82 research outputs found

    Osteoporosis due to testicular atrophy in male leprosy patients

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    A study was conducted to examine the relationship of testicular atrophy to bone metabolism in male leprosy patients. The study consisted of 31 leprosy patients (mean age: 62.0 years) and 31 healthy control men (mean age: 60.0 years). Measurements were made of their serum levels of free testosterone (FT), estradiol (E2), luteinizing hormone (LH) and 25-hydroxyvitamin D (25 OHD). Bone mineral density (BMD) was measured at radial sites and the lumbar vertebral bodies (L2-L4) by dual-energy X-ray absorptiometry using a Hologic QDR-2000 densitometer. FT and E2 levels were significantly lower and LH levels higher in leprosy patients than in controls. This represents a primary hypogonadal pattern. A value of 7.20pg/ml of FT (= Mean -1 SD of control) was used as a cut off value, and the subjects were subdivided into a hypogonadal group (HG) and a non hypogonadal group (non-HG). When the subjects were compared for differences in age, age at onset of disease, duration of disease, body mass index and BMD, only the duration of disease and BMD were significantly different between the two groups. Furthermore, BMD of the forearm significantly correlated with FT levels (r = 0.689, P &#60; 0.0001). Low BMD may be due to orchitis and testicular atrophy.</p

    地震時の飽和砂地盤の液状化現象のメカニズム

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    Many phenomena have been observed during the past large earthquakes that the liquefied saturated sandy layers give large damage to the various structures and the life lines. Hachinohe Institute of Technology(HIT)has succeeded to clarify the generation mechanism of liquefaction by the all-out investigations on the liquefaction appeared at the Hachinohe Port during the 1994 Far-OffSanriku Earthquake. Furthermore,the analyzing method developed in this study was applied to the severely liquefied sites in the 1948 Fukui,the 1969 Niigata and the 1983 Mid-Japan Sea Earthquakes. Consequently,the analyses can make the reasonable explanation for the phenomena at that time
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