ResViT: Residual vision transformers for multi-modal medical image synthesis

Multi-modal imaging is a key healthcare technology that is often underutilized due to costs associated with multiple separate scans. This limitation yields the need for synthesis of unacquired modalities from the subset of available modalities. In recent years, generative adversarial network (GAN) models with superior depiction of structural details have been established as state-of-the-art in numerous medical image synthesis tasks. GANs are characteristically based on convolutional neural network (CNN) backbones that perform local processing with compact filters. This inductive bias in turn compromises learning of contextual features. Here, we propose a novel generative adversarial approach for medical image synthesis, ResViT, to combine local precision of convolution operators with contextual sensitivity of vision transformers. ResViT employs a central bottleneck comprising novel aggregated residual transformer (ART) blocks that synergistically combine convolutional and transformer modules. Comprehensive demonstrations are performed for synthesizing missing sequences in multi-contrast MRI, and CT images from MRI. Our results indicate superiority of ResViT against competing methods in terms of qualitative observations and quantitative metrics

The protective effect of curcumin on the diabetic Rat Kidney: A stereological, electron microscopic and immunohistochemical study

The prevalence of diabetes in the world is increasing rapidly. Kidney diseases are among the most common medical disorders. The aim of this study was to investigate the effect of curcumin on the diabetic kidney. Thirty-five female Wistar albino rats were divided into seven groups. No procedure was performed on the Cont group. The Sham group received corn oil via gavage for 14 days. The curcumin (Curc) group received 30-mg/kg curcumin for 14 days, while the diabetes mellitus (DM) group received 50-mg/kg streptozotocin (STZ) in a single dose intraperitoneally. The DM + curcumin 1 (DC1) group received 30 mg/kg curcumin for 14 days, seven days after the application of STZ, while the DM + curcumin 2 (DC2) received 30 mg/kg curcumin for 14 days, 21 days after the application of STZ, and the DM + curcumin 3 (DC3) group received single-dose STZ at the same time as the application of 30 mg/kg curcumin for 14 days. Medulla, cortex, tubule, and glomerulus volume ratios were calculated using stereological techniques. Cortex volumes in the Sham and DM groups were significantly lower than in the Cont group (p < 0.05). The cortex volume in the DC3 group was also significantly lower than in the Curc group (p < 0.05). Medullary volume was significantly higher in the DC3 group compared to the DM group (p < 0.05). Curcumin was determined to exhibit a protective effect on the diabetic kidney since the glomerulus in the curcumin-exposed group exhibited a well-protected structure following experimentally induced diabetes based on light and electron microscopic analysis findings. These findings suggest that curcumin used following experimentally induced diabetes exhibits protective effects on the diabetic kidney

Hamit Fendoğlu'nun hayatı ve 1970-1980 yılları arasında Türk siyasetine etkisi

Ankara : İhsan Doğramacı Bilkent Üniversitesi İktisadi, İdari ve Sosyal Bilimler Fakültesi, Tarih Bölümü, 2016.This work is a student project of the The Department of History, Faculty of Economics, Administrative and Social Sciences, İhsan Doğramacı Bilkent University.by Pamuk, Fatih

Ruptured distal anterior choroidal artery aneurysm

WOS: 000262348500031PubMed ID: 19013815This report describes a patient with a rare distal anterior choroidal artery (AChoA) aneurysm that developed a right intracerebral haematoma and intraventricular haemorrhage and was treated by surgical exploration and clipping via a transtemporal/ventricular approach. The patient was discharged neurologically intact. We review the literature related to these rare aneurysms within the temporal horn, and the surgical anatomy of the AChoA. Crown Copyright (C) 2008 Published by Elsevier Ltd. All rights reserved

A child with primary Sjogren syndrome and a review of the literature

Primary Sjogren syndrome (pSS) is an uncommon disease in childhood. Childhood pSS might have different clinical manifestations than adult pSS. We describe a 13-year-old girl with multiple episodes of bilateral parotid swelling lasting 2 years. Her history included severe arthralgia, local edema, and purpura episodes since 9 years of age. During her 3-week hospitalization, 2 episodes of parotid swelling occurred, which both resolved in 48 hours. Ultrasonography and magnetic resonance images of parotid glands showed parenchymal inhomogeneity related to adipose degeneration and nodular pattern. Investigations showed elevated erythrocyte sedimentation rate, the presence of hypergammaglobulinemia, positive antinuclear antibody, and elevated rheumatoid factor, anti-Sjogren syndrome antigen A, and anti-Sjogren syndrome antigen B. Histopathologic examination of labial minor salivary glands revealed focal periductal lymphocytic infiltrate and sialoduct ectasia. She was diagnosed as having pSS. Recurrent parotid swelling is a more characteristic feature of disease in children, and this finding should alert the clinician to the possible diagnosis of PSS

Evaluation of (99m)Technetium-Vancomycin Imaging Potential in Experimental Rat Model for the Diagnosis of Infective Endocarditis

Background: Infective endocarditis (IE) is an infection of the heart's endocardial surface. In recent years, nuclear imaging methods have gained importance in the diagnosis of IE. The present study aims to investigate the imaging potential of Tc-99m-labeled vancomycin (Tc-99m-Van-comycin) as a new agent that would enable the diagnosis of IE in its early stages when it is difficult to diagnose or has small vegetation in the experimental rat model