reported after LAN in humans. Aim of this study is highlighting critical features of gene expression changes in liver of rats which are received autonomic nervous system.Methods: Liver gene expression profiles of 5 male Wistar rats that were received a sympathetic plus parasympathetic hepatic denervation and 1 hour expose light at night (LAN) from Gene Expression Omnibus (GEO) are compared with controls. The significant differentially expressed genes (DEGs) are screened by protein-protein interaction (PPI) network analysis STRING database (an application of Cytoscape software). CuleGO and CleuDedia the two applications of Cytoscape software were used for more analysis. Results: Among 250 DEGs, 173 genes characterized genes with fold change more than 2 plus 100 added relevant genes were included in the PPI network. Analysis of the main connected component (MCC) led to introduce 15 hubs and 15 bottlenecks. CCT2, COPS7A, KAT2A, and ERCC1were determined as hub-bottlenecks. Among hubs and bottlenecks, DHX15, KAT2A, CCT2, HSP90AB1, CCNE1, DHX16, LSM2, WEE1, CWC27, BAZ1B, RAB22A, DNM2, and DHX30 were linked to the each other’s by various kinds of actions. CCT2 and KAT2A, the two hub-bottlenecks are included in the interacted genes in the action map. Four classes of biological terms including negative regulation of non-motile cilium assembly, negative regulation of transforming growth factor beta activation, alpha-tubulin acetylation, and histamine-induced gastric acid secration were identified as the critical involved biochemical pathways and biological processes.Conclusion: Several essential functions as like differentiation, cell cycle, ribosome assembly, and splicing are affected by LAN in rat liver with autonomic nervous system denervation.

Attacking Massive MIMO Cognitive Radio Networks by Optimized Jamming

Massive multiple-input multiple-output (MaMIMO) and cognitive radio networks (CRNs) are two promising technologies for improving spectral efficiency of next-generation wireless communication networks. In this paper, we investigate the problem of physical layer security in the networks that jointly use both technologies, named MaMIMO-CRN. Specifically, to investigate the vulnerability of this network, we design an optimized attacking scenario to MaMIMO-CRNs by a jammer. For having the most adversary effect on the uplink transmission of the legitimate MaMIMO-CRN, we propose an efficient method for power allocation of the jammer. The legitimate network consists of a training and a data transmission phase, and both of these phases are attacked by the jammer using an optimized power split between them. The resulting power allocation problem is non-convex. We thus propose three different efficient methods for solving this problem, and we show that under some assumptions, a closed-form solution can also be obtained. Our results show the vulnerability of the MaMIMO-CRN to an optimized jammer. It is also shown that increasing the number of antennas at the legitimate network does not improve the security of the network

Valproate Effects on Chemophysical Properties of Human Serum Albumin

Albumin has a fundamental role in human body. Its main tasks in blood are to regulate osmotic blood pressure, maintaining the pH, and transporting metabolites and drugs throughout the vascular system.  Pharmacological studies of the interaction of drugs on HSA are important due to structural and functional changes of this vital protein; thus, here in this research the effect of valproate as a common drug for epilepsy disorders is evaluated in the presence of hexadecyl pyridinium bromide (HPB) as a positive surfactant in normal and fever condition. Electrochemical method was used to investigate the binding number of HPB molecules to HSA in the absence and presence of valproate by evaluating the concentration of free HPB in 37oC and 42oC temperatures. HSA affinity for valproate binding studied via ligand binding process for normal and fever temperatures. The findings indicate that, there is a significant difference in valproate binding to albumin at physiological and pathological temperatures. The consequences are the same in the presence of HPB; in other words, HSA binding tendency to HPB in the presence of valproate was totally altered because of HSA major conformational changes in fever condition. In conclusion, corrected dosage of valproate is needed for fever condition relative to normal temperature and the patients under prescription of different medications in fever condition should have different orders due to the interferences of drugs.

