Evaluation of shear bond strength of a composite resin to white mineral trioxide aggregate with three different bonding systemsa: an in vitro analysis

Background: Mineral trioxide aggregate (MTA) is a biomaterial that has been investigated for endodontic applications. With the increased use of MTA in pulp capping, pulpotomy, perforation repair, apexification and obturation, the material that would be placed over MTA as a final restoration is an important matter. As composite resins are one of the most widely used final restorative materials, this study was conducted to evaluate the shear bond strength of a composite resin to white mineral trioxide aggregate (WMTA) using three different bonding systems namely the two-step etch and rinse adhesive, the self-etching primer and the All-in-one system. Material and Methods: Forty five specimens of white MTA (Angelus) were prepared and randomly divided into three groups of 15 specimens each depending on the bonding systems used respectively. In Group A, a Two-step etch and rinse adhesive or ‘total-etch adhesive’, Adper Single Bond 2 (3M/ESPE) and Filtek Z350 (3M ESPE, St Paul, MN) were placed over WMTA. In group B, a Two-step self-etching primer system, Clearfil SE Bond (Kuraray, Medical Inc) and Filtek Z350 were used. In Group C, an All-in-one system, G Bond (GC corporation, Tokyo, Japan) and Filtek Z350 were used. The shear bond strength was measured for all the specimens. The data obtained was subjected to One way Analysis of Variance (ANOVA) and Scheffe’s post hoc test. Results: The results suggested that the Two-step etch and rinse adhesive when used to bond a composite resin to white MTA gave better bond strength values and the All-in-one exhibited the least bond strength values. Conclusions: The placement of composite used with a Two-step etch and rinse adhesive over WMTA as a final restoration may be appropriate

Management of a permanent maxillary first molar with two disto buccal canals with the aid of spiral computed tomography: a case report

Human molars show considerable anatomic variations with respect to number of roots and root canals. The most common form of the permanent maxillary first molar has three roots and four canals, two mesiobuccal canals and one distobuccal and palatal canal each. 98.3% of maxillary first molar have been reported to have a single distobuccal canal. Two canals were found only 1.7% of the time, hence showing the second disto buccal canal to being a rare occurrence. Conventionally radiographs are used to determine root canal anatomy, which is a 2- dimensional representation of a 3-dimensional object. Diagnostic methods like spiral computerized tomography where a 3 dimensional data is acquired are useful to determine complex morphology. This case report presents the management of a maxillary first molar with two disto buccal root canals confirmed with the aid of computed tomography along with the conventional radiographic method. Computed Tomography scan slices revealed two separate distobuccal canals at the coronal 3rd of the root. The second distobuccal canal was missing in the middle and apical 3rd indicating; it might have joined the distobuccal canal at the middle 3rd area

Extended long-segment Hirschsprungs’ disease in the Waardenburg–Shah syndrome

Hypopigmentation, either a white forelock or changes in the eyebrows and/or isochromia irides, associated with signs of bowel obstruction should alert the paediatrician and paediatric surgeons to the possibility of aganglionosis. We report a case of Waardenburg–Shah syndrome, which is a very rare congenital disorder with variable clinical expression, characterized by Hirschsprungs’ disease and abnormal melanocyte migration, resulting in pigmentary abnormalities and sensorineural deafness. Our patient had an exceptional association of extended long-segment aganglionosis and underwent a proximal ileostomy but did not survive until a definitive procedure was performed. Long-term prognosis of such children is associated with high morbidity and mortality. Keywords: extended long-segment Hirschsprungs’ disease, Waardenburg–Shah Syndrome, white foreloc

