Magnetic field effects on the electroluminescence of organic light emitting devices: A tool to indicate the carrier mobility

The magnetoelectroluminescence (MEL) of organic light emitting devices with a N, N′ -bis(l-naphthyl)- N, N′ -diphenyl- 1, l′ -biphentl- 4, 4′ -diamine:tris-(8-hydroxyquinoline) aluminum (NPB: Alq 3) mixed emission layer (EML) has been investigated. We find that MEL is maximized when the volume ratio of NPB of the mixed EML reaches 30% and the EML thickness is 40 nm. The features of MEL under various magnetic field strengths are insensitive to the change in EML thickness and mixing ratio. Meanwhile, MEL has a close relationship with the carrier mobility. We have conducted a theoretical study to further verify the relationship. Our experimental and theoretical results confirm that MEL can function as a tool to indicate the mobility. © 2010 American Institute of Physics.published_or_final_versio

Tuning the vertical location of helical surface states in topological insulator heterostructures via dual-proximity effects

In integrating topological insulators (TIs) with conventional materials, one crucial issue is how the topological surface states (TSS) will behave in such heterostructures. We use first-principles approaches to establish accurate tunability of the vertical location of the TSS via intriguing dual-proximity effects. By depositing a conventional insulator (CI) overlayer onto a TI substrate (Bi2Se3 or Bi2Te3), we demonstrate that, the TSS can float to the top of the CI film, or stay put at the CI/TI interface, or be pushed down deeper into the otherwise structurally homogeneous TI substrate. These contrasting behaviors imply a rich variety of possible quantum phase transitions in the hybrid systems, dictated by key material-specific properties of the CI. These discoveries lay the foundation for accurate manipulation of the real space properties of TSS in TI heterostructures of diverse technological significance

Topological modes bound to dislocations in mechanical metamaterials

Mechanical metamaterials are artificial structures with unusual properties, such as negative Poisson ratio, bistability or tunable vibrational properties, that originate in the geometry of their unit cell. At the heart of such unusual behaviour is often a soft mode: a motion that does not significantly stretch or compress the links between constituent elements. When activated by motors or external fields, soft modes become the building blocks of robots and smart materials. Here, we demonstrate the existence of topological soft modes that can be positioned at desired locations in a metamaterial while being robust against a wide range of structural deformations or changes in material parameters. These protected modes, localized at dislocations, are the mechanical analogue of topological states bound to defects in electronic systems. We create physical realizations of the topological modes in prototypes of kagome lattices built out of rigid triangular plates. We show mathematically that they originate from the interplay between two Berry phases: the Burgers vector of the dislocation and the topological polarization of the lattice. Our work paves the way towards engineering topologically protected nano-mechanical structures for molecular robotics or information storage and read-out.Comment: 13 pages, 6 figures; changes to text and figures and added analysis on mode localization; see http://www.lorentz.leidenuniv.nl/~paulose/dislocation-modes/ for accompanying video

Surface processes and kinetics of CO2 reduction on Pt(100) electrodes of different surface structure in sulfuric acid solutions

The reduction of CO2 on a Pt(100) electrode in CO2 saturated 0.5 M H2SO4 solutions was studied by in situ FTIR reflection spectroscopy and a programmed potential step technique. Different surface structures of Pt(100) electrode were prepared by different treatments including fast potential cycling (200 V s(-1)) for a known time. The Pt(100) surface was characterized by a parameter gamma that designates the relative amplitude of the current peak of hydrogen adsorption on (100) sites distributed on the one-dimensional surface domains to that on the two-dimensional surface domains. The in situ FTIR spectroscopic results demonstrated that the reduction of CO2 on the Pt(100) dominated by two-dimensional surface domains produced only bridge-bonded CO (COB) species, which give rise to IR absorption near 1840 cm(-1). However both bridge- and linear-bonded CO (COL, yielding IR absorption at around 2010 cm(-1)) species are found for CO2 reduction on the Pt(100) dominated by one-dimensional surface domains. The small intensity of the COL and COB bands indicates that coverage by reduced CO2 species (r-CO2. or COL and COB species) is low. The cyclic voltammetric (CV) studies confirmed quantitatively the in situ FTIRS results, and revealed that the r-CO2 species adsorb preferentially on (100) sites distributed on the two-dimensional surface domains. The initial rate of CO2 reduction upsilon (i), i.e., the rate of CO2 reduction on a clean Pt(100) surface, has been determined quantitatively from studies using a programmed potential step technique. It has been demonstrated that the maximum values of upsilon (i)(upsilon (m)(i)) measured on Pt(100) electrodes with different surface structures all appeared at -0.19 V. From analysis of the relationship between upsilon (m)(i) and gamma we have determined that the upsilon (m)(i) of CO2 reduction on (100) sites distributed on the two-dimensional surface domains is 0.53 x 10(-11) mol cm(-2) s(-1) and that on (100) sites distributed on the one-dimensional surface domains is approximately 2.66 x 10(-11) Mol cm(-2) s(-1). Based on in situ FTIRS and electrochemical studies a migration process of the r-CO2 from the one-dimensional surface domains to the two-dimensional surface domains has been proposed to be involved in CO2 reduction. The present study has thrown new light on the electrocatalytic activity of different surface structures of a Pt(100) electrode and the surface processes and kinetics of CO2 reduction

Soliton superlattices in twisted hexagonal boron nitride.

