13 research outputs found
A quantitative study on the thermomechanical coupling effect of elasticity and plasticity of polymethyl methacrylate
Quantitative study on the elastic and plastic thermomechanical coupling effect of solid materials has important theoretical significance for monitoring the deformation state and stability evaluation of engineering components. In this study, the sample is made of polymethyl methacrylate (PMMA), and uniaxial compression experiments are carried out. The sample experiences the elastic state and then the plastic state until the failure of the sample. The thermoelastic effect and thermoplastic effect in the deformation process of PMMA materials are monitored by infrared thermography and digital speckle system (DIC). That is, the relationship between the reversible elastic temperature change ĪTe and average stress change ĪĻm, and the relationship between the irreversible plastic temperature rise ĪTp and the dissipated energy ĪUp during the failure deformation process. The results show that when the sample is in the elastic regime, there is only elastic temperature change ĪTe inside the sample. When the sample enters the plastic deformation regime, the total temperature change ĪT includes elastic temperature change ĪTe and plastic temperature change ĪTp, and the temperature change has an obvious memory effect on the previous maximum load. When the previous maximum load exceeded, ĪTp increases rapidly. When the load P is removed, ĪTe disappears, and ĪTp remains. Combined with the theory of thermodynamics and solid mechanics, starting from the 3D stress state, the approximate linear incremental relationship between Te and Ļm, and the accurate exponential total quantity relationship are derived. The incremental relationship and the full relationship combined with thermodynamic theory and the energy conservation principle, the relationship between the overall plastic temperature rise ĪTp and local plastic temperature rise ĪTpmax of the sample and the energy dissipation value ĪUp experienced by the sample and the local dissipation specific energy Īup is obtained. The theoretical calculation results of ĪTe and ĪTp are in good agreement with the experimental results. The research results can provide a new method for monitoring and identifying the stress and deformation state of engineering components through the temperature field
Ultrasonic surface rolling strengthening and its parameter optimization on bearing raceway
For the first time, the ultrasonic surface rolling processing (USRP) technology was applied to a real bearing raceway, and a finite element simulation model for USRP on a bearing raceway was established. Practical tests were conducted to evaluate the surface integrity of the bearing raceway before and after USRP treatment. The USRP parameters were optimized using Taguchi-gray correlation analysis. The results show that the optimal process parameters for the 7224 bearing raceway are: an amplitude of 10Ā Ī¼m, a static pressure of 2400Ā N, a spindle speed of 45Ā rad/min, and rolling times of 7. In the process of USRP, residual compressive stress results from inhomogeneous elastic and plastic deformation. Adjacent tempered martensitic laths merge and deflect at a certain angle along the rolling direction to form directional grain stacks, resulting in a flocculent plastic deformation layer. The USRP based on the finishing mechanism of āpeak-cutting and valley-fillingā can improve the surface micro-morphology, reduce roughness value Ra to approximately 0.16Ā Ī¼m, and effectively eliminate microscopic cracks caused by grinding. The micro-hardness of the bearing raceway surface increased from 760 HV to 840 HV under the dual action of surface grain refinement and work hardening effect
Consistent signatures in the human gut microbiome of old- and young-onset colorectal cancer
Abstract The incidence of young-onset colorectal cancer (yCRC) has been increasing in recent decades, but little is known about the gut microbiome of these patients. Most studies have focused on old-onset CRC (oCRC), and it remains unclear whether CRC signatures derived from old patients are valid in young patients. To address this, we assembled the largest yCRC gut metagenomes to date from two independent cohorts and found that the CRC microbiome had limited association with age across adulthood. Differential analysis revealed that well-known CRC-associated taxa, such as Clostridium symbiosum, Peptostreptococcus stomatis, Parvimonas micra and Hungatella hathewayi were significantly enriched (false discovery rate <0.05) in both old- and young-onset patients. Similar strain-level patterns of Fusobacterium nucleatum, Bacteroides fragilis and Escherichia coli were observed for oCRC and yCRC. Almost all oCRC-associated metagenomic pathways had directionally concordant changes in young patients. Importantly, CRC-associated virulence factors (fadA, bft) were enriched in both oCRC and yCRC compared to their respective controls. Moreover, the microbiome-based classification model had similar predication accuracy for CRC status in old- and young-onset patients, underscoring the consistency of microbial signatures across different age groups