509 research outputs found

    Job embeddedness theory : can it help explain employee retention?.

    Get PDF
    Job embeddedness theory, as introduced by Mitchell, Holtom, Lee, Sablynski, and Erez (2001), offers a method of discovering why people stay in an organization. By analyzing the construct\u27s three dimensions (links, fit, and sacrifice) within community and workplace contexts, an overall level of embeddedness was determined and then used to examine retention among Extension agents (N = 454) in the Kansas and Kentucky Extension Services systems. An Internet-based survey was used to gather background data and responses to various scales (embeddedness, job satisfaction, organization commitment, engagement, intent to stay, and discretionary effort). Research questions were examined through the use of correlations, analyses of variance, and linear regression analyses. This dissertation is divided into five chapters. Chapter 1 gives a historical overview of the problem of retention. Chapter 2 examines the major theories that scholars have used to explain retention and the factors that influence it; particular attention is given to job embeddedness theory. Chapter 3 contains a discussion of the research design, study population and sample, sampling procedure, instrumentation, and datacollection procedures. Chapter 4 presents the results of the study. The chapter presents the main analysis and more specific analyses by the study population\u27s demographics (including comparisons of nonrespondents, respondents, and late respondents). Chapter 5 provides a summary of the study; a discussion of the results; implications for theory, research, and practice; and a discussion of the study\u27s limitations. In summary, Kansas and Kentucky Extension agents reported significantly different levels of job embeddedness over the study period. Regression analyses showed that job embeddedness was significantly correlated with and predicted unique variance in intent to stay. An examination of the participants\u27 background characteristics showed that age, education level, and geographic state of employment significantly influenced certain components of job embeddedness

    Urban Extension–Reflections on the Past–A Look to the Future

    Get PDF
    The Cooperative Extension Service (Extension) has built an outstanding reputation by serving clientele in rural areas. The organization’s credibility in the past has rested solidly on those stakeholders who have advocated for Extension’s continued existence due to its success in helping rural communities move beyond societal ills. With the rapid expansion of urban America, Extension’s potential for growth is tremendous—if the organization can adapt to meet the needs of metropolitan communities. This article features highlights of the successes and barriers presented by previous studies and makes suggestions on what can be done to move the urban Extension agenda forward. The authors share results of a case study in Kentucky in hopes of offering current and future recommendations for the many Extension systems across the country challenged with being as relevant a resource to urban areas as the organization is to its rural counterparts

    Extension and Faith-Based Organizations – Understanding Past and Present Linkages and Future Opportunities for Urban Communities

    Get PDF
    This examination of the literature explored the limited empirical data available regarding the networks formed between Cooperative Extension (Extension), local partners, and faith-based organizations (FBOs) within metropolitan areas. With FBOs being central to rural towns, as well as urban neighborhoods, Extension must consider engaging with these essential community resources as a means to broaden its reach and serve a wider audience. Not only are these entities underutilized, despite the abundance of human and social capital they provide, but they too are often in need of what Extension has to offer. This article will examine the history of collaborations between urban FBOs and Extension. In addition, the authors will look at how applying the principles of past successes to current problems could potentially enrich urban societies. The authors suggest meaningful ways in which Extension can serve in a capacity that is beneficial but not imposing on moral and/or spiritual beliefs and serve as allies with faith-based organizations to reach and aid new and/or underserved clientele

    Job Embeddedness Theory: Can It Help Explain Employee Retention Among Extension Agents?

    Get PDF
    The study reported here examined Job Embeddedness theory, as introduced by Mitchell, Holtom, Lee, Sablynski, and Erez (2001), which offers a method of discovering why people stay in an organization. Extension agents in two states (N=454) reported significantly different levels of job embeddedness during the study period. Regression analyses showed that job embeddedness was significantly correlated with and predicted unique variance in intent to stay

    Targeting Neuropeptides to Bone Fractures for Accelerated Healing

    Get PDF
    In patients over the age of 65 especially, bone fractures represent a significant disease burden. Non-invasive drug therapies are not available for bone fractures which represents a problem for this population. Vasoactive intestinal peptide (VIP) and Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP), two neuromodulator peptides in the glucagon superfamily, have demonstrated positive regulation of osteoblast proliferation and activity. Using acidic oligopeptides, we have developed ligands that target to and accumulate at fracture sites. These targeting ligands can be synthesized in sequence with bone anabolic peptides to minimize off target effects and increase potency at the fracture site to create safer and more efficacious therapeutic molecules. The conjugation of PACAP and VIP to acidic oligopeptide targeting ligands results in compounds that demonstrate significant improvements in regeneration of bone at fracture site in vivo in terms of strength and mineralization of fracture callus

    The Sex and Race Specific Relationship between Anthropometry and Body Fat Composition Determined from Computed Tomography: Evidence from the Multi-Ethnic Study of Atherosclerosis.

