2,364 research outputs found

    Scalable Grouping Random Key Predistribution in Large Scale Wireless Sensor Networks

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    [[abstract]]The security issue in a wireless sensor network (WSN) has been drawing considerable research attention in recent years. Key management, a basic security service, becomes the core design for various security services, such as encryption and authentication. To increase the connectivity of each key in a large-scale WSN and to enlarge its maximum supportable network size, this paper presents a scalable grouping (SG) random key predistribution scheme. The SG scheme divides all nodes into several groups and uses the one-way function to generate group-to-group pairwise keys. To improve resilience against node capture, i.e., to fortify the security strength, the scheme takes on the concept that the link key is composed of some shared keys. For any two nodes with two or more shared keys, the SG scheme uses the exclusive-OR operation to compose the link key -- assuring the link key used to secure a link is nearly unique. Experimental results show that the SG scheme is able to generate better resilience against node capture and higher scalability than existing random key based schemes.[[notice]]補正完畢[[incitationindex]]EI[[booktype]]紙

    Childrens Education, Intergenerational Support, And Elderly Parents Health in Taiwan

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    This study uses longitudinal data to examine how adult children's education and support patterns affect their elderly parents' health transitions in Taiwan, after controlling for various socioeconomic characteristics of the elderly. Although we are unable to completely eliminate the possibility of reverse causal influences or selectivity, we find evidence that adult children's education promotes good health among their elderly parents. The mean years of adult children's schooling decrease the incidence of disability among the functionally independent elderly at the baseline, and enhance recovery from disability among the disabled elderly at the baseline for the six-year interval that followed. Data suggest that these effects are created mainly when children share their nonmaterial resources, including knowledge about health and health care systems. We speculate that this association between children's education and elderly health is unique to social contexts with a tradition of extended family systems and current rapid economic growth; however this hypothesis needs further tests in diverse social contexts

    Quantitative Mechanical Properties of the Relaxed Biceps and Triceps Brachii Muscles in Patients with Subacute Stroke: A Reliability Study of the Myoton-3 Myometer

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    Objective. Test-retest reliability of the myotonometer was investigated in patients with subacute stroke. Methods. Twelve patients with substroke (3 to 9 months poststroke) were examined in standardized testing position twice, 60 minutes apart, with the Myoton-3 myometer to measure tone, elasticity, and stiffness of relaxed bilateral biceps and triceps brachii muscles. Intrarater reliability of muscle properties was determined using intraclass correlation coefficient (ICC), the standard error of measurement (SEM), and the minimal detectable change (MDC). Results. Intrarater reliability of muscle properties of bilateral biceps and triceps brachii muscles were good (ICCs = 0.79–0.96) except for unaffected biceps tone (ICC = 0.72). The SEM and MDC of bilateral biceps and triceps brachii muscles indicated small measurement error (SEM% <10%, MDC% <25%). Conclusion. The Myoton-3 myometer is a reliable tool for quantifying muscle tone, elasticity, and stiffness of the biceps and triceps brachii in patients with subacute stroke

    Technetium-99m-Labeled Autologous Serum Albumin: A Personal-Exclusive Source of Serum Component

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    Technetium-99m human serum albumin (99mTc-HSA) is an important radiopharmaceutical required in nuclear medicine studies. However, the risk of transfusion-transmitted infection remains a major safety concern. Autopreparation of serum component acquired from patient provides a “personal-exclusive” source for radiolabeling. This paper is to evaluate the practicality of on-site elusion and subsequent radiolabeling efficacy for serum albumin. Results showed that the autologous elute contained more albumin fraction than serum without extraction procedure. Good radiochemical purity and stability were demonstrated after radiolabeling. Biodistribution study showed that labeled albumin accumulated immediately in the lung, liver, and kidney. It was cleared steadily and excreted in the urine. The biologic half-life was defined, and all samples passed the pyrogenicity and sterility tests. In conclusion, autoalbumin could be extracted and radiolabeled properly in a nuclear medicine setting. Moreover, the risk of transfusion-transmitted infection associated with nonautologous, multisource 99mTc-HSA agents can be reduced

    Motor neuron-derived Thsd7a is essential for zebrafish vascular development via the Notch-dll4 signaling pathway.

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    BackgroundDevelopment of neural and vascular systems displays astonishing similarities among vertebrates. This parallelism is under a precise control of complex guidance signals and neurovascular interactions. Previously, our group identified a highly conserved neural protein called thrombospondin type I domain containing 7A (THSD7A). Soluble THSD7A promoted and guided endothelial cell migration, tube formation and sprouting. In addition, we showed that thsd7a could be detected in the nervous system and was required for intersegmental vessels (ISV) patterning during zebrafish development. However, the exact origin of THSD7A and its effect on neurovascular interaction remains unclear.ResultsIn this study, we discovered that zebrafish thsd7a was expressed in the primary motor neurons. Knockdown of Thsd7a disrupted normal primary motor neuron formation and ISV sprouting in the Tg(kdr:EGFP/mnx1:TagRFP) double transgenic zebrafish. Interestingly, we found that Thsd7a morphants displayed distinct phenotypes that are very similar to the loss of Notch-delta like 4 (dll4) signaling. Transcript profiling further revealed that expression levels of notch1b and its downstream targets, vegfr2/3 and nrarpb, were down-regulated in the Thsd7a morphants. These data supported that zebrafish Thsd7a could regulate angiogenic sprouting via Notch-dll4 signaling during development.ConclusionsOur results suggested that motor neuron-derived Thsd7a plays a significant role in neurovascular interactions. Thsd7a could regulate ISV angiogenesis via Notch-dll4 signaling. Thus, Thsd7a is a potent angioneurin involved in the development of both neural and vascular systems

    Incidence and recurrence of acute otitis media in Taiwan's pediatric population

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    OBJECTIVE: To report the incidence and recurrence of acute otitis media (AOM) in Taiwan's pediatric population. METHODS: Information from children (aged <= 12 years) with a diagnosis of AOM was retrieved from the 2006 National Healthcare Insurance claims database. We calculated the cumulative incidence rate and the incidence density rate of recurrent AOM within one year after the initial diagnosis in 2006. We used a multivariate logistic regression model to assess the predictors for recurrence of AOM. RESULTS: The annual incidence rate of AOM was estimated to be 64.5 cases per 1,000 children. The overall one-year cumulative incidence rate of recurrence was 33.1%, and the incidence density rate was 33.5 cases per 100 personyears, with the highest figure (41.2 cases per 100 person-years) noted for children aged 0-2 years. Recurrence was significantly associated with age, gender, place of treatment, and physician specialty. CONCLUSION: AOM remains a major threat to children's health in Taiwan. Male children and very young children require more aggressive preventive strategies to reduce the risk of recurrence
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