Properties of atomic van der Waals heterostructures are profoundly influenced by interlayer coupling, which critically depends on stacking of the proximal layers. Rotational misalignment or lattice mismatch of the layers gives rise to a periodic modulation of the stacking, the moiré superlattice. Provided the superlattice period extends over many unit cells, the coupled layers undergo lattice relaxation, leading to the concentration of strain at line defects - solitons - separating large area commensurate domains. We visualize such long-range periodic superstructures in thin crystals of hexagonal boron nitride using atomic-force microscopy and nano-infrared spectroscopy. The solitons form sub-surface hexagonal networks with periods of a few hundred nanometers. We analyze the topography and infrared contrast of these networks to obtain spatial distribution of local strain and its effect on the infrared-active phonons of hBN

SUMO-2 promotes mRNA translation by enhancing interaction between eIF4E and eIF4G

Small ubiquitin-like modifier (SUMO) proteins regulate many important eukaryotic cellular processes through reversible covalent conjugation to target proteins. In addition to its many well-known biological consequences, like subcellular translocation of protein, subnuclear structure formation, and modulation of transcriptional activity, we show here that SUMO-2 also plays a role in mRNA translation. SUMO-2 promoted formation of the active eukaryotic initiation factor 4F (eIF4F) complex by enhancing interaction between Eukaryotic Initiation Factor 4E (eIF4E) and Eukaryotic Initiation Factor 4G (eIF4G), and induced translation of a subset of proteins, such as cyclinD1 and c-myc, which essential for cell proliferation and apoptosis. As expected, overexpression of SUMO-2 can partially cancel out the disrupting effect of 4EGI-1, a small molecule inhibitor of eIF4E/eIF4G interaction, on formation of the eIF4F complex, translation of the cap-dependent protein, cell proliferation and apoptosis. On the other hand, SUMO-2 knockdown via shRNA partially impaired cap-dependent translation and cell proliferation and promoted apoptosis. These results collectively suggest that SUMO-2 conjugation plays a crucial regulatory role in protein synthesis. Thus, this report might contribute to the basic understanding of mammalian protein translation and sheds some new light on the role of SUMO in this process. © 2014 Chen et al

Down-regulated CK8 expression in human intervertebral disc degeneration

As an intermediate filament protein, cytokeratin 8 (CK8) exerts multiple cellular functions. Moreover, it has been identified as a marker of notochord cells, which play essential roles in human nucleus pulposus (NP). However, the distribution of CK8 positive cells in human NP and their relationship with intervertebral disc degeneration (IDD) have not been clarified until now. Here, we found the percentage of CK8 positive cells in IDD (25.7+/-4.14%) was significantly lower than that in normal and scoliosis NP (51.9+/-9.73% and 47.8+/-5.51%, respectively, p<0.05). Western blotting and qRT-PCR results confirmed the down-regulation of CK8 expression in IDD on both of protein and mRNA levels. Furthermore, approximately 37.4% of cell clusters were CK8 positive in IDD. Taken together, this is the first study to show a down-regulated CK8 expression and the percentage of CK8 positive cell clusters in IDD based upon multiple lines of evidence. Consequently, CK8 positive cells might be considered as a potential option in the development of cellular treatment strategies for NP repair.published_or_final_versio

Changing planar thin film growth into self-assembled island formation by adjusting experimental conditions

Illustrated in this paper are two examples of altering planar growth into self-assembled island formation by adapting experimental conditions. Partial oxidation, undersaturated solution and high temperature change Frank-Van der Merwe (FM) growth of Al0.3Ga0.7As in liquid phase epitaxy (LPE) into isolated island deposition. Low growth speed, high temperature and in situ annealing in molecular beam epitaxy (MBE) cause the origination of InAs/GaAs quantum dots (QDs) to happen while the film is still below critical thickness in Stranski-Krastanow (SK) mode. Sample morphologies are characterized by scanning electron microscopy (SEM) or atomic force microscopy (AFM). It is suggested that such achievements are of value not only to fundamental researches but also to spheres of device applications as well. (c) 2004 Elsevier B.V. All rights reserved

Construction of cytoplasmic molecular markers distinguishing Danio rerio from Gobiocypris rarus at high identity domains based on MP-PCR strategy and Sybr Green I detection

To distinguish the cytoplasm of Danio rerio from that of Gobiocypris rarus, we cloned G. rarus COXI and constructed cytoplasmic molecular markers at the high identity domains of COXI by mutated primer PCR (MP-PCR for short). Then Sybr Green I was used to detect the single amplicon. As a result, we succeeded in getting the cytoplasmic molecular markers, G.M COXI and Z.M COXI, by MP-PCR strategy. They were used to detect the sperm-derived mtDNA in the sexual hybrid embryos (D. rerio female x G. rarus male) before the sphere stage. In the present study, all results demonstrate that MP-PCR approach and Sybr Green I detection are feasible to construct the molecular markers to identify genes that shared high identity.To distinguish the cytoplasm of Danio rerio from that of Gobiocypris rarus, we cloned G. rarus COXI and constructed cytoplasmic molecular markers at the high identity domains of COXI by mutated primer PCR (MP-PCR for short). Then Sybr Green I was used to detect the single amplicon. As a result, we succeeded in getting the cytoplasmic molecular markers, G.M COXI and Z.M COXI, by MP-PCR strategy. They were used to detect the sperm-derived mtDNA in the sexual hybrid embryos (D. rerio female x G. rarus male) before the sphere stage. In the present study, all results demonstrate that MP-PCR approach and Sybr Green I detection are feasible to construct the molecular markers to identify genes that shared high identity