    Get PDF
    BackgroundFew studies have investigated the relationship of anthropometric measurements with computed tomography (CT) body fat composition, and even fewer determined if these relationships differ by sex and race.MethodsCT scans from 1,851 participants in the population based Multi-Ethnic Study of Atherosclerosis were assessed for visceral and subcutaneous fat areas by semi-automated segmentation of body compartments. Regression models were used to investigate relationships for anthropometry with visceral and subcutaneous fat separately by sex and race/ethnicity.ResultsParticipants were 50% female, 41% Caucasian, 13% Asian, 21% African American, and 25% Hispanic. For visceral fat, the positive relationship with weight (p = 0.028), waist circumference (p<0.001), waist to hip ratio (p<0.001), and waist to height ratio (p = 0.05) differed by sex, with a steeper slope for men. That is, across the range of these anthropometric measures the rise in visceral fat is faster for men than for women. Additionally, there were differences by race/ethnicity in the relationship with height (p<0.001), weight (p<0.001), waist circumference (p<0.001), hip circumference (p = 0.006), and waist to hip ratio (p = 0.001) with the Hispanic group having shallower slopes. For subcutaneous fat, interaction by sex was found for all anthropometric indices at p<0.05, but not for race/ethnicity.ConclusionThe relationship between anthropometry and underlying adiposity differs by sex and race/ethnicity. When anthropometry is used as a proxy for visceral fat in research, sex-specific models should be used

    In silico discovery of transcription regulatory elements in Plasmodium falciparum

    Get PDF
    <p>Abstract</p> <p>Background</p> <p>With the sequence of the <it>Plasmodium falciparum </it>genome and several global mRNA and protein life cycle expression profiling projects now completed, elucidating the underlying networks of transcriptional control important for the progression of the parasite life cycle is highly pertinent to the development of new anti-malarials. To date, relatively little is known regarding the specific mechanisms the parasite employs to regulate gene expression at the mRNA level, with studies of the <it>P. falciparum </it>genome sequence having revealed few <it>cis</it>-regulatory elements and associated transcription factors. Although it is possible the parasite may evoke mechanisms of transcriptional control drastically different from those used by other eukaryotic organisms, the extreme AT-rich nature of <it>P. falciparum </it>intergenic regions (~90% AT) presents significant challenges to <it>in silico cis</it>-regulatory element discovery.</p> <p>Results</p> <p>We have developed an algorithm called Gene Enrichment Motif Searching (GEMS) that uses a hypergeometric-based scoring function and a position-weight matrix optimization routine to identify with high-confidence regulatory elements in the nucleotide-biased and repeat sequence-rich <it>P. falciparum </it>genome. When applied to promoter regions of genes contained within 21 co-expression gene clusters generated from <it>P. falciparum </it>life cycle microarray data using the semi-supervised clustering algorithm Ontology-based Pattern Identification, GEMS identified 34 putative <it>cis</it>-regulatory elements associated with a variety of parasite processes including sexual development, cell invasion, antigenic variation and protein biosynthesis. Among these candidates were novel motifs, as well as many of the elements for which biological experimental evidence already exists in the <it>Plasmodium </it>literature. To provide evidence for the biological relevance of a cell invasion-related element predicted by GEMS, reporter gene and electrophoretic mobility shift assays were conducted.</p> <p>Conclusion</p> <p>This GEMS analysis demonstrates that <it>in silico </it>regulatory element discovery can be successfully applied to challenging repeat-sequence-rich, base-biased genomes such as that of <it>P. falciparum</it>. The fact that regulatory elements were predicted from a diverse range of functional gene clusters supports the hypothesis that <it>cis</it>-regulatory elements play a role in the transcriptional control of many <it>P. falciparum </it>biological processes. The putative regulatory elements described represent promising candidates for future biological investigation into the underlying transcriptional control mechanisms of gene regulation in malaria parasites.</p

