36 research outputs found

    A Distributed Synchronisation-based Predictor for Lur'e-type Nonlinear Systems

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    This paper proposes a distributed state predictor for nonlinear systems using sampled measured data. In particular, we attempt to develop a distributed state predictor for Lur'e systems based on anticipating synchronisation. Anticipating synchronisation is a leader-follower synchronisation such that the follower system synchronises with the future values of the leader system by using delayed feedback. Since the prediction scheme has a closed-loop structure, it is expected to have robustness for disturbance and model mismatch. In this paper, we develop a distributed predictor that consists of networks of multiple predictors based on anticipatory synchronisation to achieve the state prediction for sampled-data nonlinear systems. First, we consider a distributed state predictor in the case where all measurements are sampled synchronously. After that, we develop a distributed state predictor based on asynchronously acquired measurements. The validity of the obtained results is illustrated in a numerical example

    A Distributed Synchronisation-based Predictor for Lur'e-type Nonlinear Systems

    Get PDF
    This paper proposes a distributed state predictor for nonlinear systems using sampled measured data. In particular, we attempt to develop a distributed state predictor for Lur'e systems based on anticipating synchronisation. Anticipating synchronisation is a leader-follower synchronisation such that the follower system synchronises with the future values of the leader system by using delayed feedback. Since the prediction scheme has a closed-loop structure, it is expected to have robustness for disturbance and model mismatch. In this paper, we develop a distributed predictor that consists of networks of multiple predictors based on anticipatory synchronisation to achieve the state prediction for sampled-data nonlinear systems. First, we consider a distributed state predictor in the case where all measurements are sampled synchronously. After that, we develop a distributed state predictor based on asynchronously acquired measurements. The validity of the obtained results is illustrated in a numerical example

    Molekularna dijagnostika i serološka istraživanja pestivirusa u ovaca.

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    In this research, the virological and serological presence of pestiviruses, such as border disease virus (BDV) was investigated in a sheep in the Central and Eastern Black Sea Regions of Turkey. The study material consisted of 40 organ materials collected from 13 aborted lambs, which were suspected to have pestiviruses, BDV and Bovine Viral Diarrhoea Virus (BVDV). Viral nucleic acids were investigated by using the reverse transcription polymerase chain reaction (RT-PCR). Nine of 13 aborted lambs (69.2%) and 24 of 40 organ samples (60%) obtained from those sheep were BDV RNA positive, whilst all the animals and organ samples were BVDV-RNA negative. Serum samples collected from 401 randomly selected sheep were investigated for pestivirus antibodies using competitive ELISA (cELISA) and the serum microneutralisation test (SNT) using BVDV-NADL strain. Seropositivity was found in between 7.22 and 74.38% with cELISA and 4.81 and 67.76% with SNT. Seropositivity rates in Amasya and Tokat provinces were higher than in Samsun and Giresun. The obtained data indicated that pestivirus infection in sheep is widespread in the Central and Eastern Black Sea Region.U radu su prikazana virološka i serološka istraživanja pestivirusa odnosno borderske bolesti u ovaca na središnjem i istočnom području Crnoga mora u Turskoj. Ukupno je bilo pretraženo 40 uzoraka tkiva različitih organa uzetih od 13 pobačenih plodova pod sumnjom da je uzročnik bio virus borderske bolesti ili virus virusnog proljeva goveda. Uzorci su bili pretraženi na prisutnost virusne nukleinske kiseline lančanom reakcijom polimerazom uz prethodnu reverznu transkripciju (RT-PCR). Devet od 13 pobačenih plodova (69,2%) i 24 od 40 uzoraka tkiva organa (60%) sadržavalo je RNA virusa borderske bolesti. Svi pretraženi uzorci bili su negativni na virus virusnoga proljeva. Uzorci seruma nasumce prikupljeni od 401 ovce bili su pretraženi na prisutnost specifičnih protutijela uporabom kompetitivnoga imunoenzimnoga testa (cELISA) i serum neutralizacijskoga testa (SNT) sa sojem NADL virusa virusnoga proljeva goveda. Ustanovljeno je da sepostotak serološki pozitivnih cELISA-om kretao od 7,22 do 74,38%, a SNT-om od 4,81 do 67,76%. Postotak serološki pozitivnih životinja u provincijama Amasya i Tokat bio je veći nego u provincijama Samsun i Giresun. Rezultati upućuju na zaključak da su pestivirusne zaraze rasprostranjene u ovaca na središnjem i istočnom području Crnoga mora

    Seroprevalencija goveđeg herpevirusa 1 u ovaca u Turskoj.

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    In the present study, sera from 1146 sheep from eight different locations in the northern provinces of Turkey were investigated against bovine herpesvirus type 1 (BHV-1) by a conventional method, as serum neutralization. Prevalence of antibodies detected against BHV-1 in sheep was found to be 1.74% (20/1146). Serum samples obtained from sheep from 4 different provinces were detected negative against BHV-1. As a result, with this study presence of BHV-1 was detected for the first time in sheep in the northern provinces of Turkey.Uzorci seruma 1146 ovaca s osam različitih mjesta u sjevernom području Turske bili su pretraženi na goveđi herpesvirus 1 (GHV-1) uobičajenim serum neutralizacijskim testom. Specifična protutijela za GHV-1 dokazana su u 1,74% (20/1146) ovaca. Protutijela za GHV-1 nisu bila dokazana u uzorcima uzetima od ovaca u četirima područjima. Time je prvi put dokazana zaraza tim virusom u ovaca u sjevernim provincijama Turske

