4,274 research outputs found
Identifying Optimal Technical and Tactical Performance Characteristics in Australian Football
This study identified the optimal technical and tactical performance characteristics of Australian football teams. The application of machine learning approaches identified the key indicators of successful AFL teams. The main findings of this research provide an evidence-base for key stakeholders to inform their training and match day decisions
Deuce: A Lightweight User Interface for Structured Editing
We present a structure-aware code editor, called Deuce, that is equipped with
direct manipulation capabilities for invoking automated program
transformations. Compared to traditional refactoring environments, Deuce
employs a direct manipulation interface that is tightly integrated within a
text-based editing workflow. In particular, Deuce draws (i) clickable widgets
atop the source code that allow the user to structurally select the
unstructured text for subexpressions and other relevant features, and (ii) a
lightweight, interactive menu of potential transformations based on the current
selections. We implement and evaluate our design with mostly standard
transformations in the context of a small functional programming language. A
controlled user study with 21 participants demonstrates that structural
selection is preferred to a more traditional text-selection interface and may
be faster overall once users gain experience with the tool. These results
accord with Deuce's aim to provide human-friendly structural interactions on
top of familiar text-based editing.Comment: ICSE 2018 Paper + Supplementary Appendice
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Feeling Small: Exploring the Tactile Perception Limits
The human finger is exquisitely sensitive in perceiving different materials, but the question remains as to what length scales are capable of being distinguished in active touch. We combine material science with psychophysics to manufacture and haptically explore a series of topographically patterned surfaces of controlled wavelength, but identical chemistry. Strain-induced surface wrinkling and subsequent templating produced 16 surfaces with wrinkle wavelengths ranging from 300 nm to 90 μm and amplitudes between 7 nm and 4.5 μm. Perceived similarities of these surfaces (and two blanks) were pairwise scaled by participants, and interdistances among all stimuli were determined by individual differences scaling (INDSCAL). The tactile space thus generated and its two perceptual dimensions were directly linked to surface physical properties – the finger friction coefficient and the wrinkle wavelength. Finally, the lowest amplitude of the wrinkles so distinguished was approximately 10 nm, demonstrating that human tactile discrimination extends to the nanoscale
A carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce1 and carboxymethylation
The mammalian nuclear lamina protein lamin B1 is posttranslationally modified by farnesylation, endoproteolysis, and carboxymethylation at a carboxyl-terminal CAAX motif. In this work, we demonstrate that the CAAX endoprotease Rce1 is required for lamin B1 endoproteolysis, demonstrate an independent pool of proteolyzed but nonmethylated lamin B1, as well as fully processed lamin B1, in interphase nuclei, and show a role for methylation in the organization of lamin B1 into domains of the nuclear lamina. Deficiency in the endoproteolysis or methylation of lamin B1 results in loss of integrity and deformity of the nuclear lamina. These data show that the organization of the nuclear envelope and lamina is dependent on a mechanism involving the methylation of lamin B1, and they identify a potential mechanism of laminopathy involving a B-type lamin
Diagnosis of Fault Modes Masked by Control Loops with an Application to Autonomous Hovercraft Systems
This paper introduces a methodology for the design, testing and assessment of incipient failure detection techniques for failing components/systems of an autonomous vehicle masked or hidden by feedback control loops. It is recognized that the optimum operation of critical assets (aircraft, autonomous systems, etc.) may be compromised by feedback control loops by masking severe fault modes while compensating for typical disturbances. Detrimental consequences of such occurrences include the inability to detect expeditiously and accurately incipient failures, loss of control and inefficient operation of assets in the form of fuel overconsumption and adverse environmental impact. We pursue a systems engineering process to design, construct and test an autonomous hovercraft instrumented appropriately for improved autonomy. Hidden fault modes are detected with performance guarantees by invoking a Bayesian estimation approach called particle filtering. Simulation and experimental studies are employed to demonstrate the efficacy of the proposed methods
