627 research outputs found

    Adubação verde no crescimento e na produção de Schinus terebinthifolius, Hibiscus sabdariffa e Jacaranda decurrens.

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    bitstream/item/68608/1/005-moreira-adubacao.pdfPublicado também no Cadernos de Agroecologia, v. 7, n.2, 2012

    Compostos fenĂłlicos de Hibiscus sabdariffa e influĂȘncia de resĂ­duos orgĂąnicos em sua propriedade antitumoral e antioxidante

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    The aim of this study was to evaluate the phenolic and flavonoids contents and the antioxidant and antitumoral activity of leaf and calyx methanolic extracts from Hibiscus sabdariffa (roselle) cultivated with poultry litter and organosuper (R) under three modes of application. The total phenolic content in the each extract was determined using the Folin-Ciocalteu reagent and for aluminium chloride flavonoids. The antioxidant parameters were analyzed using a 2, 2-diphenyl-1-picrylhydrazyl ( DPPH.) free radical scavenging assay. An antitumor colorimetric assay using sulforhodamine B. The highest contents of phenolic and flavonoids were observed in leaf extracts (389.98 and 104.52 mg g(-1), respectively) and calyx extracts (474.09 and 148.35 mg g(-1), respectively) from plants cultivated with organosuper., although these values did not differ significantly from those observed for the other treatments. The average IC50 of leaves (43.48 mu g mL(-1)) and calyces (37.15 mu g mL(-1)) demonstrated that both have substances that may contribute to free radical scavenging action. The methanol extract from calyces showed significant selective activity against a leukemia line (K-562), with IC50 values of 0.12 mg mL(-1) (organosuper (R)) and 1.16 mg mL(-1) (poultry litter), with concentration-dependent, cytotoxic and cytocidal effects7516976CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQFUNDAÇÃO DE APOIO AO DESENVOLVIMENTO DO ENSINO, CIÊNCIA E TECNOLOGIA DO ESTADO DE MATO GROSSO DO SUL - FUNDECTO objetivo deste estudo foi avaliar a atividade antioxidante, antitumoral e o conteĂșdo de fenĂłlicos e flavonoides do extrato metanĂłlico das folhas e cĂĄlices de Hibiscus sabdariffa (rosela) cultivada com cama de frango e organosuper Âź em trĂȘs modos de aplicação. O conteĂșdo fenĂłlico total de cada extrato foi determinado utilizando o reagente de Folin-Ciocalteu e cloreto de alumĂ­nio para flavonoides. Os parĂąmetros antioxidantes foram avaliados pelo ensaio de seqĂŒestro de radical livre 2, 2-difenil-1-picrilhidrazil (DPPH.). Na avaliação antitumoral utilizou-se o ensaio colorimĂ©trico com sulforrodamina B. Observou-se o maior conteĂșdo de fenĂłlicos e flavonoides em extratos de folhas (389.98 e 104.52 mg g–1, respectivamente) e extratos de cĂĄlice (474.09 e 148.35 mg g–1, respectivamente) de plantas cultivadas com organosuper Âź, embora esses valores nĂŁo diferiram significativamente daqueles observados para os outros tratamentos. O IC50 de folhas (43.48 ”g mL–1) e cĂĄlices (37.15 ”g mL–1) demonstrou que ambos tĂȘm substĂąncias que podem contribuir para a ação seqĂŒestradora de radicais livres. O extrato metanĂłlico dos cĂĄlices mostrou seletividade na linhagem de leucemia (K-562), com valores de IC50 de 0,12 mg mL–1 (organosuperÂź) e 1,16 mg mL–1 (cama-de-frango) com concentração-dependente e efeito citotĂłxico e citocidaUFD

