17 research outputs found
Challenges and Opportunities for Wound Field Synchronous Generators in Future More Electric Aircraft
Electrical machines and drives keep moving away from traditional technologies such as brushed machines and wound field machines towards lighter, ‘easier to maintain’ machines. A very interesting aspect is that certain transport applications, especially the aerospace industry, still favour the classical wound field machine for its main generating system such as the Boeing 787. This paper focuses on investigating this particular trend by presenting a detailed overview of historical power generation systems on aircraft. This paper compares the current state of the art of wound field machines with other generator families. The results of this analysis are then projected into the needs of the electrical power generation and distribution system on aircraft. While power density is a major objective for any aerospace application, however the extra benefits associated with wound field systems are still essential in modern aircraft. The paper then focuses on the main challenges for improving power density of wound field machines. Recommendations, opportunities and improvements related to wound field machines are discussed. In conclusion, if robust designs for higher speed wound field generators were consolidated, it would be very probable that these classical machines might still be implemented on future MEA platforms
Interleukin-41: a novel serum marker for the diagnosis of alpha-fetoprotein-negative hepatocellular carcinoma
BackgroundFor the lack of effective serum markers for hepatocellular carcinoma(HCC) diagnosis, it is difficult to detect liver cancer and identify its recurrence early.MethodsDatabases were used to analyze the genes potentially associated with alpha-fetoprotein(AFP). ELISA assay was used to detect the serum IL-41 in HCC, liver metastases, hepatitis, and healthy people. Immunohistochemical staining was used to analyze the relative quantification of IL-41 in HCC and paracancer tissues. Various survival curves were plotted according to clinical pathological data and helped us draw the ROC curve of IL-41 diagnosis of HCC.ResultsThe serum expression of IL-41 was highest in AFP negative HCC patients and significantly higher than that in AFP positive HCC and metastatic cancer patients. There was a significant negative correlation between elevated serum IL-41 and AFP(<1500ng/ml). The clinicopathological features suggested that the serum IL-41 level was significantly correlated with capsule invasion, low differentiation and AFP. High serum expression of IL-41 suggests poorer survival and earlier recurrence after resection, and IL-41 upregulated in patients with early recurrence and death. The expression of IL-41 was higher in HCC tissues of patients with multiple tumors or microvascular invasion. The ROC curve showed that serum IL-41 had a sensitivity of 90.17 for HCC and a sensitivity of 96.63 for AFP-negative HCC, while the specificity was higher than 61%.ConclusionIL-41 in serum and tissue suggests poor prognosis and postoperative recurrence in HCC patients and could be a new serum diagnostic marker for AFP negative patients
Pre-Absorbed Immunoproteomics: A Novel Method for the Detection of Streptococcus suis Surface Proteins
Streptococcus suis serotype 2 (SS2) is a zoonotic pathogen that can cause infections in pigs and humans. Bacterial surface proteins are often investigated as potential vaccine candidates and biomarkers of virulence. In this study, a novel method for identifying bacterial surface proteins is presented, which combines immunoproteomic and immunoserologic techniques. Critical to the success of this new method is an improved procedure for generating two-dimensional electrophoresis gel profiles of S. suis proteins. The S. suis surface proteins identified in this study include muramidase-released protein precursor (MRP) and an ABC transporter protein, while MRP is thought to be one of the main virulence factors in SS2 located on the bacterial surface. Herein, we demonstrate that the ABC transporter protein can bind to HEp-2 cells, which strongly suggests that this protein is located on the bacterial cell surface and may be involved in pathogenesis. An immunofluorescence assay confirmed that the ABC transporter is localized to the bacterial outer surface. This new method may prove to be a useful tool for identifying surface proteins, and aid in the development of new vaccine subunits and disease diagnostics
Soil respiration in cucumber field under crop rotation in solar greenhouse
Crop residues are the primary source of carbon input in the soil carbon pool. Crop rotation can impact the plant biomass returned to the soil, and influence soil respiration. To study the effect of previous crops on soil respiration in cucumber (Cucumis statirus L.) fields in solar greenhouses, soil respiration, plant height, leaf area and yield were measured during the growing season (from the end of Sept to the beginning of Jun the following year) from 2007 to 2010. The cucumber was grown following fallow (CK), kidney bean (KB), cowpea (CP), maize for green manure (MGM), black bean for green manure (BGM), tomato (TM), bok choy (BC). As compared with CK, KB, CP, MGM and BGM may increase soil respiration, while TM and BC may decrease soil respiration at full fruit stage in cucumber fields. Thus attention to the previous crop arrangement is a possible way of mitigating soil respiration in vegetable fields. Plant height, leaf area and yield had similar variation trends under seven previous crop treatments. The ratio of yield to soil respiration revealed that MGM is the crop of choice previous to cucumber when compared with CK, KB, CP, BGM, TM and BC
The Role of Elements Partition and Austenite Grain Size in the Ferrite-Bainite Banding Formation during Hot Rolling
