Bazı sporcu sporcu protein tozlarının protein içeriği ve sindirilebilirliği

The aim of this study is to determine the protein contents and the digestion rates in in vitro conditions by using Dumasmethod of different types of protein powders which are widely used as nutritional supplements by athletes. In the researchprotein and digestion levels of whey, bovine milk casein, soy, egg white, beef protein, pea protein powders weredetermined. The protein content reported in the labels of the protein powder samples examined in the study and the proteinlevels determined in the study for whey, casein, soy, meat, egg white, pea powders and standard were respectively; 76-72.49, 86-83.01, 91-76.61, 88-99.28, 85-85.89, 84-77.32, 91.4-90.42. According to data, the determined protein contents ofbovine milk casein which was used as standard and egg white powder were in agreement with the label information; theamount of protein contained in whey powder, casein powder, soy powder, pea powder was lower than the value indicatedon the label; and meat powder contained protein above the level indicated in the label information. According to thefindings and statistical evaluations obtained from the digestion experiments, the highest digestion degree was in meatpowder protein (66.28%), the second was casein powder (60.61%) and followed by milk casein (56.88%), whey proteinpowder (54.42%) and pea protein powder (53.67%), soy protein powder (43.68%), lowest digestion rate was in egg proteinpowder (36.57%). The difference between the groups was statistically significant (p &lt;0.05). As a result of the research, it isimportant to note that protein powders sold as sports food supplements should be expressed correctly in the labelinformation of the protein contents, which may lead to misleading of the consumer. It is underlined the importance ofinforming the consumer about the methods used in the production of protein powders since it is associated with digestibilityand protein conversion to body protein.</p

A case of Severe Low-dose Methotrexate-induced Toxicity

Methotrexate (MTX) is an antimetabolite which competitively inhibits dihydrofolic acid reductase; inhibits purine and thymidylic acid synthesis, which in turn interferes with DNA synthesis, repair, and cellular replication. MTX is a good treatment option for neoplastic, rheumatic and dermatological diseases. However, rarely, may cause side effects, such as agranulocytosis and bone marrow suppression, mucosal tissue inflammation and necrotic changes, liver cell necrosis and hepatic cirrhosis, pulmonary fibrosis, and severe renal dysfunction. Herein, we report a 67-year-old female patient with a history of psoriasis for 15 years and MTX 15 mg/sc/week use for 8 years who was admitted due to the complaints of pancytopenia, mucositis and ulcers on psoriatic plaques despite low-dose MTX use. We present this case to remind that MTX toxicity might occur with low-dose MTX usage and to draw attention to various factors that facilitate the low-dose MTX toxicity, such as age, renal insufficiency, low albumin levels, infections, proton pump inhibitors and non-steroidal anti-inflammatory drugs

A Retrospective Evaluation of Patients with Recurrent Aphthous Stomatitis

Aim: To determine the factors in the etiology of recurrent aphthous stomatitis (RAS) and to evaluate patients in the terms of RAS associated systemic disorders especially Behçet’s disease. Methods: Patients with RAS, who were followed up in Bartın State Hospital Dermatology Clinic between July 2013 and April 2015, were retrospectively evaluated. Results: A total of 123 patients (86 female, 37 male) were included in this study. Thirteen (106%) patients were children. The mean age of patients was 34.5±14.7 years (range: 8-69 years). Minor aphthous somatitis was the most frequent clinical type (68.3%). Family history was positive in 52.8% of patients. The triggering factors in the etiology of RAS were stress (54.5%), trauma (40.2%), gingivitis (29.3%), food (9.8%), medicines (5.7%), menstruation in female patients (3.3%), and throat infections (2.4%). Nutritional deficiencies were found in 39% of patients. There was a statistically significant difference in attack frequency (p=0.017) and throat infection history (p=0.029) between adults and pediatric patients. Fourteen (11.4%) patients were diagnosed with Behçet’s disease. When we compared the RAS patients diagnosed with Behçet’s disease and the other RAS patients, a significant difference was found in pathergy test (p<0.001) and ferritin levels (p=0.020). Conclusion: Patients with RAS should be followed up for a long time for systemic disorders, especially for Behçet’s disease, accompanying RAS

İzmir'de bir Levanten ailesi : Baba Ailesi

Ankara : İhsan Doğramacı Bilkent Üniversitesi İktisadi, İdari ve Sosyal Bilimler Fakültesi, Tarih Bölümü, 2018.This work is a student project of the Department of History, Faculty of Economics, Administrative and Social Sciences, İhsan Doğramacı Bilkent University.The History of Turkey course (HIST200) is a requirement for all Bilkent undergraduates. It is designed to encourage students to work in groups on projects concerning any topic of their choice that relates to the history of Turkey. It is designed as an interactive course with an emphasis on research and the objective of investigating events, chronologically short historical periods, as well as historic representations. Students from all departments prepare and present final projects for examination by a committee, with 10 projects chosen to receive awards.Includes bibliographical references (pages 14-15).by İbrahim Mert Öztürk

Nineteen-year retrospective evaluation of pemphigus in a single dermatology centre in Istanbul, Turkey

