Network-State Modulation of Power-Law Frequency-Scaling in Visual Cortical Neurons

Various types of neural-based signals, such as EEG, local field potentials and intracellular synaptic potentials, integrate multiple sources of activity distributed across large assemblies. They have in common a power-law frequency-scaling structure at high frequencies, but it is still unclear whether this scaling property is dominated by intrinsic neuronal properties or by network activity. The latter case is particularly interesting because if frequency-scaling reflects the network state it could be used to characterize the functional impact of the connectivity. In intracellularly recorded neurons of cat primary visual cortex in vivo, the power spectral density of Vm activity displays a power-law structure at high frequencies with a fractional scaling exponent. We show that this exponent is not constant, but depends on the visual statistics used to drive the network. To investigate the determinants of this frequency-scaling, we considered a generic recurrent model of cortex receiving a retinotopically organized external input. Similarly to the in vivo case, our in computo simulations show that the scaling exponent reflects the correlation level imposed in the input. This systematic dependence was also replicated at the single cell level, by controlling independently, in a parametric way, the strength and the temporal decay of the pairwise correlation between presynaptic inputs. This last model was implemented in vitro by imposing the correlation control in artificial presynaptic spike trains through dynamic-clamp techniques. These in vitro manipulations induced a modulation of the scaling exponent, similar to that observed in vivo and predicted in computo. We conclude that the frequency-scaling exponent of the Vm reflects stimulus-driven correlations in the cortical network activity. Therefore, we propose that the scaling exponent could be used to read-out the “effective” connectivity responsible for the dynamical signature of the population signals measured at different integration levels, from Vm to LFP, EEG and fMRI

Geomorphic Terrains and Evidence for Ancient Volcanism within Northeastern South Pole-Aitken Basin

The interior of the enigmatic South Pole-Aitken Basin has long been recognized as being compositionally distinct from its exterior. However, the source of the compositional anomaly has been subject to some debate. Is the source of the iron-enhancement due to lower-crustal/upper-mantle material being exposed at the surface, or was there some volume of ancient volcanism that covered portions of the basin interior? While several obvious mare basalt units are found within the basin and regions that appear to represent the original basin interior, there are several regions that appear to have an uncertain origin. Using a combination of Clementine and Lunar Orbiter images, several morphologic units are defined based on albedo, crater density, and surface roughness. An extensive unit of ancient mare basalt (cryptomare) is defined and, based on the number of superimposed craters, potentially represents the oldest volcanic materials within the basin. Thus, the overall iron-rich interior of the basin is not solely due to deeply derived crustal material, but is, in part due to the presence of ancient volcanic units

The Survey of HI in Extremely Low-mass Dwarfs: A Multi-Wavelength Perspective on Low-Mass Galaxy Evolution

The “Survey of HI in Extremely Low-mass Dwarfs” (SHIELD) is a multiwavelength study of local volume low-mass galaxies drawn from the Arecibo Legacy Fast ALFA (ALFALFA) catalog. HST/Spitzer joint program GO-12658 revealed the stellar populations of the first 12 SHIELD galaxies (Cannon et al. 2011), allowing accurate distance measurements (McQuinn et al. 2014) and detailed studies of the patterns of recent star formation in each galaxy (McQuinn et al. 2015). These HST and Spitzer images are a critical interpretive benchmark for ground-based optical imaging and spectroscopy (Haurberg et al. 2015), as well as for sensitive VLA HI spectral line imaging of the SHIELD galaxies (McNichols et al. 2016; Teich et al. 2016). These results have furthered our understanding of the evolution of galaxies in a mass regime that was previously only sparsely populated. With the low-redshift ALFALFA catalog now complete, the scope of the SHIELD program has been expanded to include all 82 galaxies that meet distance, line width, and HI flux criteria for being gas-rich, low-mass galaxies. In HST program 13750, images of 18 more SHIELD galaxies have again set the physical scales for supporting HI spectral line imaging with both the VLA and the WSRT (Gordon et al. 2016). Taken as a whole, the ongoing SHIELD program is one of the most comprehensive multiwavelength studies of the physical properties of low-mass galaxies outside of the Local Group

SHIELD: EVLA HI Spectral Line Observations of Low-mass Dwarfs

The “Survey of HI in Extremely Low-mass Dwarfs” (SHIELD) is a multiwavelength study of local volume low-mass galaxies. Using the now-complete Arecibo Legacy Fast ALFA (ALFALFA) source catalog, 82 systems are identified that meet distance, line width, and HI flux criteria for being gas-rich, low-mass galaxies. These systems harbor neutral gas reservoirs smaller than 3x10^7 M_sun, thus populating the faint end of the HI mass function with statistical confidence for the first time. Here we present new Karl G. Jansky Very Large Array D-configuration HI spectral line observations of 32 previously unobserved galaxies. These low angular resolution (~40" beam) images localize the HI gas; with a few exceptions, the HI gas is co-spatial with the optical centers of the galaxies. These images provide the first glimpse of the neutral interstellar medium in these systems.Support for this work was provided by NSF grant 1211683 to JMC at Macalester College