4,950 research outputs found

    A Study of Environmental Sustainability Hidden in the Traditional Korean Residences through Computational Analysis Tool

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    This research extracts the environmental design responses of the traditional Korean residences through a holistic computational analysis tool referred to as Ecotect. Ecotect is used to generate intersections with design analysis and perform various environmental solutions. Three traditional Korean residences - Yeongyeongdang, Unjoru, and Chusagotaek during the Joseon dynasty (AD1392~1910) of Korea are tested. Furthermore, Ecotect is used to demonstrate the environmental design response in detail with parameters such as shadows, shading, solar analysis, wind flow, and thermal performance. Taking into consideration the social and cultural impact of the Joseon dynasty, the performances of the various design solutions are analyzed, explaining the impact that different building elements have on energy consumption. The relationships are represented in the form of statistical relations and interactive data charts. This research will also: (i) introduce methodologies to the holistic buildingsā€™ energy performance, (ii) implement the aforementioned method in analyzing the three traditional Korean residences, (iii) view three traditional residencesā€™ range of environmental design responses through computational analysis, (iv) deal in depth the environmental design responses that enhance the thermal comfort in the traditional residences, (v) and lastly, make suggestions based on the outcome of this study for future research

    The impact of a firmā€™s make, pseudoĆ¢ make, or buy strategy on product performance

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    The bulk of the product architecture and makeĆ¢ buy choice literature deals with product architecture changes from integral to modular form. This development is often associated with a firmā€™s tendency to change from a make to a buy strategy. However, a few studies investigate the change of product architecture in the reverse direction Ć¢ from modular to integral form Ć¢ and the subsequent change in the firm sourcing decision from a buy to a make strategy. These studies hold to the presumption that a firm following a make strategy will outperform firms following a buy strategy in dealing with integral product architectures. Based on the knowledgeĆ¢ based view, we argue for the viability of a sourcing strategy between the pure make and buy strategies Ć¢ a pseudoĆ¢ make strategy. We also argue that as product architecture changes from a modular to integral form, firms adopting this pseudoĆ¢ make strategy are likely to show better product performance than firms following a pure make or buy strategy due to the relative knowledge advantages of the pseudoĆ¢ make strategy in dealing with the integral product architecture. We examine the impact of the make/pseudoĆ¢ make/buy strategies on product performance in the U.S. bicycle derailleur and freewheel market from 1980 to 1992 and provide theoretical and managerial implications of our results. Our findings highlight an important distinction between the pseudoĆ¢ make and makeĆ¢ buy strategies that has not previously been fully appreciated in the extant literature, and as a result increases our understanding of why some firms do not switch strategies from a buy to a make strategy when product architecture changes from modular to integral form as previously expected.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/146818/1/joom289.pd

    Synergistic multi-doping effects on the Li7La3Zr2O12 solid electrolyte for fast lithium ion conduction.

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    Here, we investigate the doping effects on the lithium ion transport behavior in garnet Li7La3Zr2O12 (LLZO) from the combined experimental and theoretical approach. The concentration of Li ion vacancy generated by the inclusion of aliovalent dopants such as Al(3+) plays a key role in stabilizing the cubic LLZO. However, it is found that the site preference of Al in 24d position hinders the three dimensionally connected Li ion movement when heavily doped according to the structural refinement and the DFT calculations. In this report, we demonstrate that the multi-doping using additional Ta dopants into the Al-doped LLZO shifts the most energetically favorable sites of Al in the crystal structure from 24d to 96ā€‰h Li site, thereby providing more open space for Li ion transport. As a result of these synergistic effects, the multi-doped LLZO shows about three times higher ionic conductivity of 6.14ā€‰Ć—ā€‰10(-4)ā€‰S cm(-1) than that of the singly-doped LLZO with a much less efforts in stabilizing cubic phases in the synthetic condition

    Orai1 inhibitor STIM2?? regulates myogenesis by controlling SOCE dependent transcriptional factors

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    Store-operated Ca2+ entry (SOCE), the fundamental Ca2+ signaling mechanism in myogenesis, is mediated by stromal interaction molecule (STIM), which senses the depletion of endoplasmic reticulum Ca2+ stores and induces Ca2+ influx by activating Orai channels in the plasma membrane. Recently, STIM2??, an eight-residue-inserted splice variant of STIM2, was found to act as an inhibitor of SOCE. Although a previous study demonstrated an increase in STIM2?? splicing during in vitro differentiation of skeletal muscle, the underlying mechanism and detailed function of STIM2?? in myogenesis remain unclear. In this study, we investigated the function of STIM2?? in myogenesis using the C2C12 cell line with RNA interference-mediated knockdown and CRISPR-Cas-mediated knockout approaches. Deletion of STIM2?? delayed myogenic differentiation through the MEF2C and NFAT4 pathway in C2C12 cells. Further, loss of STIM2?? increased cell proliferation by altering Ca2+ homeostasis and inhibited cell cycle arrest mediated by the cyclin D1-CDK4 degradation pathway. Thus, this study identified a previously unknown function of STIM2?? in myogenesis and improves the understanding of how cells effectively regulate the development process via alternative splicing

    Two Higgs doublet models for the LHC Higgs boson data at s=\sqrt{s}= 7 and 8 TeV

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    Updated LHC data on the new 126 GeV boson during the 7 and 8 TeV runnings strengthen the standard model Higgs boson interpretation further. Through the global Ļ‡2\chi^2 analysis, we investigate whether the new particle could be one of the scalar particles in two Higgs doublet models. Four types (Type I, II, X and Y) are comprehensively studied. Taking the recent analysis on the spin-parity of the new boson, we consider two scenarios: the new boson is either the light CP-even one (h0h^0) or the heavy CP-even one (H0H^0). It is found that both scenarios are consistent with the new data, not only in the parameter regions near the decoupling limit but also in other regions far from the decoupling limit. In addition, the current data are compatible with the possibility that the light Higgs boson h0h^0 is hidden in the mass window of 90-100 GeV. The diphoton or Ļ„Ļ„\tau\tau channel can provide a probe of this possibility by the enhanced signal rates.Comment: To appear in JHE
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