The effectiveness of choice theory group therapy of glasser on divorced women self-efficacy

The purpose of the present research was to study the effectiveness of choice theory group therapy by William Glasser (1998) on divorced women self-efficacy between 18 to 23 years old. The research was semi experimental type along with pretest-past test. Using self-efficacy questionnaire (SGSES), 30 women who was of low self-efficacy were chosen on simple random and were randomly divided into experimental and control groups. Experiment group received 8 sessions treatment of Choice Theory group therapy for two months while the control group did not receive any training. After receiving training, self-efficacy was measured for next time. The collected data was analyzed by SPSS v.21 and by applying multivariate analysis covariance. The results revealed self-efficacy (P<0.05) significant effect. The present investigation clarified choice theory group therapy increased divorced women self-efficacy

Prevalence of chromosomal aberrations in couples with recurrent miscarriages in the city of Mashhad, Iran: a cross-sectional study

Background: Recurrent miscarriage is defined as two or more recurrent spontaneous miscarriages. Several causes have been suggested, among which, chromosomal abnormalities in couples is considered to have a role in this regard. However, its significance varies among different populations. The present study was carried out to evaluate the prevalence of chromosomal aberrations in couples with recurrent miscarriages in the city of Mashhad.Materials and Methods: A retrospective study was performed on patient records at Medical Genetics Clinic of Imam Reza hospital in Mashhad (north-east of Iran) between 2003 and 2006.Results: Of 151 records of recurrent miscarriages, 59 couples had undergone Karyotyping testing. Among those who had Karyotyping results, only one (1.7%) had chromosomal abnormality. The observed abnormality was associated with chromosome 9 inversion. The prevalence of consanguineous marriage among these couples was 59.0%.Conclusion: In our study, unlike similar studies in other countries, the prevalence of chromosomal abnormalities was much lower. This could be interpreted either due to laboratory errors in our clinic or the real reduction in the association of chromosomal abnormalities with recurrent miscarriages in our population. Regarding our data, it seems that, at least among our population, costly Karyotyping testing is not necessary to predict further miscarriages or it could be limited to fewer cases having other associated factors

Correlation of dysoxia metabolism markers with trauma scoring systems in multiple trauma patients admitted to the emergency department: A cross-sectional observational study

Background: All the trauma scoring systems (TSSs) have some limitations, and none is useful for patient monitoring. Recently, investigators have tried to modify the TSSs to improve their use. Aims: This study was conducted to determine whether any correlation exists between dysoxia metabolism markers (DMMs), including venous base deficit (BD) and HCO3level with different TSSs. Materials and Methods: In this cross-sectional study, all multiple trauma patients admitted to the emergency department were eligible. Blood samples for venous blood gas analysis were taken at the onset of resuscitation process. TSSs, including trauma index (TI), abbreviated injury score (AIS), Injury Severity Score (ISS), Revised Trauma Score (RTS), and Trauma Score-ISS (TRISS), were calculated for the patients. Spearman's rank correlation coefficient test was applied to find the association between the independent variables. Results: A total of 285 patients with a mean age of 33.37 ± 15.29 fulfilled the inclusion criteria, of which, 211 cases (74.0) were male. Statistical analysis revealed that there was a correlation between TI and HCO3level (P = 0.0001, r = 0.37) and also TI and BD (P = 0.0001, r = 0.47). Furthermore, there was an indirect correlation between AIS and ISS with HCO3and BD levels and the direct correlation between RTS and TRISS with HCO3and BD levels. Conclusion: It is likely that there is a statistical correlation, although weak, between TSSs with DMMs, including HCO3and BD level

Efficacy of Integrating Stress Coping Skills Training with Detoxification on Social Adjustment of Addicted Women