Role of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in Modulating Vascular Smooth Muscle Cells by Activating Large-Conductance Potassium Ion Channels
International audienceIn this chapter we propose to discuss the role of K+ ion channels in stimulating vasodilatation by altering the membrane potential of vascular smooth muscle cells. We present evidence that the K+ channels are modulated by a direct action of non-steroidal antiinflammatory drugs (NSAIDs) to activate the K+ ion channels
The GALEX Ultraviolet Atlas of Nearby Galaxies
We present images, integrated photometry, and surface-brightness and color profiles for a total of 1034 nearby galaxies recently observed by the Galaxy Evolution Explorer (GALEX) satellite in its far-ultraviolet (FUV; λ_(eff) = 1516 Å) and near-ultraviolet (NUV; λ_(eff) = 2267 Å) bands. Our catalog of objects is derived primarily from the GALEX Nearby Galaxies Survey (NGS) supplemented by galaxies larger than 1' in diameter serendipitously found in these fields and in other GALEX exposures of similar of greater depth. The sample analyzed here adequately describes the distribution and full range of properties (luminosity, color, star formation rate [SFR]) of galaxies in the local universe. From the surface brightness profiles obtained we have computed asymptotic magnitudes, colors, and luminosities, along with the concentration indices C31 and C42. We have also morphologically classified the UV surface brightness profiles according to their shape. This data set has been complemented with archival optical, near-infrared, and far-infrared fluxes and colors. We find that the integrated (FUV − K) color provides robust discrimination between elliptical and spiral/irregular galaxies and also among spiral galaxies of different subtypes. Elliptical galaxies with brighter K-band luminosities (i.e., more massive) are redder in (NUV − K) color but bluer in (FUV − NUV) (a color sensitive to the presence of a strong UV upturn) than less massive ellipticals. In the case of the spiral/irregular galaxies our analysis shows the presence of a relatively tight correlation between the (FUV − NUV) color (or, equivalently, the slope of the UV spectrum, β) and the total infrared-to-UV ratio. The correlation found between (FUV − NUV) color and K-band luminosity (with lower luminosity objects being bluer than more luminous ones) can be explained as due to an increase in the dust content with galaxy luminosity. The images in this Atlas along with the profiles and integrated properties are publicly available through a dedicated Web page
The Young and the Dustless: Interpreting Radio Observations of UltraViolet Luminous Galaxies
Ultraviolet Luminous Galaxies (UVLGs) have been identified as intensely
star-forming, nearby galaxies. A subset of these, the supercompact UVLGs, are
believed to be local analogs of high redshift Lyman Break Galaxies. Here we
investigate the radio continuum properties of this important population for the
first time. We have observed 42 supercompact UVLGs with the VLA, all of which
have extensive coverage in the UV/optical by GALEX and SDSS. Our analysis
includes comparison samples of multiwavelength data from the Spitzer First Look
Survey and from the SDSS-Galex matched catalogs. In addition we have Spitzer
MIPS data for 24 of our galaxies and find that they fall on the radio-FIR
correlation of normal star-forming galaxies. We find that our galaxies have
lower radio-to-UV ratios and lower Balmer decrements than other local galaxies
with similar (high) star formation rates. Optical spectra show they have lower
Dn(4000) and HdeltaA indices, higher Hbeta emission-line equivalents widths,
and higher [OIII]5007/Hbeta emission-line ratios than normal star forming
galaxies. Comparing these results to galaxy spectral evolution models we
conclude that supercompact UVLGs are distinguished from normal star forming
galaxies firstly by their high specific star formation rates. Moreover,
compared to other types of galaxies with similar star formation rates, they
have significantly less dust attenuation. In both regards they are similar to
Lyman Break Galaxies. This suggests that the process that causes star formation
in the supercompact UVLGs differs from other local star forming galaxies, but
may be similar to Lyman Break Galaxies.Comment: 37 pages, 13 figures, accepted and scheduled to appear in ApJS
December 2007 (GALEX Special Issue
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