Selectivity and activity in catalytic hydrogenation of azido groups over Pd nanoparticles on aluminum oxy-hydroxide

WOS: 000387621500067Azidoarenes involving various functional groups were successfully reduced to aniline derivatives using commercially available aluminium oxy-hydroxide-supported palladium (Pd/AlO(OH)) nanoparticles ( 0.5 wt% Pd) in an aqueous medium with sodium borohydride as the hydrogen source. To develop the green process, water was utilized in conjunction with methanol. The results demonstrated that the halogen substituted azidoarenes were selectively converted to the corresponding aniline compounds without dehalogenation. In general, all of the reactions were completed within 10-30 min at room temperature with yields of over 99%. In order to optimize the reaction conditions, the parametric effects of the solvent type and the amount of the catalyst/NaBH4 were examined. Consequently, for the first time, a novel, practical and environmentally friendly process was developed for the conversion of azidoarenes to aniline derivatives in the fluence of Pd/AlO(OH) nanoparticles.Duzce UniversityDuzce University [2014.05.03.243, 2015.26.04.371]This research was supported by Duzce University Research Fund (grant no. 2014.05.03.243 and 2015.26.04.371)

A practical and highly efficient reductive dehalogenation of aryl halides using heterogeneous Pd/AlO(OH) nanoparticles and sodium borohydride

WOS: 000383300700009The reductive dehalogenation of aryl halides was performed by using commercially available aluminium oxy-hydroxide-supported palladium (Pd/AlO(OH)) nanoparticles of about 3 nm size (0.5 wt. % Pd) with sodium borohydride. The dehalogenated products were obtained with absolute conversion in a mixture of H2O/MeOH (v/v=1/1) under ultrasonic conditions at room temperature. All aryl halides were successfully converted to halogen-free compounds within 1.5-4 h with yields of over 95%. The one-pot catalytic method is presented as a new process for the reductive dehalogenation of halogenated compounds. This method is quite simple, highly efficient and eco-friendly, and has an exceptional recovery rate. (C) 2016 Elsevier Ltd. All rights reserved.Duzce University Research FundDuzce University [2014.05.03.243, 2015.26.04.371]This research was supported by Duzce University Research Fund (grant nos. 2014.05.03.243 and 2015.26.04.371)

Adile Sultan Sarayı'ndan Kandilli Kız Lisesi'ne yolculuk

Ankara : İhsan Doğramacı Bilkent Üniversitesi İktisadi, İdari ve Sosyal Bilimler Fakültesi, Tarih Bölümü, 2018.This work is a student project of the Department of History, Faculty of Economics, Administrative and Social Sciences, İhsan Doğramacı Bilkent University.The History of Turkey course (HIST200) is a requirement for all Bilkent undergraduates. It is designed to encourage students to work in groups on projects concerning any topic of their choice that relates to the history of Turkey. It is designed as an interactive course with an emphasis on research and the objective of investigating events, chronologically short historical periods, as well as historic representations. Students from all departments prepare and present final projects for examination by a committee, with 10 projects chosen to receive awards.Includes bibliographical references (page 13).by İbrahim Mert Öztürk

Türkiye'de Ayaş domatesi'nin ortaya çıkışı ve gelişimi

Ankara : İhsan Doğramacı Bilkent Üniversitesi İktisadi, İdari ve Sosyal Bilimler Fakültesi, Tarih Bölümü, 2018.This work is a student project of the Department of History, Faculty of Economics, Administrative and Social Sciences, İhsan Doğramacı Bilkent University.The History of Turkey course (HIST200) is a requirement for all Bilkent undergraduates. It is designed to encourage students to work in groups on projects concerning any topic of their choice that relates to the history of Turkey. It is designed as an interactive course with an emphasis on research and the objective of investigating events, chronologically short historical periods, as well as historic representations. Students from all departments prepare and present final projects for examination by a committee, with 10 projects chosen to receive awards.Includes bibliographical references (page 14).by Abdürrahim Özer

Clinical Characteristics of Seizures in Epilepsy after Stroke: Prognosis and Treatment

Objectives:The aim of the present study was to determine demographic properties and risk factors for early- and late-onset seizures, as well as the effects of these factors on prognosis of patients with post-stroke epilepsy.Methods:Only patients with post-stroke epilepsy were included in this retrospective study. Demographic properties, stroke type, time interval between stroke and onset of seizure, neuroimaging, EEG characteristics, antiepileptic therapy, and prognosis were assessed.Results:Forty-five patients were included; 23 (51%) were female, and 22 (49%) were male. Mean age of study population was 64.6±1.3 (23–84). Sixty percent (n=27) of patients had early-onset seizures, and 40% (n=18) had late-onset seizures. Thirty-four patients had an ischemic stroke, and 11 had a hemorrhagic stroke. Most prevalent etiologic factor in the ischemic strokes was a cardioembolic stroke (15%). Middle-cerebral-artery infarcts were the most frequently observed arterial stroke region. In hemorrhagic stroke lobar, hemorrhages (54%) were more prevalent, and 87% of patients received monotherapy. Levetiracetam was the most commonly preferred medication, followed by carbamazepine, valproic acid, and oxcarbazepine, in descending order. Of the early-onset seizures, 63% were controlled with medication, as were 55% of the late-onset seizures. A statistically significant difference was observed between post-stroke localization and timing of seizure.Conclusion:Post-stroke seizures may present as early- or late-onset due to various underlying pathophysiologic mechanisms and prognostic properties. These seizures are affected by a variety of factors and are frequently controlled with monotherapy

Swiss (German) version of the Actinic Keratosis Quality of Life questionnaire

Actinic keratosis (AK) is a sun-induced skin lesion that may progress to invasive squamous cell carcinoma of the skin. Recently, the Actinic Keratosis Quality of Life questionnaire (AKQoL) was designed for patients with AK in Denmark as a specific quality of life instrument for AK patients