Antenatal dexamethasone for early preterm birth in low-resource countries

BACKGROUND: The safety and efficacy of antenatal glucocorticoids in women in low-resource countries who are at risk for preterm birth are uncertain. METHODS: We conducted a multicountry, randomized trial involving pregnant women between 26 weeks 0 days and 33 weeks 6 days of gestation who were at risk for preterm birth. The participants were assigned to intramuscular dexamethasone or identical placebo. The primary outcomes were neonatal death alone, stillbirth or neonatal death, and possible maternal bacterial infection; neonatal death alone and stillbirth or neonatal death were evaluated with superiority analyses, and possible maternal bacterial infection was evaluated with a noninferiority analysis with the use of a prespecified margin of 1.25 on the relative scale. RESULTS: A total of 2852 women (and their 3070 fetuses) from 29 secondary- and tertiary-level hospitals across Bangladesh, India, Kenya, Nigeria, and Pakistan underwent randomization. The trial was stopped for benefit at the second interim analysis. Neonatal death occurred in 278 of 1417 infants (19.6%) in the dexamethasone group and in 331 of 1406 infants (23.5%) in the placebo group (relative risk, 0.84; 95% confidence interval [CI], 0.72 to 0.97; P=0.03). Stillbirth or neonatal death occurred in 393 of 1532 fetuses and infants (25.7%) and in 444 of 1519 fetuses and infants (29.2%), respectively (relative risk, 0.88; 95% CI, 0.78 to 0.99; P=0.04); the incidence of possible maternal bacterial infection was 4.8% and 6.3%, respectively (relative risk, 0.76; 95% CI, 0.56 to 1.03). There was no significant between-group difference in the incidence of adverse events. CONCLUSIONS: Among women in low-resource countries who were at risk for early preterm birth, the use of dexamethasone resulted in significantly lower risks of neonatal death alone and stillbirth or neonatal death than the use of placebo, without an increase in the incidence of possible maternal bacterial infection.Fil: Oladapo, Olufemi T.. Organizacion Mundial de la Salud; ArgentinaFil: Vogel, Joshua P.. Organizacion Mundial de la Salud; ArgentinaFil: Piaggio, Gilda. Organizacion Mundial de la Salud; ArgentinaFil: Nguyen, My-Huong. Organizacion Mundial de la Salud; ArgentinaFil: Althabe, Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; ArgentinaFil: Metin Gülmezoglu, A.. Organizacion Mundial de la Salud; ArgentinaFil: Bahl, Rajiv. Organizacion Mundial de la Salud; ArgentinaFil: Rao, Suman P.N.. Organizacion Mundial de la Salud; ArgentinaFil: de Costa, Ayesha. Organizacion Mundial de la Salud; ArgentinaFil: Gupta, Shuchita. Organizacion Mundial de la Salud; ArgentinaFil: Shahidullah, Mohammod. No especifíca;Fil: Chowdhury, Saleha B.. No especifíca;Fil: Ara, Gulshan. No especifíca;Fil: Akter, Shaheen. No especifíca;Fil: Akhter, Nasreen. No especifíca;Fil: Dey, Probhat R.. No especifíca;Fil: Abdus Sabur, M.. No especifíca;Fil: Azad, Mohammad T.. No especifíca;Fil: Choudhury, Shahana F.. No especifíca;Fil: Matin, M.A.. No especifíca;Fil: Goudar, Shivaprasad S.. No especifíca;Fil: Dhaded, Sangappa M.. No especifíca;Fil: Metgud, Mrityunjay C.. No especifíca;Fil: Pujar, Yeshita V.. No especifíca;Fil: Somannavar, Manjunath S.. No especifíca;Fil: Vernekar, Sunil S.. No especifíca;Fil: Herekar, Veena R.. No especifíca;Fil: Bidri, Shailaja R.. No especifíca;Fil: Mathapati, Sangamesh S.. No especifíca;Fil: Patil, Preeti G.. No especifíca;Fil: Patil, Mallanagouda M.. No especifíca;Fil: Gudadinni, Muttappa R.. No especifíca;Fil: Bijapure, Hidaytullah R.. No especifíca;Fil: Mallapur, Ashalata A.. No especifíca;Fil: Katageri, Geetanjali M.. No especifíca;Fil: Chikkamath, Sumangala B.. No especifíca;Fil: Yelamali, Bhuvaneshwari C.. No especifíca;Fil: Pol, Ramesh R.. No especifíca;Fil: Misra, Sujata S.. No especifíca;Fil: Das, Leena. No especifíca

Study on correlation of Serum ferritin levels with serum calcium, phosphate and parathormone levels in patients with β-thalassemia major receiving blood transfusion

Introduction:Thalassemia is a heterogeneous family of inherited disorders of hemoglobin synthesis. The combination of transfusion and chelation therapy has dramatically extended the life expectancy of thalassemia patients, but with complications like hypocalcaemia. The present study was undertaken to estimate serum calcium, phosphate and parathormone levels in patients with β- thalassemia who are receiving repeated blood transfusion and to correlate them with serum ferritin levels.Method:Hospital based study conducted at S. Nijalingappa Medical College and Hanagal Shri Kumareshwar hospital, Bagalkot. The study period was from 2015 to 2016. During study period, 53 beta thalassemia major cases were fulfilling inclusion criteria were investigated. Serum calcium level was determined  by  OCPC  method,  serum  phosphate  levels  by  ammonium  molybdate method. And chemiluminescent immunoassay (CLIA) method used to estimate the parathormone levels.Result:The study consisted of 32 (60.4%) males and 21 (39.6%) females. Among 53 transfusion dependent children studied, the mean age is 5.249 years.  There is a negative correlation between serum ferritin and serum calcium as well as, parathyroid hormone which is statistically significant (p value <0.005).There is a positive correlation between serum ferritin  and  serum  phosphate  and  ALP  which  is  statistically significant  (p <0.005).Conclusion: Thalassemia  is  a  genetic  disorder,  which  should  be  diagnosed  as  early  as possible, regular blood transfusion in order to sustain a good growth and prevent stunting

Modelling and simulation of hybrid technology in vehicles

This study focuses on the performance results obtained from comparing two variants of naturally aspirated petrol engines to a petrol engine with hybrid electric assist using MATLAB Driveline. The comparative study analyses the power output obtained from the simulations. The new era of hybrid electric technology can provide performance comparable to naturally aspirated engines is the main focus of this paper