285 research outputs found

    Luzes e farpas sob os camarotes: Rousseau, Rameau e a Querela dos Bufões

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    Frequentemente, os inflamados debates estético-musicais que estiveram em pauta na França da segunda metade do século XVIII e que deram origem ao episódio conhecido como Querela dos Bufões foram reduzidos a um curioso anedotário ou a uma guerra panfletária produzida tão somente pelos humores de seus aguerridos combatentes, os quais, postados sob os camarotes reais e divididos em defensores da tradição musical francesa e entusiastas da música italiana, disparavam críticas mútuas, sob a forma de panfletos, a exemplo das farpas lançadas por Jean-Jacques Rousseau, filósofo e músico autodidata, contra os partidários da música francesa e, especialmente, contra seu arqui-inimigo na cena musical da Ilustração, o renomado compositor e teórico da música Jean-Philippe Rameau. No presente artigo, para além da reconstituição histórica da famosa Guerra dos Bufões, procedemos à análise dos próprios argumentos apresentados por Rousseau em sua ardorosa, porém articulada defesa da ópera italiana em contraposição à ópera versalhesa, tais como aqueles expostos em sua Carta sobre a música francesa

    Apresentação a Sobre o gosto de J.-J. Rousseau

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    Sobre o gosto, de J.-J. Rousseau (Tradução de Fabio Stieltjes Yasoshima

    O Turismo e as normas ISO 9000: um caminho para a certificação da qualidade dos produtos e serviços

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    Um novo cenário econômico mundial mostra que a qualidade dos produtos e serviços é uma exigência crescente. O turismo, uma das atividades mais importantes da atualidade, deve levar as empresas do setor a adotar uma nova postura visando a qualidade e a produtividade. A certificação de um sistema de qualidade total é o melhor caminho para o reconhecimento internacional.A new world economic scenery shows the increasement of products and services quality request. While one of the most important activity tourism requires a new position of all turistic organizations in the way of quality and productivity. The total quality system certification is the best way for a world-wide recognition

    Revealing the hidden dynamics of confined water in acrylate polymers: Insights from hydrogen-bond lifetime analysis

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    Polymers contain functional groups that participate in hydrogen bond (H-bond) with water molecules, establishing a robust H-bond network that influences bulk properties. This study utilized molecular dynamics (MD) simulations to examine the H-bonding dynamics of water molecules confined within three poly(meth)acrylates: poly(2-methoxyethyl acrylate) (PMEA), poly(2-hydroxyethyl methacrylate) (PHEMA), and poly(1-methoxymethyl acrylate) (PMC1A). Results showed that H-bonding dynamics significantly slowed as the water content decreased. Additionally, the diffusion of water molecules and its correlation with H-bond breakage were analyzed. Our findings suggest that when the H-bonds between water molecules and the methoxy oxygen of PMEA are disrupted, those water molecules persist in close proximity and do not diffuse on a picosecond timescale. In contrast, the water molecules H-bonded with the hydroxy oxygen of PHEMA and the methoxy oxygen of PMC1A diffuse concomitantly with the breakage of H-bonds. These results provide an in-depth understanding of the impact of polymer functional groups on H-bonding dynamics.Comment: 11 pages, 8 figures for main text, 10 pages for supplementary material, to appear in J. Chem. Phy

    Diffusion-Controlled Recrystallization of Water Sorbed into Poly(meth)acrylates Revealed by Variable-Temperature Mid-Infrared Spectroscopy and Molecular Dynamics Simulation.

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    Recrystallization behaviors of water sorbed into four poly(meth)acrylates, poly(2-methoxyethyl acrylate), poly(tetrahydrofurfuryl acrylate), poly(methyl acrylate), and poly(methyl methacrylate), are investigated by variable-temperature mid-infrared (VT-MIR) spectroscopy and molecular dynamics (MD) simulation. VT-MIR spectra demonstrate that recrystallization temperatures of water sorbed into the polymers are positively correlated with their glass-transition temperatures reported previously. The present MD simulation shows that a lower-limit temperature of the diffusion for the sorbed water and the glass-transition temperatures of the polymers also have a positive correlation, indicating that the recrystallization is controlled by diffusion mechanism rather than reorientation mechanism. Detailed molecular processes of not only recrystallization during rewarming but also crystallization during cooling and hydrogen-bonding states of water in the polymers are systematically analyzed and discussed

    Da imitação teatral, ou “Ensaio extraído dos Diálogos de Platão”

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    Tradução de Da imitação teatral, ou “Ensaio extraído dos Diálogos de Platão”, de J-J Roussea

    Gastric T-cell lymphoma associated with hemophagocytic syndrome

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    BACKGROUND: Lymphoma-associated hemophagocytic syndrome (LAHS) occurs in mostly extra nodal non-Hodgkin's lymphoma. LAHS arising from gastrointestinal lymphoma has never been reported. Here we report a case of gastric T-cell lymphoma-associated hemophagocytic syndrome. CASE PRESENTATION: A 51-year-old woman presented with pain, redness of breasts, fever and hematemesis. Hematological examination revealed anemia. Gastroscopy revealed small bleeding ulcers in the stomach and the computed tomography scan showed liver tumor. She underwent total gastrectomy for gastrointestinal bleeding and the histopathology revealed gastric T-cell lymphoma. She continued to bleed from the anastomosis and died on the 8th postoperative day. Autopsy revealed it to be a LAHS. CONCLUSIONS: If Hemophagocytic syndrome (HPS) occurs in lymphoma of the gastrointestinal tract, bleeding from the primary lesion might be uncontrollable. Early diagnosis and appropriate treatment are needed for long-term survival

    The relationship between the expressions of the cell adhesion molecule CD44H, CD44v3, and CD44v6 and metastases in gastric cancer

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    Expression of CD44 variants in some tissues appears to relate to tumor progression, and particularly to the metastatic potential of some cancers. The aim of this study was to clarify the relation between the expression of CD44 splice variants and tumor metastasis by using CD44v-specific gastric cancer monoclonal antibodies. A total of 110 patients with primary gastric cancer were studied. Histological samples of 70 of the 110 (63.6%) were stained with three monoclonal antibodies directed against the CD44H and CD44 variants (CD44v3, CD44v6) in gastric cancer. The incidence of lymph node metastasis was higher in the CD44H strongerexpression group than in the weaker expression group. No significant correlation could be found between CD44H, CD44V3, or CD44v6 expression and liver metastasis or histological types (differentiated vs.undifferentiated) . Lymph node metastasis correlated with CH44H rather than CD44v3 or CD44v6. These results suggested that CD44H might be a useful marker for lymph node metastasis in resected gas-tric cancer. The 5-year survival rate was 57.3% in the group positively ex-pressing CD44 and 52.4% in the group with negative expression of CD44. Concerning prognosis, we found here that the expression of CD44 is not sig-nificantly associated with increased mortality. Further study of the expression of specific isoforms may help elucidate in more detail the mechanisms of these findings
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