Herbal remedies and medicine; introducing some Iranian plants

     The overall goal of this review is to discuss the potential efficacy of herbal treatments. Plants are considered among the main sources of biologically active chemicals. Plant based drugs usage in our past decay became very renowned due to their fewer side effects and being less expensive than chemical ones. Recently, more abrupt tendency in this field has been increased. Furthermore, advances in molecular and cellular determinations revealed effective properties of these herbal components. Some plants extracts have shown multi-functional properties such as anti-oxidant, anti-amyloid, antimicrobial, and anti-inflammatory; further studies, besides,   are required for detailed chemical characterization and more extensive biological evaluation of the most active ingredients. In summary, herbals can be considered as novel therapeutic approach against wide range of diseases. This review article draws the attention to some species of plants possessing biological activities on human health

The Highlighted Role of GAPDH and Nitric-Oxide Synthase Regulator Activity in Proton Beam Irradiated Melanoma BLM Cells

Introduction: Human melanoma is a type of invasive tumor that its treatments is challenging. To better understand the proton irradiation mechanisms as one of the widely applied therapy for this type of cancer, bioinformatics analysis of proteomics outcome could be beneficial.Methods: Protein-protein interaction network analysis of differentially expressed proteins (DEPs) of melanoma BLM (BRO Lung Metastasis) cells in the treatment of 3 Gy dosage proton therapy is performed in this study via Cytoscape V.3.7.2. and its integrated plug-ins.Results: A number of 18 DEPs were searched for network constructions and limited numbers of (query +neighbor proteins) were found central. The hub-bottlenecks or in the other words, central nodes were GAPDH, ACTB, ALB, AKT1, TP53, and EGFR. The fist mentioned proteins is from DEPs. Enrichment analysis of these elements identified as nitric-oxide synthase regulator activity and positive regulation of norepinephrine uptake that may be key in the mechanisms of proton therapy.Conclusion: In conclusion, the identified central nodes (EGFR, TP53, ALB, AKT1, GAPDH, and ACTB) and the related biological terms consist with the nature of melanoma and also radiation effects.

Impacts of Logging-Associated Compaction on Forest Soils: A Meta-Analysis

Soil compaction associated with mechanized wood harvesting can long-lastingly disturb forest soils, ecosystem function, and productivity. Sustainable forest management requires precise and deep knowledge of logging operation impacts on forest soils, which can be attained by meta-analysis studies covering representative forest datasets. We performed a meta-analysis on the impact of logging-associated compaction on forest soils microbial biomass carbon (MBC), bulk density, total porosity, and saturated hydraulic conductivity (Ksat) affected by two management factors (machine weight and passage frequency), two soil factors (texture and depth), and the time passed since the compaction event. Compaction significantly decreased soil MBC by −29.5% only in subsoils (>30 cm). Overall, compaction increased soil bulk density by 8.9% and reduced total porosity and Ksat by −10.1 and −40.2%, respectively. The most striking finding of this meta-analysis is that the greatest disturbance to soil bulk density, total porosity, and Ksat occurs after very frequent (>20) machine passages. This contradicts the existing claims that most damage to forest soils happens after a few machine passages. Furthermore, the analyzed physical variables did not recover to the normal level within a period of 3–6 years. Thus, altering these physical properties can disturb forest ecosystem function and productivity, because they play important roles in water and air supply as well as in biogeochemical cycling in forest ecosystems. To minimize the impact, we recommend the selection of suitable logging machines and decreasing the frequency of machine passages as well as logging out of rainy seasons especially in clayey soils. It is also very important to minimize total skid trail coverage for sustainable forest management

New Molecular Aspects of Cardiac Arrest; Promoting Cardiopulmonary Resuscitation Approaches

Introduction: Cardiopulmonary resuscitation (CPR) is a method to improve survival of patients with cardiac arrest. This study aimed to identify the key genes affected five minutes after cardiac arrest, hoping to elevate the efficacy of CPR.Methods: In this bioinformatics study differentially expressed genes of six pigs were downloaded from GEO and screened. The significant and characterized genes were analyzed via calculating fold change and protein-protein interaction (PPI) networks. The crucial nodes were determined based on centrality parameters and their related biological processes were investigated via ClueGO.Results: 17 significant up-regulated (LogFC ≥ 2) and 22 down-regulated (LogFC < -0.5) genes were detected. Transthyretin (TTR logFC = 4.59) and Gonadotropin-releasing hormone receptor (GNRHR logFC = 3.84) had higher logFC among up-regulated and down-regulated genes, respectively. The critical genes including four up-regulated and five down-regulated genes were detected from network analysis. GNRHR and Prolactin precursor (PRL) were among the most important down res 5 minutes after cardiac arrest and Beta-2 adrenergic receptor and Cadherin-1 were among the most important up regulated gens. Conclusion: The introduced potential biomarkers could reveal a new molecular aspect for CPR performance and pituitary gland protection was highlighted in this respect.