3,057 research outputs found

    In situ imaging of field emission from individual carbon nanotubes and their structural damage

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    ©2002 American Institute of Physics. The electronic version of this article is the complete one and can be found online at: http://link.aip.org/link/?APPLAB/80/856/1DOI:10.1063/1.1446994Field emission of individual carbon nanotubes was observed by in situ transmission electron microscopy. A fluctuation in emission current was due to a variation in distance between the nanotube tip and the counter electrode owing to a "head-shaking" effect of the nanotube during field emission. Strong field-induced structural damage of a nanotube occurs in two ways: a piece-by-piece and segment-by-segment pilling process of the graphitic layers, and a concentrical layer-by-layer stripping process. The former is believed owing to a strong electrostatic force, and the latter is likely due to heating produced by emission current that flowed through the most outer graphitic layers

    Photonic Clusters

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    We show through rigorous calculations that dielectric microspheres can be organized by an incident electromagnetic plane wave into stable cluster configurations, which we call photonic molecules. The long-range optical binding force arises from multiple scattering between the spheres. A photonic molecule can exhibit a multiplicity of distinct geometries, including quasicrystal-like configurations, with exotic dynamics. Linear stability analysis and dynamical simulations show that the equilibrium configurations can correspond with either stable or a type of quasi-stable states exhibiting periodic particle motion in the presence of frictional dissipation.Comment: 4 pages, 3 figure

    Alterations in the processing of non-drug-related affective stimuli in abstinent heroin addicts.

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    Long-term exposure to drug may alter the neural system associated with affective processing, as evidenced by both clinical observations and behavioral data documenting dysfunctions in emotional experiences and processing in drug addicts. Although many imaging studies examined neural responses to drug or drug-related cues in addicts, there have been few studies explicitly designed to reveal their neural abnormalities in processing non-drug-related natural affective materials. The present study asked abstinent heroin addicts and normal controls to passively view standardized affective pictures of positive, negative, or neutral valence and compared their brain activities with functional MRI. Compared to normal controls, addicts showed reduced activation in right amygdala in response to the affective pictures, consistent with previous reports of blunted subjective experience for affective stimuli in addicts. Furthermore, in two visual cortical areas BA 19 and 37, while the controls showed greater responses to positive pictures than to negative ones replicating literature findings, the addicts showed the opposite pattern. The results reveal a complex pattern of altered processing of non-drug-related affective materials in addicts showing both heightened and blunted neural responses in different brain regions and for different stimulus valence. The present study highlights the importance of brain imaging research on drug addicts' processing of affective stimuli in understanding disruptions in their emotion circuitry

    Effects of dimers on cooperation in the spatial prisoner's dilemma game

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    We investigate the evolutionary prisoner's dilemma game in structured populations by introducing dimers, which are defined as that two players in each dimer always hold a same strategy. We find that influences of dimers on cooperation depend on the type of dimers and the population structure. For those dimers in which players interact with each other, the cooperation level increases with the number of dimers though the cooperation improvement level depends on the type of network structures. On the other hand, the dimers, in which there are not mutual interactions, will not do any good to the cooperation level in a single community, but interestingly, will improve the cooperation level in a population with two communities. We explore the relationship between dimers and self-interactions and find that the effects of dimers are similar to that of self-interactions. Also, we find that the dimers, which are established over two communities in a multi-community network, act as one type of interaction through which information between communities is communicated by the requirement that two players in a dimer hold a same strategy.Comment: 12 pages and 3 figure

    Metropolis simulations of Met-Enkephalin with solvent-accessible area parameterizations