    Prevalencija triju virusa medonosne pčele u Turskoj

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    In this study, 10 worker bees from each of 28 different apiaries were collected (a total of 280 honey bees) from 6 provinces of the Black Sea region in Turkey. These samples were tested by Reverse-Transcriptase PCR (RT-PCR), for three honey bee viruses: acute bee paralysis virus (ABPV), chronic bee paralysis virus (CBPV) and black queen cell virus (BQCV). In addition, the samples were microscopically examined for Varroa destructor. In conclusion, CBPV, BQCV and Varroa destructor were identified in 25%, 21.42% and 53.57% of the bees respectively, but ABPV could not be detected in apiaries. This is the first report of CBPV, BQCV in Turkey.Prikupljeno je po 10 radilica s 28 različitih pčelinjaka u šest provincija na području oko Crnoga mora u Turskoj. Uzorci su bili pretraženi lančanom reakcijom polimerazom uz prethodnu reverznu transkripciju (RTPCR) na tri virusa medonosne pčele: virus akutne pčelinje paralize, virus kronične pčelinje paralize i virus crnih matičnjaka. Uzorci su povrh toga bili pretraženi na prisutnost parazita Varroa destructor. Virus kronične paralize bio je ustanovljen u 25%, virus crnih matičnjaka u 21,4% i Varroa destructor u 53,57% pčela dok virus akutne pčelinje paralize nije bio dokazan. Ovo je prvi dokaz prisutnosti virusa kronične pčelinje paralize i virusa crnih matičnjaka u Turskoj

    Biochemical Characterisation and Sensory Evaluation of Differently Coloured and Shaped Tomato Cultivars

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    Antioxidant capacity, total phenolic content, colour, sugar, volatiles, ascorbic acid and carotenoid (β-carotene and lycopene) contents of differently coloured and shaped tomato cultivars (cvs) grown in the Eastern Mediterranean region, Turkey were determined, along with a sensory evaluation. Tomato cultivars of two different types (cherry and beefsteak) and four different colours (red, yellow, orange and brown) were analysed. All plants were simultaneously grown in the same field and subjected to identical horticultural practices to minimise the effects of environmental conditions and to maximise those related to genotype. The red cherry cultivar had the highest lycopene content, while the orange beefsteak cultivar had the highest β-carotene content. The highest antioxidant capacity, total phenolic content and hardness scores were found in cherry-type tomatoes, except the yellow one. The red cherry cultivar had the highest sugar content. Red and brown cherry cultivars were also significant in terms of their high carotenoid and sugar contents, along with a high antioxidant activity. The brown cherry cultivar had the highest total phenol content. The highest quantities of 2-hexenal, 3-hexen-1-ol, and 6-methyl-5-hepten-2-one were detected in red cultivars. The brown cherry cultivar had the highest sweetness, typical aroma and hardness scores, while the yellow beefsteak cultivars the lowest sweetness typical aroma scores. In terms of sensory parameters, red and brown cultivars scored higher than yellow and orange ones

    Characterisation of the First Bovine Parainfluenza Virus 3 Isolate Detected in Cattle in Turkey

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    A respiratory disease outbreak on a cattle farm in northern Turkey produced respiratory tract symptoms and severe pneumonia symptoms in 20 calves. Eight calves died, and a lung specimen from one carcass was analysed for bacteria and for viruses of the Bovine respiratory diseases complex. Bacteriological analysis was negative, but antigen detection ELISA and RT-PCR results indicated the presence of Bovine parainfluenza virus (BPIV). Virus isolation succeeded on Madin-Darby Bovine Kidney cells, and subsequent whole genome sequencing and phylogenetic analysis identified BPIV-3c. This is the first report of BPIV-3c isolation from cattle in Turkey, indicating the need for more virological and epidemiological studies

    Is SARS-CoV-2 Neutralized More Effectively by IgM and IgA than IgG Having the Same Fab Region?

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    Recently, recombinant monoclonal antibodies (mAbs) of three Ig isotypes (IgG, IgA, and IgM) sharing the same anti-spike protein Fab region were developed; we evaluated their neutralizing abilities using a pseudo-typed lentivirus coated with the SARS-CoV-2 spike protein and ACE2-transfected Crandell–Rees feline kidney cells as the host cell line. Although each of the anti-SARS-CoV-2 mAbs was able to neutralize the spike-coated lentiviruses, IgM and IgA neutralized the viral particles at 225-fold and 125-fold lower concentrations, respectively, than that of IgG. Our finding that the neutralization ability of Igs with the same Fab domain was dramatically higher for IgM and IgA than IgG mAbs suggests a strategy for developing effective and affordable antibody therapies for COVID-19. The efficient neutralization conferred by IgM and IgA mAbs can be explained by their capacity to bind multiple virions. While several IgG mAbs have been approved as therapeutics by the FDA, there are currently no IgM or IgA mAbs available. We suggest that mAbs with multiple antigen-binding sites such as IgM and IgA could be developed as the new generation of therapy

    Simultaneous Reconstruction of Medial Canthal Area and Both Eyelids With a Single Transverse Split Forehead Island Flap

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    WOS: 000286195600087PubMed: 21239938In this report, we are presenting a case in which we have split the paramedian forehead flap, thus providing 2 axially perfused skin flaps for simultaneous reconstruction of the upper and lower lid structures after resection of basal cell carcinoma from the left medial canthal area. We found that split forehead flap seems to be a favorable option for simultaneous reconstruction of the upper and lower eyelid defects by enabling nicely vascularized and abundant amount of regional skin

    Interferon therapy in rheumatic diseases: state-of-the-art 2010

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