Background: Addiction as a biopsychosocial problem has been dramatically increased in our country. Adverse consequences of the addiction in women have been shown to be more than men, which in turn can affect family members’ health and wellbeing. The current study examined the efficacy of stress coping skills training in addicted women referring to an outpatient centre of addiction prevention located in Welfare Organization of Gorgan, Iran. Methods: 30 women with low levels of social adjustment measured by Social Adjustment Scale were randomly assigned to coping skills training with detoxification treatments (experimental) or detoxification alone groups. Both groups (N = 15) completed pre-post assessments of Bell’s adjustment Inventory. Experimental group received coping skills training program in ten sessions, each session last 90 minutes. Findings: Social adjustment was considerably improved more in addicted women who followed coping skills training program with detoxification treatment in comparison with the women who was undergone only detoxification treatment.Conclusion: Skills training program can help addicted women to better cope with their adjustment problem and these skills should be integrated into detoxification programs for this population.Keywords: Addiction, Detoxification, Stress, Coping skills training, Social adjustment

Ketamine Sub-Dissociative Dose Vs. Morphine Sulfate for Acute Pain Control in Patients with Isolated Limb Injuries in the Emergency Department: A Randomized, Double-blind, Clinical Trial

Objective: To compare the ketamine efficacy at a sub-dissociative morphine dose to reduce pain in isolated limb traumatic injuries. Methods: A double-blind randomized clinical trial study was carried out on patients referred to emergency departments (EDs) due to isolated limb traumatic injuries. Eligible patients were divided into two groups which one group received 0.1 mg/kg ketamine and the other group received 0.05 mg/kg morphine, intravenously. An observed side effect includes pain scores and vital signs were recorded at baseline of every 5 minutes for 30 minutes. Results: Totally, 73 patients with the mean age of 32.9±10.4 were enrolled of whom 59 (80.8%) individuals were men. The baseline characteristics difference of the two study groups was not statistically significant. The results showed that the change of mean pain score was -6.2 (95% CI: -5.72 to -6.69) points in the group receiving ketamine compared to -5.8 (95%CI: -5.15 to – 6.48) in the group who were administered morphine. At all assessed checkpoints, the pain mean score was lower in the ketamine group than in the morphine group (p <0.05); the mean of total pain reduction was greater in the ketamine group during the observation period compared with patients who received morphine (p=0.002). Conclusion: The study findings suggest that the sub-dissociative ketamine efficacy in controlling of the acute pain is not lower than morphine sulfate in patients with isolated limb trauma in ED’s. Thus, it can be considered as a safe and effective alternative approach

A potential hypothesis for 2019-nCoV infection therapy through delivery of recombinant ACE2 by red blood cell-hitchhiking

A novel infectious disease, caused by 2019 Novel Coronavirus (2019-nCoV) is responsible for the recent outbreak of severe respiratory disease. The 2019-nCoV spread rapidly and reaching epidemic proportions in many countries of the world. ACE2 was identified as a key receptor for 2019-nCoV infections. Excessive form of soluble ACE2 rescues cellular ACE2 activity which has a protective role in acute lung failure and neutralizes the virus. The short half-life of ACE2 is a major limitation to its practical application. Nanoparticle-based drug delivery systems are one of the most widely investigated approaches for developing novel therapies for a variety of diseases. Nevertheless, nanoparticles suffer from the rapid removal from the bloodstream by the reticuloendothelial system (RES). A noncovalent attachment of nanoparticles to RBCs increases their half-life in blood and allows transient accumulation in the lungs, while decreases their uptake by the liver and spleen. Connecting the recombinant ACE2 into the surface of nanoparticles that were attached to RBCs can be a potential therapeutic approach for 2019-nCoV infection through increasing their lung targeting to naturalize the virus and also acting as a bioreactor in the blood circulation to decrease serum level of Angiotensin II and protects lungs from injury/ARDS

Study Guides : Effective Tools to Improve Self-Directed Learning Skills of Medical Students

We would like to thank the participants for contribution in this study.Peer reviewedPublisher PD

The comparison of selected statistical indicators of a hospital before and after the implementation of health reform plan: Isfahan-2015

