609 research outputs found
Return times for Stochastic processes with power-law scaling
An analytical study of the return time distribution of extreme events for
stochastic processes with power-law correlation has been carried on. The
calculation is based on an epsilon-expansion in the correlation exponent:
C(t)=|t|^{-1+epsilon}. The fixed point of the theory is associated with
stretched exponential scaling of the distribution; analytical expressions,
valid in the pre-asymptotic regime, have been provided. Also the permanence
time distribution appears to be characterized by stretched exponential scaling.
The conditions for application of the theory to non-Gaussian processes have
been analyzed and the relations with the issue of return times in the case of
multifractal measures have been discussed.Comment: 9 pages, 5 figures, revtex
Single Shot Temporal Action Detection
Temporal action detection is a very important yet challenging problem, since
videos in real applications are usually long, untrimmed and contain multiple
action instances. This problem requires not only recognizing action categories
but also detecting start time and end time of each action instance. Many
state-of-the-art methods adopt the "detection by classification" framework:
first do proposal, and then classify proposals. The main drawback of this
framework is that the boundaries of action instance proposals have been fixed
during the classification step. To address this issue, we propose a novel
Single Shot Action Detector (SSAD) network based on 1D temporal convolutional
layers to skip the proposal generation step via directly detecting action
instances in untrimmed video. On pursuit of designing a particular SSAD network
that can work effectively for temporal action detection, we empirically search
for the best network architecture of SSAD due to lacking existing models that
can be directly adopted. Moreover, we investigate into input feature types and
fusion strategies to further improve detection accuracy. We conduct extensive
experiments on two challenging datasets: THUMOS 2014 and MEXaction2. When
setting Intersection-over-Union threshold to 0.5 during evaluation, SSAD
significantly outperforms other state-of-the-art systems by increasing mAP from
19.0% to 24.6% on THUMOS 2014 and from 7.4% to 11.0% on MEXaction2.Comment: ACM Multimedia 201
The effect of hydro-alcoholic extract of celery (Apium graveolens) leaves on serum level of testosterone, FSH and LH in male rats
Background and Objective: Celery (Apium graveolens) is a plant from Apiaceae family with high nutritional and medicinal use.This plant has many phytoestrogens that can affect the pituitary-gonadal axis. The purpose of this study was to investigate the effect of hydro-alcoholic extract of celery leaves on serum level of testosterone, FSH and LH in male rats. Materials and Methods: In this experimental study, thirty-two male wistar rats were randomly divided into four groups of eight rats each. The control group did not receive anything. The sham group received distilled water (as a solvent), and the experimental groups received doses of 200 and 300 mg/kg/ BW of hydro-alcoholic extract of celery leaves for 20 days. The extract was gavaged once a day. One day after the last gavage, the rats were anaesthetized and blood samples were collected from the heart and then serum levels of testosterone, LH and FSH were measured. The data were analyzed using SPSS software and ANOVA test. Results: Concentration of LH in the treatment group with doses of 200 mg/kg (0.39±0.02 mIU/dl) reduced in comparison with control (0.67±0.01 mIU/dl) and sham (0.73±0.02 mIU/dl) groups (P0.05). Conclusion: The results indicated that the administration of 200 mg/kg doses of celery extract causes a significant reduction in serum LH concentration, but it has no effect on ganadotropin and testosterone hormones in highest doses used in this study. This finding may be due to the presence of flavonoid and antioxidant proporties of celery
CFIm25 and alternative polyadenylation: Conflicting roles in cancer
Alternative polyadenylation (APA) is now widely recognized to regulate gene expression. APA is an RNA-processing mechanism that generates distinct 3� termini on mRNAs, producing mRNA isoforms. Different factors influence the initiation and development of this process. CFIm25 (among others) is a cleavage and polyadenylation factor that plays a key role in the regulation of APA. Shortening of the 3�UTRs on mRNAs leads to enhanced cellular proliferation and tumorigenicity. One reason may be the up-regulation of growth promoting factors, such as Cyclin D1. Different studies have reported a dual role of CFIm25 in cancer (both oncogenic and tumor suppressor). microRNAs (miRNAs) may be involved in CFIm25 function as well as competing endogenous RNAs (ceRNAs). The present review focuses on the role of CFIm25 in cancer, cancer treatment, and possible involvement in other human diseases. We highlight the involvement of miRNAs and ceRNAs in the function of CFIm25 to affect gene expression. The lack of understanding of the mechanisms and regulation of CFIm25 and APA has underscored the need for further research regarding their role in cancer and other diseases. © 201
Association of single nucleotide polymorphisms with renal cell carcinoma in Algerian population
Background: Renal cell carcinoma (RCC) is a common malignant tumor of the urinary system. The etiology of RCC is
a complex interaction between environmental and multigenetic factors. Genome-wide association studies have iden?
tifed new susceptibility risk loci for RCC. We examined associations of genetic variants of genes that are involved in
metabolism, DNA repair and oncogenes with renal cancer risk. A total of 14 single nucleotide polymorphisms (SNPs)
in 11 genes (VEGF, VHL, ATM, FAF1, LRRIQ4, RHOBTB2, OBFC1, DPF3, ALDH9A1 and EPAS1) were examined.
Methods: The current case?control study included 87 RCC patients and 114 controls matched for age, gender and
ethnic origin. The 14 tag-SNPs were genotyped by Sequenom MassARRAY? iPLEX using blood genomic DNA.
Results: Genotype CG and allele G of ATM rs1800057 were signifcantly associated with RCC susceptibility (p=0.043;
OR=8.47; CI=1.00?71.76). Meanwhile, we found that genotype AA of rs67311347 polymorphism could increase the
risk of RCC (p=0.03; OR=2.95; IC=1.10?7.89). While, genotype TT and T allele of ALDH9A1 rs3845536 were observed
to approach signifcance for a protective role against RCC (p=0.007; OR=0.26; CI=0.09?0.70).
Conclusion: Our results indicate that ATM rs1800057 may have an efect on the risk of RCC, and suggest that
ALDH9A1 was a protective factor against RCC in Algerian populatio
SSwWS: structural model of information architecture
The Web Technologies allow a representation of a domain of knowledge. This facilitates the conversion of an explicit and tacit knowledge to the possibility of adding knowledge to the Web for automatic processing by the computer. For this reason, it has been designed to be an architecture known as SSwWS (Search Semantic with Web Services) or Search Semantic Web Services, to show how to extend the functionality of the Web search and semantic raised by Berners-Lee, on the meta-references, defined in a Web ontology, so that a user on the Internet can find the answers to their questions through Web services in a simple and fast
The interaction of dark matter cusp with the baryon component in disk galaxies
In this paper we examine the effect of the formation and evolution of the
disk galaxy on the distribution of dark halo matter. We have made simulations
of isolated dark matter (DM) halo and two component (DM + baryons). N-body
technique was used for stellar and DM particles and TVD MUSCL scheme for
gas-dynamic simulations. The simulations include the processes of star
formation, stellar feedback, heating and cooling of the interstellar medium.
The results of numerical experiments with high spatial resolution let us to
conclude in two main findings. First, accounting of star formation and
supernova feedback resolves the so-called problem of cusp in distribution of
dark matter predicted by cosmological simulations. Second, the interaction of
dark matter with dynamic substructures of stellar and gaseous galactic disk
(e.g., spiral waves, bar) has an impact on the shape of the dark halo. In
particular, the in-plane distribution of dark matter is more symmetric in runs,
where the baryonic component was taken into account.Comment: 7 pages, 6 figure
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