Multidimensional Meaning, Existing Problems and Optimization Path for the Management of Coaches in Chinese University Basketball League

A well-managed level of competition and training by coaches is an essential catalyst for the achievement of talent development goals in the Chinese University Basketball League. This study compares the multi-dimensional meaning of the management of coaches in the Chinese College Basketball League, and analyses the existing management problems based on the SMART principle, the 4P model of human resource management, and the GROW model, to propose feasible measures to optimize the management of coaches. This research aims to provide a theoretical reference and practical basis for the improvement of the management and to provide a driving force for the realization of the long-term goal of talent training in the Chinese University Basketball League

Study on failure behaviors and control technology of surrounding rock in a weakly cemented soft rock roadway: A case study

During coal mining, the deformation and failure of a weakly cemented soft rock roadway roof could cause difficulties for roadway support. In this paper, a combination of on-site measurement and theoretical analysis is used to solve this issue. Firstly this paper investigates the in situ deformation and failure behaviors of a soft rock roadway in a mine in Western China. Then, the failure mechanism and corresponding support principles are discussed and given. Third, various support schemes (bolt and cable reinforcement optimization, grouting, and single prop + top beam combined reinforcement) are proposed and tested. Results show the support capacity can meet the requirements after optimizing the bolt and cable reinforcement support. Due to the development of roof cracks and low grouting pressure, the grouting slurry did not completely fill the roof cracks, resulting in a poor roof control effect. The passive support of a “single prop + top beam” can effectively control the roof subsidence and achieve good application results

Experimental investigation on the effects of bed slope and tailwater on dam-break flows

YesUnderstanding of the characteristics of dam-break flows moving along a sloping wet bed can help to timely issue flood warning and risk mitigation. In this study, laboratory experiments are carried out in a large flume for a wide range of upstream water depth, bed slopes and tailwater depth. The water level is recorded and processed to calculate the mean velocity and wave celerity. Results show that the increase of the bed slope will significantly accelerate the wave-front celerity for the downstream dry bed, while the negative wave celerity will decrease. When water depth ratio α ≥ 0.3 (defined as the ratio of initial downstream water depth over the upstream water depth of dam), there are extra negative waves propagating towards the reservoir area after the flow has developed for a period of time. When α ≥ 0.6, there are the Favre waves propagating downstream. The water level and the mean velocity fluctuate due to the influence of the extra negative waves and the Favre waves. Such fluctuant frequency increases with the increase of the water depth ratio. The empirical formulas are obtained for the celerity of the first extra negative wave and the first downstream wave. The variation of wave-front height is very similar under three bed slopes investigated in this study, while the maximum wave-front height occurs when α = 0.2. The present study broadens the understanding of the effects of the bed slope and the tailwater level on the movement of the dam-break flows. Furthermore, experimental results are also compared with some analytical solutions. The validity of the assumptions made during the development of these analytical solutions and their limitations are discussed by comparing with the experimental measurements.The National Natural Science Foundation of China (Grant No: 51879179), the Open Fund from the State Key Laboratory of Hydraulics and Mountain River Engineering, Sichuan University (SKHL1809) and Sichuan Science and Technology Program (No. 2019JDTD0007)

The Role of PTHLH in Ovarian Follicle Selection, Its Transcriptional Regulation and Genetic Effects on Egg Laying Traits in Hens

In hens, follicle selection is an important process affecting egg laying traits. This study investigated the role of parathyroid hormone-like hormone (PTHLH) in chicken follicle selection, its transcriptional regulation and genetic effects on egg laying traits. PTHLH and its receptor PTH1R were mainly expressed in follicles of 6–8 mm in diameter, exhibits differential expression pattern in the theca and granulosa cells of pre- and hierarchal follicles. PTHLH stimulates the proliferation of follicular granulosa and theca cells, the expression of StAR and CYP11A1 mRNA and the production of progesterone (P4) in pre-hierarchal follicles. Treatment with FSH increased PTHLH mRNA expression in pre-hierarchal follicular theca cells and hierarchal follicular granulosa cells. Two critical regions regulating chicken PTHLH transcription were revealed, each of which harbored a SNP: C>T (chr1: 72530014) for AP-1 and a SNP: A>G (chr1: 72531676). Hens with diplotype AC/GT were younger at first laying and laid more eggs at 32 weeks. The haplotype (G-1827T-165) with double mutations had the greatest promoter activity of chicken PTHLH transcription. Collectively, PTHLH plays an important role in chicken follicle selection by stimulating cell proliferation and steroidogenesis. Polymorphisms in chicken PTHLH promoter region are associated with egg laying traits by affecting the binding of transcription factor AP-1

Primary Study for the Therapeutic Dose and Time Window of Picroside II in Treating Cerebral Ischemic Injury in Rats

The aim of this study was to explore the optimal therapeutic dose and time window of picroside II for treating cerebral ischemic injury in rats according to the orthogonal test. The middle cerebral artery occlusion (MCAO) models were established by intraluminally inserting a thread into middle cerebral artery (MCA) from left external carotid artery (ECA). The successful rat models were randomly divided into 16 groups according to the orthogonal layout of [L16(45)] and treated by injecting picroside II intraperitoneally with different doses at various times. The neurological behavioral function was evaluated by Bederson’s test and the cerebral infarction volume was measured by tetrazolium chloride (TTC) staining. The expressions of neuron specific enolase (NSE) and neuroglial mark-protein S-100 were determined by immunohistochemisty assay. The results indicated that the optimal compositions of the therapeutic dose and time window of picroside II in treating cerebral ischemic injury were ischemia 1.5 h with 20 mg/kg body weight according to Bederson’s test, 1.0 h with 20 mg/kg body weight according to cerebral infarction volume, 1.5 h with 20 mg/kg body weight according to the expressions of NSE and S-100 respectively. Based on the principle of the minimization of medication dose and maximization of therapeutic time window, the optimal composition of the therapeutic dose and time window of picroside II in treating cerebral ischemic injury should be achieved by injecting picroside II intraperitoneally with 20 mg/kg body weight at ischemia 1.5 h

Local Strong Solution for a Class of Shear Thickening Fluids with Non-Newtonian Potential and Heat-Conducting

The aim of this paper is to discuss the model for a class of shear thickening fluids with non-Newtonian potential and heat-conducting. Existence and uniqueness of local strong solutions for the model are proved. In this paper, there exist two difficulties we have to overcome. One is the strong nonlinearity of the system. The other is that the state function is not fixed