Joint Deployment and Resource Management for VLC-enabled RISs-assisted UAV Networks

In this paper, the problem of the deployment and resource management for visible light communication (VLC)-enabled, reconfigurable intelligent surfaces (RISs)-assisted unmanned aerial vehicle (UAV) networks is investigated. In the considered model, UAVs provide terrestrial users with wireless services and illumination simultaneously. Moreover, RISs are utilized to further improve the channel quality between UAVs and users. This joint placement and resource management problem is constructed aiming at acquiring the optimal UAV deployment, RISs phase shift, user and RIS association that satisfies the users’ needs with minimum consumption of the UAVs’ energy. An iterative algorithm that alternately optimizes continuous and binary variables is proposed to solve this mixed-integer programming problem. Specifically, RISs phase shift optimization is solved by phases alignment method and semidefinite program algorithm. Next, the successive convex approximation algorithm is proposed to settle the UAV deployment problem. The user and RIS association variables are relaxed to the continuous ones before adopting the dual method to find the optimal solution. Moreover, a greedy algorithm is proposed as an alternative to RIS association optimization with low complexity. Simulation results show that the proposed two schemes harvest the superior performance of 34.85% and 32.11% energy consumption reduction over the case without RIS, respectively

Precise determination of stellar parameters of the ZZ Ceti and DAZ white dwarf GD 133 through asteroseismology

An increasing number of white dwarf stars show atmospheric chemical composition polluted by heavy elements accreted from debris disk material. The existence of such debris disks strongly suggests the presence of one or more planet(s) whose gravitational interaction with rocky planetesimals is responsible for their disruption by tidal effect. The ZZ Ceti pulsator and polluted DAZ white dwarf GD 133 is a good candidate for searching for such a potential planet. We started in 2011 a photometric follow-up of its pulsations. As a result of this work in progress, we used the data gathered from 2011 to 2015 to make an asteroseismological analysis of GD 133, providing the star parameters from a best fit model with $M$/$M_{\odot}$ = 0.630 $\pm$ 0.002, $T_{\rm eff}$ = 12400 K $\pm$ 70 K, log($M_{\rm He}/M$) = -2.00 $\pm$ 0.02, log($M_{\rm H}/M$) = -4.50 $\pm$ 0.02 and determining a rotation period of $\approx$ 7 days.Comment: 10 pages, 13 figures, accepted by MNRA

The Subleading Term of the Strong Coupling Expansion of the Heavy-Quark Potential in a N=4\mathcal N=4 Super Yang-Mills Vacuum

Applying the AdS/CFT correspondence, the expansion of the heavy-quark potential of the ${\cal N}=4$ supersymmetric Yang-Mills theory at large $N_c$ is carried out to the sub-leading term in the large 't Hooft coupling at zero temperature. The strong coupling corresponds to the semi-classical expansion of the string-sigma model, the gravity dual of the Wilson loop operator, with the sub-leading term expressed in terms of functional determinants of fluctuations. The singularities of these determinants are examined and their contributions are evaluated numerically.Comment: Updated version with minor typo corrections and new reference

Charged lepton electric dipole moments with the localized leptons and the new Higgs doublet in the two Higgs doublet model

We study the lepton electric dipole moments in the split fermion scenario, in the two Higgs doublet model, where the new Higgs scalars are localized around the origin in the extra dimension, with the help of the localizer field. We observe that the numerical value of the electron (muon, tau) electric dipole moment is at the order of the magnitude of 10^{-31} (10^{-24}, 10^{-22}) (e-cm) and this quantity is sensitive the new Higgs localization in the extra dimension.Comment: 20 pages, 7 figure

Reprogramming of Sheep Fibroblasts into Pluripotency under a Drug-Inducible Expression of Mouse-Derived Defined Factors

Animal embryonic stem cells (ESCs) provide powerful tool for studies of early embryonic development, gene targeting, cloning, and regenerative medicine. However, the majority of attempts to establish ESC lines from large animals, especially ungulate mammals have failed. Recently, another type of pluripotent stem cells, known as induced pluripotent stem cells (iPSCs), have been successfully generated from mouse, human, monkey, rat and pig. In this study we show sheep fibroblasts can be reprogrammed to pluripotency by defined factors using a drug-inducible system. Sheep iPSCs derived in this fashion have a normal karyotype, exhibit morphological features similar to those of human ESCs and express AP, Oct4, Sox2, Nanog and the cell surface marker SSEA-4. Pluripotency of these cells was further confirmed by embryoid body (EB) and teratoma formation assays which generated derivatives of all three germ layers. Our results also show that the substitution of knockout serum replacement (KSR) with fetal bovine serum in culture improves the reprogramming efficiency of sheep iPSCs. Generation of sheep iPSCs places sheep on the front lines of large animal preclinical trials and experiments involving modification of animal genomes

Computer-Based Screening of Functional Conformers of Proteins

A long-standing goal in biology is to establish the link between function, structure, and dynamics of proteins. Considering that protein function at the molecular level is understood by the ability of proteins to bind to other molecules, the limited structural data of proteins in association with other bio-molecules represents a major hurdle to understanding protein function at the structural level. Recent reports show that protein function can be linked to protein structure and dynamics through network centrality analysis, suggesting that the structures of proteins bound to natural ligands may be inferred computationally. In the present work, a new method is described to discriminate protein conformations relevant to the specific recognition of a ligand. The method relies on a scoring system that matches critical residues with central residues in different structures of a given protein. Central residues are the most traversed residues with the same frequency in networks derived from protein structures. We tested our method in a set of 24 different proteins and more than 260,000 structures of these in the absence of a ligand or bound to it. To illustrate the usefulness of our method in the study of the structure/dynamics/function relationship of proteins, we analyzed mutants of the yeast TATA-binding protein with impaired DNA binding. Our results indicate that critical residues for an interaction are preferentially found as central residues of protein structures in complex with a ligand. Thus, our scoring system effectively distinguishes protein conformations relevant to the function of interest

Regulation of Spike Timing-Dependent Plasticity of Olfactory Inputs in Mitral Cells in the Rat Olfactory Bulb

The recent history of activity input onto granule cells (GCs) in the main olfactory bulb can affect the strength of lateral inhibition, which functions to generate contrast enhancement. However, at the plasticity level, it is unknown whether and how the prior modification of lateral inhibition modulates the subsequent induction of long-lasting changes of the excitatory olfactory nerve (ON) inputs to mitral cells (MCs). Here we found that the repetitive stimulation of two distinct excitatory inputs to the GCs induced a persistent modification of lateral inhibition in MCs in opposing directions. This bidirectional modification of inhibitory inputs differentially regulated the subsequent synaptic plasticity of the excitatory ON inputs to the MCs, which was induced by the repetitive pairing of excitatory postsynaptic potentials (EPSPs) with postsynaptic bursts. The regulation of spike timing-dependent plasticity (STDP) was achieved by the regulation of the inter-spike-interval (ISI) of the postsynaptic bursts. This novel form of inhibition-dependent regulation of plasticity may contribute to the encoding or processing of olfactory information in the olfactory bulb