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    We investigate the solvent-accessible area method by means of Metropolis simulations of the brain peptide Met-Enkephalin at 300K K. For the energy function ECEPP/2 nine atomic solvation parameter (ASP) sets are studied. The simulations are compared with one another, with simulations with a distance dependent electrostatic permittivity ϵ(r)\epsilon (r), and with vacuum simulations (ϵ=2\epsilon =2). Parallel tempering and the biased Metropolis techniques RM1_1 are employed and their performance is evaluated. The measured observables include energy and dihedral probability densities (pds), integrated autocorrelation times, and acceptance rates. Two of the ASP sets turn out to be unsuitable for these simulations. For all other systems selected configurations are minimized in search of the global energy minima, which are found for the vacuum and the ϵ(r)\epsilon(r) system, but for none of the ASP models. Other observables show a remarkable dependence on the ASPs. In particular, we find three ASP sets for which the autocorrelations at 300 K are considerably smaller than for vacuum simulations.Comment: 10 pages and 8 figure

    c-Jun NH2-terminal kinase-dependent upregulation of DR5 mediates cooperative induction of apoptosis by perifosine and TRAIL

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    <p>Abstract</p> <p>Background</p> <p>Perifosine, an alkylphospholipid tested in phase II clinical trials, modulates the extrinsic apoptotic pathway and cooperates with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to augment apoptosis. The current study focuses on revealing the mechanisms by which perifosine enhances TRAIL-induced apoptosis.</p> <p>Results</p> <p>The combination of perifosine and TRAIL was more active than each single agent alone in inducing apoptosis of head and neck squamous cell carcinoma cells and inhibiting the growth of xenografts. Interestingly, perifosine primarily increased cell surface levels of DR5 although it elevated the expression of both DR4 and DR5. Blockade of DR5, but not DR4 upregulation, via small interfering RNA (siRNA) inhibited perifosine/TRAIL-induced apoptosis. Perifosine increased phosphorylated c-Jun NH<sub>2</sub>-terminal kinase (JNK) and c-Jun levels, which were paralleled with DR4 and DR5 induction. However, only DR5 upregulaiton induced by perifosine could be abrogated by both the JNK inhibitor SP600125 and JNK siRNA. The antioxidants, N-acetylcysteine and glutathione, but not vitamin C or tiron, inhibited perifosine-induced elevation of p-c-Jun, DR4 and DR5. Moreover, no increased production of reactive oxygen species was detected in perifosine-treated cells although reduced levels of intracellular GSH were measured.</p> <p>Conclusions</p> <p>DR5 induction plays a critical role in mediating perifosine/TRAIL-induced apoptosis. Perifosine induces DR5 expression through a JNK-dependent mechanism independent of reactive oxygen species.</p

    Theoretic specific heat from spin wave in comparison with experimental results in Fe-oxide superconductors

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    Low temperature electrical measurements of the resistivity, the Hall effect and the magnetoconductivity were performed on an InGaN sample having an electron concentration far above the critical value for the metalinsulator transition. Weak localization effect and two-band model were used to analyze the magnetoconductivity data. The temperature dependence of the inelastic scattering time was extracted from the magnetoconductivity data at low temperatures. It was found that the inelastic scattering time is proportional to T⁻¹.⁶³, suggesting that electron–electron interactions are dominant

    The NLO QCD Corrections to BcB_c Meson Production in Z0Z^0 Decays

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    The decay width of Z0Z^0 to BcB_c meson is evaluated at the next-to-leading order(NLO) accuracy in strong interaction. Numerical calculation shows that the NLO correction to this process is remarkable. The quantum chromodynamics(QCD)renormalization scale dependence of the results is obviously depressed, and hence the uncertainties lying in the leading order calculation are reduced.Comment: 14 pages, 7 figures; references added; expressions and typos ammende

    Observation of Ds+pnˉD^+_s\rightarrow p\bar{n} and confirmation of its large branching fraction

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    The baryonic decay Ds+pnˉD^+_s\rightarrow p\bar{n} is observed, and the corresponding branching fraction is measured to be (1.21±0.10±0.05)×103(1.21\pm0.10\pm0.05)\times10^{-3}, where the first uncertainty is statistical and second systematic. The data sample used in this analysis was collected with the BESIII detector operating at the BEPCII e+ee^+e^- double-ring collider with a center-of-mass energy of 4.178~GeV and an integrated luminosity of 3.19~fb1^{-1}. The result confirms the previous measurement by the CLEO Collaboration and is of greatly improved precision, which may deepen our understanding of the dynamical enhancement of the W-annihilation topology in the charmed meson decays
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