The partitioning and diffusion of solute elements in hot rolling and the effect of the partitioning and diffusion on the ferrite-bainite banding formation after hot rolling in the 20CrMnTi steel were experimentally examined by EPMA (electron probe microanalysis) technology and simulated by DICTRTA and MATLAB software. The austenite grain size related to the hot rolling process and the effect of austenite grain size on the ferrite-bainite banding formation were studied. The results show that experimental steel without banding has the most uniform hardness distribution, which is taken from the edge of the cast slab and 1/4 diameter position of the cast slab, heating at 1100 °C for 2 h and above 1200 °C for 2–4 h during the hot rolling, respectively. Cr, Mn, and Si diffuse and inhomogeneously concentrate in austenite during hot rolling, while C homogeneously concentrates in austenite. After the same hot rolling process, ΔAe3 increases and ferrite-bainite banding intensifies with increasing initial segregation width and segregation coefficient K of solute elements. Under the same initial segregation of solute elements, ΔAe3 drops and ferrite-bainite banding reduces with increasing heating temperature and extension heating time. When ΔAe3 drops below 14 °C, ferrite-bainite banding even disappears. What is more, the austenite grain size increases with increasing heating temperature and extension heating time. When the austenite grain size is above 21 μm, the experimental steel will not appear to have a banded structure after hot rolling
Palaeo-earthquake events during the late Early Palaeozoic in the central Tarim Basin (NW China): evidence from deep drilling cores
Various millimetre-, centimetre- and metre-scale soft-sediment deformation structures (SSDS) have been identified in the Upper Ordovician and Lower-Middle Silurian from deep drilling cores in the Tarim Basin (NW China). These structures include liquefied-sand veins, liquefaction-induced breccias, boudinage-like structures, load and diapir- or flame-like structures, dish and mixed-layer structures, hydroplastic convolutions and seismic unconformities. The deformed layers are intercalated by undeformed layers of varying thicknesses that are petrologically and sedimentologically similar to the deformed layers
Palaeo-earthquake events during the late Early Palaeozoic in the central Tarim Basin (NW China): evidence from deep drilling cores
Various millimetre-, centimetre- and metre-scale soft-sediment deformation structures (SSDS) have been identified in
the Upper Ordovician and Lower-Middle Silurian from deep drilling cores in the Tarim Basin (NW China). These struc -tures include liquefied-sand veins, liquefaction-induced breccias, boudinage-like structures, load and diapir- or flame --like structures, dish and mixed-layer structures, hydroplastic convolutions and seismic unconformities. The deformed
layers are intercalated by undeformed layers of varying thicknesses that are petrologically and sedimentologically
similar to the deformed layers.
The SSDS developed in a shelf environment during the early Late Ordovician and formed initially under shear tensile
stress conditions, as indicated by boudinage-like structures; during the latest Ordovician, SSDS formed under a com -pressional regime. The SSDS in the Lower-Middle Silurian consist mainly of mixed layers and sand veins; they formed
in shoreline and tidal-flat settings with liquefaction features indicating an origin under a compressional stress regime.
By Silurian times, the centre of tectonic activity had shifted to the south-eastern part of the basin.
The SSDS occur at different depths in wells that are close to the syn-sedimentary Tazhong 1 Fault (TZ1F) and associated
reversed-thrust secondary faults. Based on their characteristics, the inferred formation mechanism and the spatial asso -ciation with faults, the SSDS are interpreted as seismites. The Tazhong 1 fault was a seismogenic fault during the later
Ordovician, whereas the reversed-direction secondary faults became active in the Early-Middle Silurian.
Multiple palaeo-earthquake records reflect pulses and cyclicity, which supports secondary tectonic activity within the
main tectonic movement. The range of SSDS structures reflects different developments of tectonic activity with time for
the various tectonic units of the centralbasin. The effects of the strong palaeo-earthquake activity coincide with uplift,
fault activity and syn-tectonic sedimentation in the study area during the Late Ordovician to Middle Silurian
Urban building height extraction accommodating various terrain scenes using ICESat-2/ATLAS data
Although the photon point cloud data acquired from ICESat-2/ATLAS can be efficiently employed in urban building height extraction, its universal applicability in undulating terrain scenarios is constrained, and there are noticeable issues of false positives and false negatives. This research establishes a terrain-adaptive methodological framework based on ICESat-2/ATLAS photon point cloud to extract high-precision, high-density building height data across varied urban topographical conditions. First, a terrain-adaptive elevation buffer is utilized to coarse denoise the photon point cloud, involving the removal of the majority of noise photons in the scene, thereby enhancing the efficiency of subsequent algorithms. Second, urban signal photons are extracted from the remaining original photons using the Adaptive Method Based on Single-Photon Spatial Distribution (SPSD-AM). This approach demonstrates high universality across various urban scenes, while simultaneously ensuring a stable accuracy of urban signal photon extraction. Subsequently, ground photons are extracted from the urban signal photons and fit the ground curve based on the Adaptive Method Based on Spatial Differences of Urban Signal Photons (USPSD-AM), which addresses the challenge of the potential mixing of ground and building photons in complex terrain scenarios. A precise ground curve is then employed to extract building photons from urban signal photons. In order to mitigate issues such as false positives and negatives, post-processing steps, including completion and denoising of building photons, are implemented. Finally, the acquired building photons and ground curve are adopted to extract accurate building height parameters. The precision verification results show that the extracted building heights are considerably consistent with the reference building heights. The mean RMSE and MAE are 0.273Â m and 0.202Â m for flat terrains and 1.168Â m and 0.759Â m for undulating terrains, respectively. The proposed method demonstrates superior applicability across diverse urban scenarios, providing a robust theoretical foundation for large-scale urban building height retrieval efforts