    Boltzmann equation and hydrodynamic fluctuations

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    We apply the method of invariant manifolds to derive equations of generalized hydrodynamics from the linearized Boltzmann equation and determine exact transport coefficients, obeying Green-Kubo formulas. Numerical calculations are performed in the special case of Maxwell molecules. We investigate, through the comparison with experimental data and former approaches, the spectrum of density fluctuations and address the regime of finite Knudsen numbers and finite frequencies hydrodynamics.Comment: This is a more detailed version of a related paper: I.V. Karlin, M. Colangeli, M. Kroger, PRL 100 (2008) 214503, arXiv:0801.2932. It contains comparison between predictions and experiment, in particular. 11 pages, 6 figures, 2 table

    The Phononic Casimir Effect: An Analog Model

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    We discuss the quantization of sound waves in a fluid with a linear dispersion relation and calculate the quantum density fluctuations of the fluid in several cases. These include a fluid in its ground state. In this case, we discuss the scattering cross section of light by the density fluctuations, and find that in many situations it is small compared to the thermal fluctuations, but not negligibly small and might be observable at room temperature. We also consider a fluid in a squeezed state of phonons and fluids containing boundaries. We suggest that the latter may be a useful analog model for better understanding boundary effects in quantum field theory. In all cases involving boundaries which we consider, the mean squared density fluctuations are reduced by the presence of the boundary. This implies a reduction in the light scattering cross section, which is potentially an observable effect.Comment: 8 pages, 1 figure, talk presented at "60 Years of Casimir Effect", Brasilia, Brazil, June 200

    IGHMBP2 mutation associated with organ-specific autonomic dysfunction

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    Biallelic mutations in the IGHMBP2 have been associated with two distinct phenotypes: spinal muscular atrophy with respiratory distress type 1 (SMARD1) and CMT2S. We describe a patient who developed progressive muscle weakness and wasting in her upper and lower limbs from infancy. She developed respiratory involvement at age 9, eventually requiring 24-h non-invasive ventilation, and severe autonomic dysfunction restricted to the gastrointestinal tract. Neurophysiological studies at age 27 years revealed absent sensory and motor responses and severe chronic denervation changes in proximal muscles of the upper limbs. Targeted multigene panel sequencing detected a novel homozygous missense variant in the IGHMBP2 gene (c.1325A > G; p.Tyr442Cys). This variant was validated by Sanger sequencing and co-segregation analysis confirmed that both parents were asymptomatic heterozygous carriers. This case report confirms that IGHMBP2 related disorders can result in a severe peripheral neuropathy with gastrointestinal autonomic dysfunction requiring parenteral nutrition

    Evidence for self-similar bedload transport on Andean alluvial fans, Iglesia basin, south Central Argentina

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    Self‐similar downstream grain‐size fining trends in fluvial deposits are being increasingly used to simplify equilibrium sediment transport dynamics in numerical models. Their ability to collapse time‐averaged behavior of a depositional system into a simple mass balance framework makes them ideal for exploring the sensitivity of sediment routing systems to their climatic and tectonic boundary conditions. This is important if we want to better understand the sensitivity of landscapes to environmental change over timescales >102 years. However, the extent to which self‐similarity is detectable in the deposits of natural rivers is not fully constrained. In transport‐limited rivers, stored sediment can be remobilized or “recycled” and this behavior has been highlighted as a mechanism by which externally forced grain‐size fining trends are distorted. Here we evaluate evidence of self‐similarity in surface gravel‐size distributions on three geomorphically diverse alluvial fans in the Iglesia basin, south Central Argentine Andes. We find that size distributions are self‐similar, deviating from that condition only when significant variability occurs in the coarse tails of the distributions. Our analysis indicates a strong correlation between the degree of sediment recycling and the proportion of coarse clasts present on the bed surface. However, by fitting a relative mobility transfer function, we demonstrate that size‐selectivity alone can explain the bulk size distributions observed. This strengthens the application of self‐similar grain size fining models to solving problems of mass balance in a range of geomorphic settings, with an aim for reconstructing environmental boundary conditions from stratigraphy

    Will opposites attract? Similarities and differences in students' perceptions of the stereotype profiles of other health and social care professional groups

