Comparison of two in situ corneal donation technique: morgue trephination or scleracorneal removal technique.

To compare the two different 'in situ' methods of corneal trephination technique under morgue condition (morgue trephination technique, MTT) and classic scleracorneal removal technique (SRT)

Analysis of a novel high performance induction air heater

UNVER, Umit/0000-0002-6968-6181; KELESOGLU, Alper/0000-0001-7139-6653WOS: 000441484700007This study represents an experimental and numerical investigation of the enhanced prototypes of the induction air heaters. For this purpose, flow field is enhanced in order to avoid turbulence. The air mass flow rate, outlet construction and the application of insulation of the outer surface of the heater were selected as the performance enhancing parameters. Depending on the exit construction, the new designed prototypes are named as K-2 and K-3. Experiments were performed under two groups for three various flow rates. In the first group, non-insulation situation is examined. In the second group tests, insulation is applied to the outside of windings and inlet-outlet flaps which constitute the boundary of the control volume for the prevention of heat losses. The increasing flow rate boosted the thermal efficiency by 9%. Each of insulation and enlarging exit cross section increased the thermal efficiency by 13%. It was observed that the thermal power transferred to air with the new prototypes increased about 246 W more than the previous designs. The thermal efficiencies of the K-2 and K-3 type heaters were calculated as 77.14% and 87.1%, respectively.University of Yalova Scientific Research Coordination Unit [2015/YL/059]This study was granted by University of Yalova Scientific Research Coordination Unit with the Project No:2015/YL/059. We would like to thank I. Muzaffer UNVER from KEMAS Co. and Mehmet OZDESLIK from Sistem Teknik Co. for their valuable contributions in this study

Analysis of a novel high performance induction air heater

This study represents an experimental and numerical investigation of the enhanced prototypes of the induction air heaters. For this purpose, flow field is enhanced in order to avoid turbulence. The air mass flow rate, outlet construction and the application of insulation of the outer surface of the heater were selected as the performance enhancing parameters. Depending on the exit construction, the new designed prototypes are named as K-2 and K-3. Experiments were performed under two groups for three various flow rates. In the first group, non-insulation situation is examined. In the second group tests, insulation is applied to the outside of windings and inlet-outlet flaps which constitute the boundary of the control volume for the prevention of heat losses. The increasing flow rate boosted the thermal efficiency by 9%. Each of insulation and enlarging exit cross section increased the thermal efficiency by 13%. It was observed that the thermal power transferred to air with the new prototypes increased about 246 W more than the previous designs. The thermal efficiencies of the K-2 and K-3 type heaters were calculated as 77.14% and 87.1%, respectively

Analysis of the effect of construction parameters on energetic and exergetic efficiency of induction air heaters

KELESOGLU, Alper/0000-0001-7139-6653; UNVER, Umit/0000-0002-6968-6181WOS: 000428177300005This study is concerned with the energy and exergy efficiency analysis of a novel air heater that operates with induction principle. The aim of this paper is investigation of the energy and the exergy efficiency augmentation of the new K-1 induction air heater prototype. Energy and exergy performance of the K-1 prototype was analysed and compared with the previous K-0 prototype. The analyses were performed with experimental study and with computational fluid dynamics (CFD) simulations. The new design boosted the energy efficiency about 22.98%. The exergy efficiency was calculated to be around 11.5% max. The CFD simulation results showed that a 1 m/s increase in the inlet velocity yields 3.1% and 0.06% augmentation in the energy and the exergy efficiency respectively. The inlet temperature increase negatively affects the energy and the actual exergy efficiencies. It was concluded that efficiencies of these heaters can be enhanced with more appropriate construction

Effect of Local Infiltration Analgesia on Functional Outcomes in Total Knee Arthroplasty: A Randomized, Placebo-Controlled, Double-Blind Clinical Trial

