Josephson effect in a multi-orbital model for Sr2_{2}RuO4_{4}

We study Josephson current between s-wave/spin-triplet superconductor junctions by taking into account details of band structures in Sr$_{2}$RuO$_{4}$ such as three conduction bands, spin-orbit interaction in the bulk and that at the interface. We assume five superconducting order parameters in Sr$_{2}$RuO$_{4}$: a chiral p-wave symmetry and four helical p-wave symmetries. We calculate current-phase relationship $I(\varphi)$ in these junctions, where $\varphi$ is the macroscopic phase difference between two superconductors. The results for a chiral p-wave pairing symmetry show that $\cos(\varphi)$ term appears in the current-phase relation due to time-reversal symmetry (TRS) breaking. On the other hand, $\cos(\varphi)$ term is absent in the helical pairing states which preserve the TRS. We also study the dependence of maximum Josephson current $I_c$ on an external magnetic flux $\Phi$ in a corner junction. The calculated results of $I_c(\Phi)$ show a relation $I_{c}(\Phi) \neq I_{c}(-\Phi)$ in a chiral state and $I_{c}(\Phi)=I_{c}(-\Phi)$ in a helical state. We calculate $I_c(\Phi)$ in a corner and a symmetric SQUIDs geometry. In a symmetric SQUID geometry, the relation $I_{c}(\Phi)=I_{c}(-\Phi)$ is satisfied for all the pairing states and it is impossible to distinguish chiral state from helical one. On the other hand, results for a corner SQUID always show $I_{c}(\Phi) \neq I_{c}(-\Phi)$ and $I_{c}(\Phi)=I_{c}(-\Phi)$ for a chiral and a helical states, respectively. Experimental tests of these relations in a corner junctions and SQUIDs may serve as a tool for unambiguous determination of the pairing symmetry in Sr$_{2}$RuO$_{4}$

CMB Fluctuations and String Compactification Scales

We propose a mechanism for the generation of temperature fluctuations of cosmic microwave background. We consider a large number of fields, such as Kaluza-Klein modes and string excitations. Each field contributes to the gravitational potential by a small amount, but an observable level of temperature fluctuations is achieved by summing up the contribution of typically of order 10^{14} fields. Tensor fluctuations are hardly affected by these fields. Our mechanism is based on purely quantum effects, and is different from the "slow-roll" or "curvaton" scenario. Using the observed data, we find constraints on the parameters of this model, such as the size of the extra dimensions and the string scale. Our model predicts a particular pattern of non-gaussianity with a small magnitude.Comment: 4 pages, 2 figures; v2: Corrected a mistake in eq. (11), which does not affect the subsequent context. Added a comment on inflaton fluctuations at the end of the paper. Final version to appear in Phys. Lett.

Heme and non-heme iron transporters in non-polarized and polarized cells

<p>Abstract</p> <p>Background</p> <p>Heme and non-heme iron from diet, and recycled iron from hemoglobin are important products of the synthesis of iron-containing molecules. In excess, iron is potentially toxic because it can produce reactive oxygen species through the Fenton reaction. Humans can absorb, transport, store, and recycle iron without an excretory system to remove excess iron. Two candidate heme transporters and two iron transporters have been reported thus far. Heme incorporated into cells is degraded by heme oxygenases (HOs), and the iron product is reutilized by the body. To specify the processes of heme uptake and degradation, and the reutilization of iron, we determined the subcellular localizations of these transporters and HOs.</p> <p>Results</p> <p>In this study, we analyzed the subcellular localizations of 2 isoenzymes of HOs, 4 isoforms of divalent metal transporter 1 (DMT1), and 2 candidate heme transporters--heme carrier protein 1 (HCP1) and heme responsive gene-1 (HRG-1)--in non-polarized and polarized cells. In non-polarized cells, HCP1, HRG-1, and DMT1A-I are located in the plasma membrane. In polarized cells, they show distinct localizations: HCP1 and DMT1A-I are located in the apical membrane, whereas HRG-1 is located in the basolateral membrane and lysosome. 16Leu at DMT1A-I N-terminal cytosolic domain was found to be crucial for plasma membrane localization. HOs are located in smooth endoplasmic reticulum and colocalize with NADPH-cytochrome P450 reductase.</p> <p>Conclusions</p> <p>HCP1 and DMT1A-I are localized to the apical membrane, and HRG-1 to the basolateral membrane and lysosome. These findings suggest that HCP1 and DMT1A-I have functions in the uptake of dietary heme and non-heme iron. HRG-1 can transport endocytosed heme from the lysosome into the cytosol. These localization studies support a model in which cytosolic heme can be degraded by HOs, and the resulting iron is exported into tissue fluids via the iron transporter ferroportin 1, which is expressed in the basolateral membrane in enterocytes or in the plasma membrane in macrophages. The liberated iron is transported by transferrin and reutilized for hemoglobin synthesis in the erythroid system.</p

Paradoxical nature of narrative in analytical psychotherapy

This study explored the changes, obstacles for changes and the sharing of narratives in psychotherapeutic case studies. Study 1 developed an index for analyzing the process of narratives in psychotherapy, based on 101 cases. In Study 2, 203 cases were evaluated using the index generated from Study 1. As a result, three paradoxical natures of narrative became evident. Narrative in psychotherapy is thought to include (1) recognizing the beginning of a narrative, which can also signify the completion of the narrative, (2) negative movements that hinder the development of the narrative while at the same time move it forward and (3) an individual’s narrative that is uniquely one’s own, but easily influences and is influenced by the narratives of others

Cognitive flexibility in 12-month-old preterm and term infants is associated with neurobehavioural development in 18-month-olds

早産児の注意の切り替えの弱さは後の認知発達と関連する --アイトラッカーを用いた注意機能の定量的分析から--. 京都大学プレスリリース. 2022-01-11.There is growing evidence that preterm children are at an increased risk of poor executive functioning, which underlies behavioural and attention problems. Previous studies have suggested that early cognitive flexibility is a possible predictor of later executive function; however, how it develops in infancy and relates to the later neurobehavioural outcomes is still unclear in the preterm population. Here, we conducted a longitudinal study to investigate oculomotor response shifting in 27 preterm and 25 term infants at 12 months and its relationship with general cognitive development and effortful control, which is a temperamental aspect closely associated with executive function, at 18 months. We found that moderate to late preterm and term infants significantly inhibited previously rewarded look responses, while very preterm infants did not show significant inhibition of perseverative looking at 12 months. Moreover, lower inhibition of perseverative looking was significantly associated with lower general cognitive development and attentional shifting at 18 months. These findings suggest that the early atypical patterns of oculomotor response shifting may be a behavioural marker for predicting a higher risk of negative neurobehavioural outcomes, including attention-related problems in preterm children

Ultra-Shallow DoF Imaging Using Faced Paraboloidal Mirrors

Computer Vision - ACCV 2016: 13th Asian Conference on Computer Vision, Nov 20-24, 2016, Taipei, TaiwanWe propose a new imaging method that achieves an ultra-shallow depth of field (DoF) to clearly visualize a particular depth in a 3-D scene. The key optical device consists of a pair of faced paraboloidal mirrors with holes around their vertexes. In the device, a lens-less image sensor is set at one side of their holes and an object is set at the opposite side. The characteristic of the device is that the shape of the point spread function varies depending on both the positions of the target 3-D point and the image sensor. By leveraging this characteristic, we reconstruct a clear image for a particular depth by solving a linear system involving position-dependent point spread functions. In experiments, we demonstrate the effectiveness of the proposed method using both simulation and an actually developed prototype imaging system