The Ursinus Weekly, December 9, 1963

Ten Ursinus students named to Who\u27s who • Mrs. Randall, 942 resident head, dies Saturday • UC Circle holds Christmas party • College Bowl team prepares for meet • J. A. Minnich attends seminar • Breeches Bible used at vespers • Handel\u27s Messiah to be given at UC; 26th annual concert set for Dec. 12 • PSEA to hear talk on testing • Notes on the WSGA • Barnhouse of TV 10 speaks • Design for Living program Tuesday night • Editorial: Curtain Club meets the challenge; Constitutional controls viewed • Reaction from abroad: Stockholm; Tokyo • Letters to the editor • Dear Wormwood: Theatre in the round a success at UC • Greek gleanings • Ivory tower • The kaleidoscope student: In review • John Acton will speak to Young Republicans • Troster guides UC quintet to opening victory • Intramural corner • Smiley and Day get hockey honors • Soccer team ends season with 4-5-2 • Weisel elected unsung herohttps://digitalcommons.ursinus.edu/weekly/1260/thumbnail.jp

The Ursinus Weekly, March 7, 1966

Senior Symposium tours Phila. settlement homes • Curtain Club lists Spring dramatics • The Ballet Chaffee to be Wednesday evening Forum • Folk Society donates $250 • Y to present Accion leader • Swann receives memorial scholarship • Temple begins math internship • Editorial: The apathetic syndrome • Young and old, rich and poor accepted by Admissions Office: 81% of present freshmen placed near top of class • Dolman stresses importance of Admissions interviews • Letter to the editor • Swim team soaks Temple; Drops one to E. S\u27burg • Girls B\u27ball team drops game to WC • Intramural corner • Bears make creditable showing in MACs • 1965-1966 wrestling roundup • Greek gleanings • Players parody modern lifehttps://digitalcommons.ursinus.edu/weekly/1219/thumbnail.jp

The Ursinus Weekly, December 6, 1965

Weekly announces new staff members • Juniors initiate Prom innovation • Autistic child subject of Psych Club meeting • 28th Messiah performance features soloists Mayes, Valente, Jones and Mayer • Career conference scheduled for Dec. 7, 8 and 9 • Spanish Club offers UNICEF Christmas cards • Senses explored in Moody film • Retzlaff to address MSGA Christmas banquet • Phila. alumni elect regional president • Christmas events • Editorial: The Ursinus story • Theater-in-the-round scores instant success with audience • Klatsch speaker upholds liberal playboy philosophy • Letters to the editor • Mormons amaze UC\u27ers attending YMCA forum • Soccer-Football wrap-up • Kamela named All-American • Sue Day makes All-American hockey team • Cagers win openers: E. Baptist bows to Bears 67-63 • Intramural corner • Basketball-wrestling preview 1965-66 • Greek gleanings • Ursinus band shuns practices yet sounds bigger than life: Unit depends on quality musicians in performances • Moonlight and mistletoe promhttps://digitalcommons.ursinus.edu/weekly/1212/thumbnail.jp

The Ursinus Weekly, January 10, 1966

Senate urges reading period before exams • The Freeland story • The Ursinus plan: To advance the quality of education at UC • UC receives $25,000 grant • Alumni fund hits new peak in contributions • Lantern contest proclaims winners • Roster changes • Examination schedule • We\u27ll not forget: A promise to Freeland; Old building to be razed to provide Library site • A senior\u27s view of Freeland: Can Library replace Freeland\u27s primacy? • An alumnus\u27 view of Freeland: Alumnus recalls Freeland as source of campus activities • Search into Ursinus history substantiates second oldest graduate\u27s assertion: Yes, Freeland was indeed everything • Delaware flattens UC: Rivell, Struthers only winners • Bears crush S\u27more; Fall to PMC • Intramural corner • Greek gleaningshttps://digitalcommons.ursinus.edu/weekly/1214/thumbnail.jp

The Ursinus Weekly, November 23, 1964

Write me a murder, a skillful presentation of a weak play • Junior class announces \u27S no ball turnabout • WSGA report on women\u27s programs • Judy Collins to appear in campus folk concert: Performance tickets remain on sale • Ursinus receives $1,500 grant from Sears-Roebuck Foundation • Work camps topic of slide lecture • Debaters prepare for Temple novice tournament • Ursinus students attend Sheraton collegiate council • Human Relations Commission starts tutoring program • SWC abandons Sunday vespers • Editorial: Hats off! • Progress keyword in dining hall construction • Annual college music competition • Spotlight: UC abroad; Student\u27s stay in Stockholm • Letters to the editor • Advice column • U.C. history: The pipe dream • Volleyball league begins • Soccermen split 0-5 and 4-3 • Soccermen finish season with 5-5-1 record • UC drops final game to F&M, 20-6 • Bible fellowship sponsors Paul Little, speaker • Greek gleaningshttps://digitalcommons.ursinus.edu/weekly/1235/thumbnail.jp

The Ursinus Weekly, December 2, 1968

Arts Forum held; 4 foreign students featured on panel • Board OKs student members on committees; Student Senate endorses SFARC resolution • Camino real scheduled for December 6th • Mandrake concert is hit; Rock group shows profit • Editorial: Our play; The larger issue • Letters to the editor • Tradition vs. change • Herberg sees anomic moral crisis; Fun morality termed other directed • SFARC minutes • Opinion: Speaker fails to prove dilemma • Freeland Hall: Don\u27t let it be forgot • Senior looks at Freeland: Can Library replace Freeland\u27s primacy? • Search into history substantiates claim of second oldest graduate that Freeland was everything • Instructor asks what do students really want? • Now is the time to unite • WRUC increases wattage to allow greater service • USGA discusses Black Alliance • Students to decide on two government proposals • Pratt art show opens at Ursinus • PNE Folk Fest held; U.C. talent featured • U.C. sponsors Career Days • Howard honored for achievements • Gurzynski\u27s men win title; Albert leads UC to championship • Soccer team edges LaSalle after losing to Haverford • Flowers win intramural crown with 6-0 victory over Sig Rho • Whatley lauds squad; predicts progress • Bears destroy Haverford; Shuman wins Maxwell Award • All Stars will visit Glassboro • Greek gleaningshttps://digitalcommons.ursinus.edu/weekly/1167/thumbnail.jp

The Transcriptional Repressor dMnt Is a Regulator of Growth in Drosophila melanogaster

The Myc-Max-Mad/Mnt network of transcription factors has been implicated in oncogenesis and the regulation of proliferation in vertebrate cells. The identification of Myc and Max homologs in Drosophila melanogaster has demonstrated a critical role for dMyc in cell growth control. In this report, we identify and characterize the third member of this network, dMnt, the sole fly homolog of the mammalian Mnt and Mad family of transcriptional repressors. dMnt possesses two regions characteristic of Mad and Mnt proteins: a basic helix-loop-helix-zipper domain, through which it dimerizes with dMax to form a sequence-specific DNA binding complex, and a Sin-interacting domain, which mediates interaction with the dSin3 corepressor. Using the upstream activation sequence/GAL4 system, we show that expression of dMnt results in an inhibition of cellular growth and proliferation. Furthermore, we have generated a dMnt null allele, which results in flies with larger cells, increased weight, and decreased life span compared to wild-type flies. Our results demonstrate that dMnt is a transcriptional repressor that regulates D. melanogaster body size