81 research outputs found
Performance of a plastic scintillator developed using styrene monomer polymerization
This paper presents a newly developed plastic scintillator produced in
collaboration with Turkiye Energy, Nuclear and Mineral Research Agency
(TENMAK). The scintillator is manufactured using thermal polymerization of
commercially available styrene monomer. The absorption spectrum of the
scintillator exhibited two absorption bands at 225 nm and 340 nm, with an
absorption edge observed at 410 nm. The wavelength of the emitted light was
measured in the range of 400-800 nm, with a maximum intensity at 427 nm.
Monoenergetic electrons from the 137Cs source were used to evaluate the
characteristics of the new scintillator, particularly its light yield. As the
light readout the MAPD-3NM type silicon photomultiplier array (4 x 4) with an
active area of 15 x 15 mm2, assembled using single MAPDs with an active area of
3.7 x 3.7 mm2, was used. The light yield of the scintillator was determined to
be 6134 photons/MeV. In addition, the efficiency of the scintillator for gamma
rays with an energy of 662 keV was found to be approximately 1.8 %. A CmBe
neutron source was employed to evaluate its fast neutron detection performance.
However, neutron/gamma discrimination using pulse shape discrimination (charge
integration) method was not observed. The results demonstrate the potential of
a newly produced plastic scintillator for various applications, particularly in
radiation monitoring and detection systems.Comment: 7 pages, 7 figure
An example of secondary fault activity along the North Anatolian Fault on the NE Marmara Sea Shelf, NW Turkey
Seismic data on the NE Marmara Sea Shelf indicate that a NNE-SSW-oriented buried basin and ridge system exist on the sub-marine extension of the Paleozoic Rocks delimited by the northern segment of the North Anatolian Fault (NS-NAF), while seismic and multi-beam bathymetric data imply that four NW-SE-oriented strike-slip faults also exist on the shelf area. Seismic data indicate that NW-SE-oriented strike-slip faults are the youngest structures that dissect the basin-ridge system. One of the NW-SE-oriented faults (F1) is aligned with a rupture of the North Anatolian Fault (NAF) cutting the northern slope of the Cinarcik Basin. This observation indicates that these faults have similar characteristics with the NS-NAF along the Marmara Sea. Therefore, they may have a secondary relation to the NAF since the principle deformation zone of the NAF follows the Marmara Trough in that region. The seismic energy recorded on these secondary faults is much less than that on the NAF in the Marmara Sea. These faults may, however, produce a large earthquake in the long term
Genetic Association of a Gain-of-Function IFNGR1 Polymorphism and the Intergenic Region LNCAROD/DKK1 With Behcet's Disease
Objective. Behçet’s disease is a complex systemic inflammatory vasculitis of incompletely understood etiology. This study was undertaken to investigate genetic associations with Behçet’s disease in a diverse multiethnic population.Methods. A total of 9,444 patients and controls from 7 different populations were included in this study. Genotyping was performed using an Infinium ImmunoArray- 24 v.1.0 or v.2.0 BeadChip. Analysis of expression data from stimulated monocytes, and epigenetic and chromatin interaction analyses were performed.Results. We identified 2 novel genetic susceptibility loci for Behçet’s disease, including a risk locus in IFNGR1(rs4896243) (odds ratio [OR] 1.25; P = 2.42 × 10−9) and within the intergenic region LNCAROD/DKK1 (rs1660760) (OR 0.78; P = 2.75 × 10−8). The risk variants in IFNGR1 significantly increased IFNGR1 messenger RNA expression in lipopolysaccharide- stimulated monocytes. In addition, our results replicated the association (P 30 genetic susceptibility loci with a suggestive level of association (P < 5 × 10−5), which will require replication. Finally, functional annotation of genetic susceptibility loci in Behçet’s disease revealed their possible regulatory roles and suggested potential causal genes and molecular mechanisms that could be further investigated.Conclusion. We performed the largest genetic association study in Behçet’s disease to date. Our findings reveal novel putative functional variants associated with the disease and replicate and extend the genetic associations in other loci across multiple ancestries
Dislexia e ensino-aprendizagem de língua portuguesa : um estudo de caso
Monografia (graduação)—Universidade de Brasília, Instituto de Letras, 2013.Esta pesquisa trata da dislexia e do ensino-aprendizagem de Língua Portuguesa para disléxicos, com base em um estudo de caso com estudante disléxico da rede pública de ensino do Plano Piloto. Dentre as questões abordadas, estão as definições da dislexia, seus tipos e possíveis tratamentos, além da discussão do espaço que tal distúrbio de aprendizagem tem na educação, a sugestão de inclusão da dislexia na Educação Especial e, consequentemente, nas salas de recursos e a adequação da metodologia de ensino, baseada na exploração dos gêneros textuais e dos multiletramentos, dentro da perspectiva Sociointeracionista de Vygotsky e da proposta de professor libertador, de Paulo Freire
Acute presentation of autoimmune hepatitis in a patient with myasthenia gravis, thymoma, Hashimoto thyroiditis and connective tissue disorder
Myasthenia gravis is an antibody-mediated autoimmune disease at the neuromuscular junctions. It can be associated with many other autoimmune diseases. We report a case of acute presentation of autoimmune hepatitis with myasthenia gravis, thymoma, Hashimoto thyroiditis and connective tissue disorder. © 2012 The Japan Society of Hepatology
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