Local infiltration analgesia (LIA) is a simple, surgeon-administered technique for the treatment of postoperative pain after total knee arthroplasty (TKA). The aim of the study was to investigate the efficacy of LIA and its effects on functional outcomes in TKA. A total of 135 patients with primary TKA were recruited and randomized either to receive LIA or to receive placebo injection (PI). Pain, active range of motion (ROM), knee function score, functional activities, and hospital length of stay (LOS) were assessed before surgery and from postoperative day (POD) 1 to at discharge. Lower pain scores at rest were recorded on POD1 and POD2 in the LIA group (p = 0.027 andp = 0.020, respectively). Lower pain score on walking was recorded on POD1 in the LIA group (p = 0.002). There was a statistically significant difference in active knee flexion between groups on POD1 (p = 0.038). There was a significant difference in LOS between LIA and PI groups. Shorter stay was seen in LIA group. There were no statistically significant differences between the groups in terms of knee function score and functional outcomes. LIA technique is effective for pain management in the early postoperative period. LIA added benefit for knee function in terms of active knee flexion ROM after TKA. A shorter hospital LOS was observed in LIA group. However, we did not find any differences in groups in terms of functional assessment such as ability to rise from a chair and walking capacity.The level of evidence is randomized controlled trial, level I

Serum paraoxonase (a high-density lipoprotein-associated lipophilic antioxidant) activity in clinical follow-up of patients with acute pancreatitis, with particular emphasis on oxidative stress parameters and lipid profile: a prospective pilot trial

The purpose of this study was to investigate the possible role of PON-1, an antioxidant lipophilic enzyme linked to HDL-C (high-density lipoprotein cholesterol), on the pathophysiology and clinical follow-up of acute pancreatitis. Biochemical tests, PON-1 and oxidative stress parameters (malonyl dialdehyde, MDA; superoxide dismutase, SOD; total antioxidant capacity, TAC) were evaluated in the sera of patients with acute pancreatitis at admission (day 0), day 3 and day 10 of follow-up, between June and September 2017. SPSS 13.0 statistical software package programme was used for statistical analyses.Mean age was 51.4 of the total 25 patients. Ranson scores were 0–1 points (60%), 3–4 points (24%) and 5–6 points (16%). CTSI (computed tomography severity index) scores were calculated, and most of the patients were seen to have mild or average pancreatitis (96%). While total cholesterol, triacylglycerol and LDL-C (low-density lipoprotein) levels stayed in their normal limits, there was a significant decrement tendency. HDL-C level was seen to rise significantly above its upper limit at day 10 (p < 0.001). Mean PON-1 levels were measured as 69.23, 76.72 vs. 113.15 U/mL at days 0, 3 and 10, respectively; and it was positively correlated with HDL-C (p < 0.001). Serum SOD increased also in parallel with PON-1 (20.49 vs. 39.46 U/mL) while MDA level decreased significantly (3.9 vs. 2.28 μM, p < 0.001). TAC was seen to rise significantly after treatment (0.52 vs. 1.22 mM). In conclusion, decreased PON-1 and HDL-C together with antioxidants SOD and TAC at the early period of acute pancreatitis were seen to rise after treatment, while the previously higher MDA level decreased in parallel. This reveals the importance of the balance between oxidative stress and antioxidant defense mechanisms in clinical progression of the disease, and the potential of PON-1 as a promising clinical marker

The role of human epididymis secretory protein E4 in patients with endometrial cancer and premalignant endometrial lesions

We evaluated the concentrations of human epididymis secretory protein E4 (HE4) and Ca-125 in relation to clinicopathologic features in patients with endometrial cancer and premalignant endometrial lesions. Women with abnormal uterine bleeding (n = 167) who underwent endometrial sampling were divided into four groups. Group 1: endometrial cancer (n = 68), group 2: atypical endometrial hyperplasia (n = 12), group 3: endometrial hyperplasia without atypia (n = 39) and group 4: controls (n = 48). Women with endometrial cancer exhibited higher concentrations of HE4 levels than controls (91.4 pmol/L vs. 46.2 pmol/L, p < 0.001). HE4 levels were significantly higher in patients with lymphatic involvement, deep myometrial invasion, lymphovascular space involvement and non-endometrioid histology (p < 0.001). The sensitivity, specificity, positive and negative predictive values for HE4 in detecting endometrial cancer were 72.7%, 84.4%, 80% and 78.4%, respectively. Preoperative HE4 levels are more elevated in women with endometrial cancer than those with benign endometrium as well as in women with prognostic high-risk factors with endometrial cancer. HE4 may be used as an additional marker in combination with other clinicopathologic features for planning the treatment

Turkish Guideline for Diagnosis and Treatment of Allergic Rhinitis (ART)

Object: To prepare a national guideline for Oto-rhinolaryngologist who treat allergic rhinitis patient