73 research outputs found
Certify or not? An analysis of organic food supply chain with competing suppliers
Customers expect companies to provide clear health-related information for the products they purchase in a big data environment. Organic food is data-enabled with the organic label, but the certification cost discourages small-scale suppliers from certifying their product. This lack of a label means that product that satisfies the organic standard is regarded as conventional product. By considering the trade-off between the profit gained from organic label and additional costs of certification, this paper investigates an organic food supply chain where a leading retailer procures from two suppliers with different brands. Customers care about both the brand-value and quality (more specifically, if food is organic or not) when purchasing the product. We explore the organic certification and wholesale pricing strategies for suppliers, and the supplier selection and retail pricing strategies for the retailer. We find that when two suppliers adopt asymmetric certification strategy, the retailer tends to procure the product with organic label. The supplier without a brand name can compensate with organic certification, which leads to more profits than the branded rival. As the risk of being abandoned by the retailer increases, the supplier without a brand name is more eager than the rival to obtain the organic label. If both suppliers certify the product, however, they will fall into a prisonerâs dilemma under situation with low health utility from organic label and high certification cost
Neurodevelopmental disorder with microcephaly, ataxia, and seizures syndrome: expansion of the clinical spectrum
Neurodevelopmental disorder with microcephaly, ataxia, and seizures (NEDMAS) syndrome is a rare neurodevelopmental disorder characterized by moderate intellectual disability (ID), thin body habitus, microcephaly, seizures, ataxia, muscle weakness, and speech impairment. So far, only two families with NEDMAS have been reported. We report the clinical and molecular characteristics of three unrelated Turkish families with four NEDMAS patients. Whole-exome sequencing was used to search for the disease-causing variant. The main manifestations of the probands are severe developmental delay and ID, thin body habitus, and severe hypotonia. Brain imaging revealed bilateral cerebral and cerebellar diffuse atrophy. Sequencing results showed that both patients carried a novel missense variant c.1196C>T (p.Thr399Met) in the seryl-tRNA synthetase gene. Our findings help expand the variant spectrum of NEDMAS and provide additional information for diagnosing cases with atypical features. © 2022 Lippincott Williams and Wilkins. All rights reserved
Ăankırı yöresinde koyun ve keçilerde Toxaplasma gondii seropozitifliÄinin Sabin-Feldman boya testi ile saptanması.
ĂversvĂ€mningar Ă€r ett stort globalt problem som förvĂ€ntas bli allt mer frekventa. Syftet med denna studie Ă€r att utreda hur klimatanpassningsarbetet kring översvĂ€mningsrisker hanteras pĂ„ lokal nivĂ„, i detta fall i Halmstad kommun. Syftet menar ocksĂ„ att jĂ€mföra beskrivningen av hur arbetet bedrivs i praktiken med teori och tidigare forskning. FrĂ„gestĂ€llningarna som ska besvara syftet Ă€r om hur Halmstad kommun beskriver dess arbete och vad det finns för förklaring till detta samt hur detta kan tolkas och förklaras utifrĂ„n forskningsteoretiska begrepp âevidensâ och âurban resiliensâ.  Studien har utförts som en kvalitativ fallstudie genom en intervju med kommunal tjĂ€nsteperson och innehĂ„llsanalys av styrdokument relevanta för kommunens klimatanpassningsarbete. Det teoretiska ramverket bestĂ„r av begreppen âresiliensâ och âevidensâ som förklaras med en sammankopplad figur. Studiens resultat visar att klimatanpassningsarbetet Ă€r komplext dĂ„ flera aspekter mĂ„ste avvĂ€gas men Halmstad kommun Ă€r vĂ€lutvecklade inom frĂ„gan frĂ€mst dĂ„ de Ă€r en resursrik kommun. Flooding is a global issue thatâs becoming more frequent. This study means to investigate how climate adaptation may be managed on a local level, by performing a case study of Halmstad municipality. We mean to investigate and compare how the work is described in practice and theory. This will be done by answering questions on how the municipality describes their work, how it can be explained and how it can be interpreted in the context of the theoretical concepts' âevidenceâ and âurban resilienceâ. The study is based on qualitative methods, an interview and content analyses of strategic documents. The theory consists of the terms âresilienceâ and âevidenceâ that are interpreted with an explanatory figure.  The studies' result highlights the complexity of climate adaptation since many aspects of climate risk must be acknowledged. Halmstad can, however, be considered developed in this area which is explained by the resources at their disposal
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