زمینه و اهداف: مرحله سوم طرح تحول نظام سلامت با ابلاغ کتاب ارزش نسبی خدمات و مراقبت‌های سلامت اجرایی شد. با توجه به تأثیر این کتاب بر عملکرد بیمارستان‌ها و مراکز آموزشی درمانی، مطالعه حاضر با هدف تعیین ومقایسه نشانگرهای آماری منتخب یک مرکز آموزشی درمانی قبل و بعد از اجرای مفاد این کتاب انجام گرفت. مواد و روش‌ها: مطالعه توصیفی- تحلیلی حاضر، به صورت مقطعی در سال 1394 انجام شد. نشانگرهای آماری، با بررسی فرم‌های فعالیت مرکز و مراجعه به مدیریت آمار دانشگاه علوم پزشکی اصفهان، با کسب مجوز و رعایت اصل محرمانگی اطلاعات، جمع‌آوری و با نرم افزار آماري SPSS &nbsp;(ويرايش 17) تحلیل شد. مقایسه نشانگرها توسط آزمون‌های آماری برای نمونه‌های زوج شده انجام و در سطح معنی‌داری 0/05&gt;P تحلیل شد. یافته‌ها: ابلاغ کتاب ارزش نسبی، موجب افزایش معنادار در نشانگرهای درصد اشغال تخت، تخت روز اشغالی، میانگین مدت اقامت بیمار و تعداد مرگ و میر و کاهش معنادار در نشانگرهای فاصله چرخش تخت و چرخش اشغال تخت شد. در نشانگرهای میانگین تعداد بستری شدگان و ترخیص شدگان افزایش و در نشانگرهای تعداد مراجعین اورژانس و سزارین کاهش معنادار مشاهده شد. نتیجه‌ گیری: اجرای کتاب مذکور، بر برخی از نشانگرها (درصد اشغال تخت، تخت روز اشغالی، تعداد سزارین) تأثیر گذار و بر دیگر نشانگرها (تعداد بستری شدگان، مراجعین سرپایی، مراجعین اورژانس، ترخیص شدگان و تعداد اعمال جراحی) بدون تأثیر بوده است. البته تعمیم نتایج مطالعه به سایر بیمارستان‌ها، نیازمند مطالعه گسترده‌تری می‌باشد.Background and Aim: The third phase of health reform plan in Iran came into force since the announcement of the book named value of the notification. Due to the influence of this book on hospitals performance,this study aimed to determine and compare the selected statistical indicators of a teaching hospital before and after the implementation of the contents of this book.Materials and Methods: The present cross-sectional descriptive-analytical study was conducted in 2015. Data (statistical indicators) were collected, with the permission and considering the confidentiality of information, through reports review and on-site visiting and analyzed using SPSS (version 17) software.The comparison of selected indicators between paired samples were performed. Correlations were considered significant at α=0.05.Results: Announcement of the value of the notification book resulted in a statistically significant increase in bed occupancy ratio, occupied bed day, average length of stay, and number of hospital death and also a significant decrease of bed turnover interval and rate. Furthermore, a significant increase of inpatients andoutpatients visits and significant decrease of emergency visits and caesarean were also observed.Conclusion: Implementation of the aforementioned book significantly affected some statistical indicators (bed occupancy ratio, occupied bed day, and caesarian), but it has no significant effect on other statistical indicators (inpatients and outpatients visits, emergency visits and number of surgeries). However, extendingthe results of this study to other hospitals requires more extensive studies

Efficacy of Integrating Stress Coping Skills Training with Detoxification on Social Adjustment of Addicted Women

Abstract Background: Addiction as a biopsychosocial problem has been dramatically increased in our country. Adverse consequences of the addiction in women have been shown to be more than men, which in turn can affect family members’ health and wellbeing. The current study examined the efficacy of stress coping skills training in addicted women referring to an outpatient centre of addiction prevention located in Welfare Organization of Gorgan, Iran. Methods: 30 women with low levels of social adjustment measured by Social Adjustment Scale were randomly assigned to coping skills training with detoxification treatments (experimental) or detoxification alone groups. Both groups (n = 15) completed pre-post assessments of Bell’s adjustment Inventory. Experimental group received coping skills training program in ten sessions, each session last 90 minutes. Findings: Social adjustment was considerably improved more in addicted women who followed coping skills training program with detoxification treatment in comparison with the women who was undergone only detoxification treatment. Conclusion: Skills training program can help addicted women to better cope with their adjustment problem and these skills should be integrated into detoxification programs for this populatio