The Hemostatic Efficacy of Hydrogen Peroxide Irrigation to Control Intraoperative Bleeding in Adenoidectomy

Objective:Although adenoidectomy is generally accepted as a safe procedure, intraoperative hemorrhage is still the most common and potentially life- threating complication, especially in pediatric patients. We evaluated the clinical effect of intraoperative hydrogen peroxide irrigation with respect to hemostasis and operation times in pediatric adenoidectomy.Methods:This was a prospective, randomized, double- blind study to investigate hydrogen peroxide solution in hemostasis in pediatric patients undergoing adenoidectomy. The patient, the surgeon, and the study nurse were blinded to the surgical technique used.Results:One hundred seventeen (56 males and 61 females) consecutive pediatric patients with a mean age of 5.46±1.19 years were included in the study. There were 58 patients in the hydrogen peroxide group (median age: 6 years, mean age: 5.62±1.28 years) and 59 patients in the control group (median age: 5 years, mean age: 5.31±1.07 years). No significant difference was observed between the two groups with respect to age (p=0.151), gender (p=0.646), or adenoid size (p=0.767). On the other hand, the difference between the groups with respect to operation and hemostasis times was found to be statistically significant (p<0.001 for both). The average operation times were 8.67±0.48 min in the hydrogen peroxide group and 12.30±0.69 min in the control group. The average hemostasis times were 3.67±0.27 min in the hydrogen peroxide group and 5.73±0.31 min in the control group.Conclusion:Hydrogen peroxide solution can be effectively used in adenoidectomy for reducing intraoperative blood loss and for economic benefits

The effect of q-RT-PCR analysis method on saline gargle samples in SARS-CoV-2 clinical diagnostic methods

COVID-19 is a devastating disease, and its control is difficult due to its high transmissibility rate and a long incubation average period (6.4 days). Additionally, more than half of the infected patients were asymptomatic young people or children. The asymptomatic virus transmission is the actual challenge to controlling the disease. Because of limited treatment options, diagnosis techniques have been the first focus all over the world, involving q-RT-PCR as a gold standard, serological tests, point of care studies, or RT-LAMP. Generally, nasopharyngeal, and oropharyngeal samples are preferred clinically as sources. However, alternative sources are being researched, particularly for healthcare professionals who have difficulty taking samples, patients who are afraid of giving samples, and pediatric patients. Herein, physiological saline has been utilized to offer an alternative source besides the swab samples for use in q-RT-PCR. In this study, 212 randomly chosen patients' samples were studied, and we evaluated the concordance and accurate q-RT-PCR results in two different sources, obtained from swab and gargle samples of patients. Herein, physiological saline is utilized, which is widely used medically as a recommended irrigating and wound dressing solution. We obtained in our experiments with this method, the confidence interval determines 74.50% positivity when compared to the routine q-RT-PCR procedure as summarized. In addition, when only the gargle sampling method is studied in low-income countries, the cost of testing for COVID-19 will decrease significantly. Because this method does not require vNAT or VTM transport solution sterile swab sticks as shown. The plastic container with a lid in which the patient can gargle with SF and spit it out is an ideal method for this. Additionally, it provides a great cost-benefit in low-income countries.Private Viromed Istanbul Central Laboratory; Imaging Center, Istanbul, TurkeyThis study was supported by the Private Viromed Istanbul Central Laboratory and Imaging Center, Istanbul, Turkey

Cepstral Peak Point Analyses of Patients Recovering from Supraglottic Laryngectomy

Objective:The aim of this study is to evaluate smoothed cepstral peak point and laryngostrobosopic results in patients who underwent supraglottic laryngectomy.Method:Ten patients who underwent transcervical supraglottic laryngectomy with bilateral modified radical neck dissection, and who completed at least 12 months of follow-up, were included. All patients underwent laryngostroboscopic evaluation at study commencement; glottal closure and mucosal wave pattern were examined. Voice records were taken at fundamental frequency and smoothed cepstral peak point were analysed. Voice handicap index-10 was requested to be completed. Ten healthy individual constituted control group. Results were compared.Results:The mean smoothed cepstral peak points were 1.53-5.91 in the supraglottic laryngectomy group and 4.6-6.06 in controls, a significant difference. The fundamental frequency ranged from 174.49 to 197.25 Hz in the supraglottic laryngectomy group and from 118.57 to 197.61 Hz in the control group, also a significant difference. Laryngostroboscopic evaluation revealed no significant between-group differences in closure, but the mucosal waves differed significantly. Voice handicap index was significantly lower in supraglottic laryngectomy patients.Conclusion:Supraglottic laryngectomy reduces smoothed cepstral peak point and affects the mucosal wave, reducing voice quality

Dobrava Hantavirus Infection Complicated by Panhypopituitarism, Istanbul, Turkey, 2010

We identified Dobrava-Belgrade virus infection in Turkey (from a strain related to hantavirus strains from nearby countries) in a patient who had severe symptoms leading to panhypopituitarism, but no known risk for hantavirus. Our findings emphasize the need for increased awareness of hantaviruses in the region and assessment of symptomatic persons without known risk factors for infection

TRANSFERENCIA DE POSESIONES Y LA VIOLACIÓN DEL ORDENAMIENTO JURÍDICO EN LA COMUNIDAD CAMPESINA DE MALCONGA, ANEXO SARIAPAMPA, DISTRITO DE AMARILIS 2012-2014

TesisEl objetivo principal de la presente investigación es analizar detalladamente los procesos, las condiciones y los mecanismos según los cuales al interior de la Comunidad Campesina Malconga, Anexo Sariapampa se realizan las transferencias de terrenos comunales y su influencia en el desarrollo social y económico de la misma, para lo cual se analizará si ejercen los derechos de propiedad sobre el recurso tierra, y cuan beneficiario ha sido la titulación de la comunidad desde la perspectiva del pluralismo jurídico. Se ha tomado como base de estudio el carácter exploratorio referente al tema, no he encontrado suficiente bibliografía que pudiese guiarme con mayor exactitud y seguridad sobre las transferencias en terrenos comunales, por lo que opte en formular algunas preguntas que pudiesen guiarme en la presente investigación, el tema se desarrolla en un Anexo (Sariapampa) pertenecientes a la Comunidad Campesina de Malconga. Tocando varios criterios que tuviesen los distintos tipos de tierras como vivienda, cultivo, pastos, ganadería entre otros; diferentes niveles de integración al mercado y diferentes niveles de vinculación con instituciones financieras lo cual conllevarían a un desarrollo social y económico óptimo para los Comuneros. Con relación a estos criterios, las hipótesis subyacentes eran que los derechos de los comuneros después de la titulación eran estándar y por la magnitud de tierras la responsabilidad era variable; que cuanto más intensamente vinculada al mercado y a instituciones del estado estaba el comunero, los derechos familiares sobre la tierra serían más importantes que los de la comunidad como tal, y viceversa, a menos mercado, más control comunal sobre las tierras. En efecto, en el Perú, hay una marcada inadecuación de la legislación jurídica a una realidad tan distinta referente a Comunidades Campesinas. No hay una norma que defina como los Comuneros pueden transferir sus tierras y menos conocen sus límites individuales ya que cuentan con un título comunal en conjunto. Las regulaciones de las leyes y reglamentos cuentan con vacíos jurídicos o se aplican normas que poco tienen que ver con la realidad actual pero que finalmente rigen