    Lessons Learned in the Early Stages of a Community-Academic Partnership to Address Health Disparities in a Rural Community

    Get PDF
    In rural Georgia, African American men are burdened by chronic health diseases such as cancer, diabetes, and cardiovascular disease. Community-academic partnerships that leverage community-based participatory research (CBPR) principles can facilitate the adaptation and translation of multilevel programs to address chronic disease prevention and management in rural areas. The objective of this study was to explore key components of the CBPR process that bolstered the early stages of a partnership established between rural-residing community leaders and academic partners in Georgia. Qualitative methodology was used to collect and assess data regarding the initial engagement between the community and academic partners. Findings indicate that five components supported initial engagement: utilizing the public service and outreach arm of the university to connect with rural communities; creating synergy around identified community health needs; encouraging community members to provide input into the research design to ensure the research goals reflect community values; enhancing the capacity of community partners; and following the lead of the community. Findings provide insights into how to begin engaging rural communities in the southeast in order to strengthen the adaptation and translation of initiatives to improve cancer, diabetes and cardiovascular disease outcomes

    New branched Porolithon species (Corallinales, Rhodophyta) from the Great Barrier Reef, Coral Sea, and Lord Howe Island

    Get PDF
    Porolithon is one of the most ecologically important genera of tropical and subtropical crustose (non-geniculate) coralline algae growing abundantly along the shallow margins of coral reefs and functioning to cement reef frameworks. Thalli of branched, fruticose Porolithon specimens from the Indo-Pacific Ocean traditionally have been called P. gardineri, while massive, columnar forms have been called P. craspedium. Sequence comparisons of the rbcL gene both from type specimens of P. gardineri and P. craspedium and from field-collected specimens demonstrate that neither species is present in east Australia and instead resolve into four unique genetic lineages. Porolithon howensis sp. nov. forms columnar protuberances and loosely attached margins and occurs predominantly at Lord Howe Island; P. lobulatum sp. nov. has fruticose to clavate forms and free margins that are lobed and occurs in the Coral Sea and on the Great Barrier Reef (GBR); P. parvulum sp. nov. has short (<2 cm), unbranched protuberances and attached margins and is restricted to the central and southern GBR; and P. pinnaculum sp. nov. has a mountain-like, columnar morphology and occurs on oceanic Coral Sea reefs. A rbcL gene sequence of the isotype of P. castellum demonstrates it is a different species from other columnar species. In addition to the diagnostic rbcL and psbA marker sequences, the four new species may be distinguished by a combination of features including thallus growth form, margin shape (attached or unattached), and medullary system (coaxial or plumose). Porolithon species, because of their ecological importance and sensitivity to ocean acidification, need urgent documentation of their taxonomic diversity

    Injury Scores and Spatial Responses of Wolves Following Capture: Cable Restraints Versus Foothold Traps

    Get PDF
    Wolves (Canis lupus) have been captured with foothold traps for several decades to equip them with radiocollars for population monitoring. However, trapping in most areas is limited to spring, summer, and autumn as cold winter temperatures can lead to frozen appendages in trapped animals. In addition, conflicts arise when domestic dogs encounter these traps in nonwinter seasons. An alternative capture method is the use of cable restraint devices (modified neck snares) in the winter. We evaluated injury scores, movement patterns, and space use of wolves captured in cable restraint devices and foothold traps in north‐central Minnesota, USA, during 2012–2016. Injury scores did not differ between capture techniques; however, movement patterns and space use were different. We found that the movement away from the capture site appeared to plateau by approximately 8–10 days for wolves captured by either foothold traps or cable restraints, but wolves captured in traps travelled farther away. Daily movement rates reached an asymptote approximately 14 days earlier for wolves captured with cable restraints as compared with wolves caught with foothold traps. We found the space use among wolves caught with cable restraint devices plateaued in a shorter time frame than wolves caught with foothold traps whether using days since capture (38 days earlier) or number of locations (149 locations earlier). When we controlled for seasonal effects and the presence of a capture using locational data collected 6 months later, there was no difference in space use. We concluded that wolves captured in cable restraints recovered more quickly from the capture and resumed space use and activity patterns more rapidly than wolves captured with foothold traps. Published 2019. This article is a U.S. Government work and is in the public domain in the USA
    • 

    corecore