WOS: 000519592400024Introduction: Pemphigus is an autoimmune intra-epidermal bullous disease of the skin and mucosae. Aim: To retrospectively evaluate the course, prognosis and clinical features of pemphigus. Material and methods: The files of 196 pemphigus patients admitted to our clinic between December 1995 and December 2014 were collected and analysed. Results: The male to female ratio among patients was 1 : 1.88. Pemphigus vulgaris (PV) was the most common clinical variant observed in 175 (89.3%) of the patients, followed by pemphigus foliaceus (PF) in 14 (7.1%) of the patients. The mean patient age at disease onset was 50 years. PV presented itself as skin lesions in 55 (31.4%) of the patients and as oral mucosa lesions in 120 (68.6%) of the patients. Complete remission and treatment withdrawal were obtained in 112 (57.1%) of the patients, for a mean period of 2.91 +/- 2.66 years (range: 4 months to 13 years). The mortality rate was 6%, and relapse occurred in 16 (14.3%) of the patients for a mean relapse period of 2.15 +/- 1.88 years (range: 6 months to 7 years). Mucocutaneous pemphigus (MCP) was the major clinical pattern observed in 96 (49%) of the patients. Conclusions: Within our study population, pemphigus predominately affected females, and the most common clinical variant was PV, a subtype that frequently occurs in middle-aged individuals. MCP was the most common clinical pattern. Although MCP and higher doses of corticosteroids were needed to control pemphigus, they did not seem to influence the prognosis

Case of olmsted syndrome with essential thrombocytosis misdiagnosed as acrodermatitis enteropathica

Olmsted syndrome is a rare genodermatosis. Palmoplantar keratoderma and periorificial keratodermic plaques are the most important clinical findings. Additional findings associated with a large number of systems may accompany such as teeth, nail deformities, alopecia, mental retardation, and bone-joint anomalies. Therefore, it is difficult to make a differential diagnosis from other palmoplantar keratodermas. It also needs to be differentiated from acrodermatitis enteropathica because of periorificial plaques. The absence of regression in lesions with zinc treatment excludes this disease. We present here an Olmsted syndrome case with essential thrombocytosis for the first time

The multidisciplinary evaluation of dermatosis seen after Van earthquake

Objective: In this study, we aimed to evaluate the patients with dermatological diseases those were observed and treated and the referred to the hospital for dermatosis by the dermatologists, family physicians, plastic surgeons and orthopedists that worked in 10 day rescue mission in Van region. Methods: Totally 380 patients (139 female, 241 male) with dermatological problems referred to Van Region Hospital were evaluated by orthopedists, family physicians, plastic surgeons and dermatologists between 12-23 November 2011. Patients were divided into two groups; Group A consisted of patients whose complaints started before the earthquake and group B consisted of patients whose complaints started after the earthquake. The two groups were compared for dermatological diseases. Results: Totally 380 patients (139 female, 241 male) were evaluated. There were 151 and 229 patients in Group A and B, respectively. The mean age of patients was 30 ± 18 and 28 ± 17 in Group A and B, respectively. The most observed dermatological diseases in group A were erythemasquamose diseases (% 27.1) (eczema, mycosis fungoides, xeroderma, atopic dermatitis, seborrheic dermatitis, figured erythema), and in group B were bacterial infections (%27.5). Conclusion: Nonhygienic conditions (snow, cold, mud) leads to bacterial skin infection and traumatic skin lacerations. Helps those made arbitrarily may cause tent fires which giving rise to physical dermatosis

Pigmented purpuric dermatosis: Ten years of experience in a tertiary hospital and awareness of mycosis fungoides in differential diagnosis

Background: Pigmented purpuric dermatoses (PPD) can clinically mimic many diseases. Histopathology provides a definitive diagnosis. The aim of the study is to reveal the features of patients with PPD and to determine the disease frequency in the differential diagnosis, especially mycosis fungoides (MF). Methods: We retrospectively reviewed records of patients with PPD admitted to our hospital from January 2010 to May 2019. We studied the histopathological features of 127 patients, and performed pattern analysis on cases with a confirmed histopathologic diagnosis of PPD. Among the cases presenting with clinical features of PPD, but displaying different histopathological diagnoses, we focused on MF and tried to clarify the features of PPD-like MF. Results: Overall, 389 patients were admitted to our hospital with PPD symptoms. Of them, 262 patients were diagnosed clinically and a histopathological examination was performed in 127 patients. Of 127, 87 were diagnosed with PPD, and in the remaining 40, non-specific features (9.4%), vasculitis (6.2%), pityriasis rosea (4.7%), MF (3.9%), suspected-MF (1.5%), and other dermatoses (%5.5) were detected. The biopsy findings of two patients showed PPD, but during follow-up, the diagnosis of MF was established. Conclusions: MF should be included in the differential diagnosis of PPD cases presenting with longstanding and widespread involvement

Could "islets of sparing" be a clue for neutral lipid storage disease with ichthyosis in patients with congenital ichthyosiform erythroderma?

The prevalent form of ichthyosis in neutral lipid storage disease (NLSDI) is nonbullous congenital ichthyosiform erythroderma (CIE) characterized by fine, whitish scales on erythematous skin over the whole body. Here, we report a late-diagnosed, 25-year-old woman with NLSDI presenting with diffuse erythema and fine whitish scales throughout the body with patches of apparently normal skin, "islets of sparing" on her lower extremities. We observed that the size of the normal skin islets changed with time, and even the entire lower extremity was covered with erythema and desquamation like the rest of the body. Frozen section histopathological examinations were made from lesional skin and normal-looking skin; no difference was observed in terms of lipid accumulation. The only noticeable difference was the thickness of the keratin layer. In CIE patients, observation of patches of apparently normal skin or "islets of sparing" might be a clue for NLSDI to be distinguished from other CIE conditions