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    The extent to which health and social care (HSC) students hold stereotypical views of other HSC professional groups is of great potential importance to team working in health care. This paper explores students' perceptions of different HSC professional groups at the beginning of their university programmes. Findings are presented from an analysis of baseline data collected as part of the New Generation Project longitudinal cohort study which is assessing the impact of interprofessional education over time on a range of variables including stereotyping. Questionnaires were administered to a cohort of over 1200 students from 10 different HSC professional groups entering their first year of university. Stereotypes were measured using a tool adapted from Barnes et al. (2000) designed to elicit stereotype ratings on a range of nine characteristics. The findings confirm that students arrive at university with an established and consistent set of stereotypes about other health and social care professional groups. Stereotypical profiles were compiled for each professional group indicating the distinctive characteristics of the groups as well as the similarities and differences between groups. Midwives, social workers and nurses were rated most highly on interpersonal skills and on being a team player whilst doctors were rated most highly on academic ability. Doctors, midwives and social workers were perceived as having the strongest leadership role, whilst doctors were also rated most highly on decision making. All professions were rated highly on confidence and professional competence and, with the exception of social workers, on practical skills. A comparison of profiles for each professional group reveals that, for example, pharmacists and doctors were perceived as having very similar characteristics as were social workers, midwives and nurses. However, the profiles of nurses and doctors were perceived to be very different. The implications of these similarities and differences are discussed in terms of their potential impact on interprofessional interactions, role boundaries and team working

    Microsatellite primers for two threatened orchids in Florida: Encyclia tampensis and Cyrtopodium punctatum (Orchidaceae)1

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    Premise of the study: The Million Orchid Project at Fairchild Tropical Botanic Garden is an initiative to propagate native orchids for reintroduction into Miami?s urban landscapes. The aim of this study was to develop microsatellites for Encyclia tampensis and Cyrtopodium punctatum (Orchidaceae). Methods and Results: Ten microsatellites were developed for each species. For E. tampensis sampled from the natural population, allele numbers ranged from one to four, with an average observed heterozygosity (Ho) of 0.314 and average expected heterozygosity (He) of 0.281. For the individuals from cultivation, allele numbers ranged from one to six, with an average Ho of 0.35 and an average He of 0.224. For C. punctatum, allele numbers ranged from one to three, with an average Ho of 0.257 and an average He of 0.272. Conclusions: These microsatellites will be used to assess the genetic diversity of natural and cultivated populations with the intention of guiding genetic breeding under the Million Orchid Project

    Abnormality in glutamine-glutamate cycle in the cerebrospinal fluid of cognitively intact elderly individuals with major depressive disorder: a 3-year follow-up study

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    Major depressive disorder (MDD), common in the elderly, is a risk factor for dementia. Abnormalities in glutamatergic neurotransmission via the N-methyl-D-aspartate receptor (NMDA-R) have a key role in the pathophysiology of depression. This study examined whether depression was associated with cerebrospinal fluid (CSF) levels of NMDA-R neurotransmission-associated amino acids in cognitively intact elderly individuals with MDD and age- and gender-matched healthy controls. CSF was obtained from 47 volunteers (MDD group, N = 28; age- and gender-matched comparison group, N = 19) at baseline and 3-year follow-up (MDD group, N = 19; comparison group, N = 17). CSF levels of glutamine, glutamate, glycine, L-serine and D-serine were measured by highperformance liquid chromatography. CSF levels of amino acids did not differ across MDD and comparison groups. However, the ratio of glutamine to glutamate was significantly higher at baseline in subjects with MDD than in controls. The ratio decreased in individuals with MDD over the 3-year follow-up, and this decrease correlated with a decrease in the severity of depression. No correlations between absolute amino-acid levels and clinical variables were observed, nor were correlations between amino acids and other biomarkers (for example, amyloid-ÎČ42, amyloid-ÎČ40, and total and phosphorylated tau protein) detected. These results suggest that abnormalities in the glutamine–glutamate cycle in the communication between glia and neurons may have a role in the pathophysiology of depression in the elderly. Furthermore, the glutamine/glutamate ratio in CSF may be a state biomarker for depression
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